JPH02289557A - 新規な５―アシルベンゾキサゾリノン誘導体 - Google Patents

新規な５―アシルベンゾキサゾリノン誘導体

Info

Publication number
JPH02289557A
JPH02289557A JP2080574A JP8057490A JPH02289557A JP H02289557 A JPH02289557 A JP H02289557A JP 2080574 A JP2080574 A JP 2080574A JP 8057490 A JP8057490 A JP 8057490A JP H02289557 A JPH02289557 A JP H02289557A
Authority
JP
Japan
Prior art keywords
formula
group
lower alkyl
derivative
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2080574A
Other languages
English (en)
Japanese (ja)
Inventor
Daniel Lesieur
ダニエル　ルシュール
Hocine Aichaoui
オシン　エシャウイ
Charles Lespagnol
シャルル　ルスパニョル
Jacqueline Bonnet
ジャックリン　ボンネ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Servier de Medecine Translationnelle SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of JPH02289557A publication Critical patent/JPH02289557A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2080574A 1989-03-30 1990-03-28 新規な５―アシルベンゾキサゾリノン誘導体 Pending JPH02289557A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8904129 1989-03-30
FR8904129A FR2645149A1 (enExample) 1989-03-30 1989-03-30

Publications (1)

Publication Number Publication Date
JPH02289557A true JPH02289557A (ja) 1990-11-29

Family

ID=9380179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2080574A Pending JPH02289557A (ja) 1989-03-30 1990-03-28 新規な５―アシルベンゾキサゾリノン誘導体

Country Status (9)

Country Link
EP (1) EP0390673A1 (enExample)
JP (1) JPH02289557A (enExample)
AU (1) AU621726B2 (enExample)
CA (1) CA2013322A1 (enExample)
FR (1) FR2645149A1 (enExample)
NZ (1) NZ233129A (enExample)
OA (1) OA09444A (enExample)
PT (1) PT93605A (enExample)
ZA (1) ZA902316B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182278A (en) * 1989-02-28 1993-01-26 Adir Et Compagnie Analgesic benzoxazolinones having at the 6-position a 1-hydroxy-3-morpholinopropyl side chain
FR2663634B1 (fr) * 1990-06-22 1992-09-04 Adir Nouvelles acyl benzoxazolinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2756825B1 (fr) * 1996-12-10 1999-01-08 Adir Nouveaux derives [3h]-benzoxazole-2-thiones et [3h]- benzothiazole-2-thiones substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5069073A (enExample) * 1973-06-26 1975-06-09
JPS57501427A (enExample) * 1980-09-29 1982-08-12
JPS59186983A (ja) * 1983-02-25 1984-10-23 Fujisawa Pharmaceut Co Ltd イミダゾ複素環化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3161649A (en) * 1962-03-05 1964-12-15 White Lab Substituted benzoxazoles
FR2244507A1 (en) * 1973-06-26 1975-04-18 Inst Nat Sante Rech Med Chalcones and analogues - analgesics having low toxicity
FR2409991B2 (fr) * 1977-11-29 1980-05-16 Inst Nat Sante Rech Med (chloro-2' benzoyl)-6 benzoxazolinone, utilisable comme medicament

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5069073A (enExample) * 1973-06-26 1975-06-09
JPS57501427A (enExample) * 1980-09-29 1982-08-12
JPS59186983A (ja) * 1983-02-25 1984-10-23 Fujisawa Pharmaceut Co Ltd イミダゾ複素環化合物

Also Published As

Publication number Publication date
ZA902316B (en) 1990-12-28
CA2013322A1 (fr) 1990-09-30
OA09444A (fr) 1992-10-15
PT93605A (pt) 1990-11-20
EP0390673A1 (fr) 1990-10-03
AU621726B2 (en) 1992-03-19
AU5235690A (en) 1990-10-04
NZ233129A (en) 1992-03-26
FR2645149A1 (enExample) 1990-10-05

Similar Documents

Publication Publication Date Title
JP3148253B2 (ja) ベンゾフリル誘導体類及びそれらの用途
JPWO2000050395A1 (ja) スルホンアミド含有インドール化合物
JPH026473A (ja) 置換フラボノイド化合物、それらの塩、製法およびこれらを含有する医薬
JPH11506109A (ja) Ｃｎｓ活性を有するセミカルバゾンおよびそれを含む医薬製剤
JPS63502031A (ja) ヒドロキシおよびアミノチオゾリル−ベンゾジアジノン化合物、これを含む強心性組成物、およびその使用
JP7025555B2 (ja) 一過性受容体電位ａ１イオンチャネルの阻害
JPH0662562B2 (ja) ピロール酢酸アミド
JPS62111962A (ja) ３−フエニルチオメチルスチレン誘導体
JPS6028979A (ja) イミダゾキナゾリン類化合物
JPH0222059B2 (enExample)
JPS59205339A (ja) ロイコトリエン「きっ」抗物質
JPS5841862A (ja) 複素環式酢酸化合物および骨疾患の治療用組成物
JPH0433793B2 (enExample)
JPH01228975A (ja) ベンゾチアジン―１，１―ジオキシド誘導体及びそれを含有する医薬組成物
CN104840461B (zh) 一类反式‑1‑(吲哚‑3‑基)‑2‑(喹啉‑4‑基)‑乙烯衍生物的用途及组合物
JPH0356473A (ja) シクロオキシゲナーゼと５―リポキシゲナーゼの二重阻害剤である新規な７―アローイル―４―ヒドロキシ―３―メチル―ベンゾフラン
JPH0352875A (ja) ４，５，６，７，―四置換ベンゾオキサゾロン類
JPS63185926A (ja) 肝臓疾患治療剤
JP2678768B2 (ja) テトラヒドロイミダゾ［２，１−ｂ］ベンゾチアゾール誘導体及び該化合物を有効成分とする抗潰瘍剤
JPH02295984A (ja) 新規なベンゾチアゾリノン誘導体
CN112778201B (zh) 一种苯并[b]氮杂䓬-查尔酮杂合物及其制备方法和用途
US7345079B2 (en) Treatment of disorder related to low cyclic GMP levels
JPH02250831A (ja) ３，４―ジヒドロ―２ｈ―ベンゾピラン誘導体及びそれを有効成分とする抗消化性潰瘍剤
JPS59225187A (ja) テトラヒドロ−β−カルボリン誘導体及びその製法
JP3092827B2 (ja) アルケンアミド誘導体及びそのアルケンアミド誘導体を用いた抗アレルギー剤、アルケン酸、そのアルケン酸の製造方法