JPH0226634B2 - - Google Patents
Info
- Publication number
- JPH0226634B2 JPH0226634B2 JP56024828A JP2482881A JPH0226634B2 JP H0226634 B2 JPH0226634 B2 JP H0226634B2 JP 56024828 A JP56024828 A JP 56024828A JP 2482881 A JP2482881 A JP 2482881A JP H0226634 B2 JPH0226634 B2 JP H0226634B2
- Authority
- JP
- Japan
- Prior art keywords
- formula
- iodide
- ester
- iodomethyl
- carboxylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/122,950 US4266049A (en) | 1980-02-20 | 1980-02-20 | Process for 3-iodomethyl cephalosporins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56131590A JPS56131590A (en) | 1981-10-15 |
| JPH0226634B2 true JPH0226634B2 (cg-RX-API-DMAC7.html) | 1990-06-12 |
Family
ID=22405854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2482881A Granted JPS56131590A (en) | 1980-02-20 | 1981-02-20 | Manufacture of 3-iodomethylcephalosporins |
Country Status (28)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409214A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical, Co., Ltd. | 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
| NL8005041A (nl) * | 1980-09-05 | 1982-04-01 | Gist Brocades Nv | Werkwijze voor de bereiding van thioethers, alsmede gesilyleerde thiolen voor toepassing bij deze werkwijze. |
| FR2494276A2 (fr) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | Nouvelles vinyl-3 cephalosporines, et leur preparation |
| AT389515B (de) * | 1982-03-29 | 1989-12-27 | Bristol Myers Co | Verfahren zur herstellung von neuen cephalosporinverbindungen |
| DE3316798A1 (de) * | 1983-05-07 | 1984-11-08 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von cephemverbindungen |
| DE3316797A1 (de) * | 1983-05-07 | 1984-11-08 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von cephemverbindungen |
| AU566944B2 (en) * | 1983-10-07 | 1987-11-05 | Gist-Brocades N.V. | Preparation of 3-cephem derivatives |
| DE3588014D1 (de) * | 1984-11-23 | 1995-06-01 | Biochemie Gmbh | Verfahren zur herstellung bissilylierter 3-iodmethylcephalosporinderivaten. |
| AT381315B (de) * | 1984-11-23 | 1986-09-25 | Biochemie Gmbh | Verfahren zur herstellung von cephalosporinderivaten |
| US4703118A (en) * | 1985-04-08 | 1987-10-27 | Eli Lilly And Company | Synthesis of 3-iodomethyl cephalosporins |
| US4749522A (en) * | 1985-10-31 | 1988-06-07 | Angio-Medical Corporation | Supercritical fluid extraction of animal derived materials |
| ZA874696B (en) | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
| KR940000112B1 (ko) * | 1990-07-05 | 1994-01-05 | 주식회사 대웅제약 | 신규의 3-치환 세펨화합물 및 그의 제조방법 |
| KR100194994B1 (ko) * | 1993-06-05 | 1999-06-15 | 손경식 | 새로운 세펨 화합물 |
| KR100390548B1 (ko) * | 1996-02-10 | 2003-11-13 | 주식회사 코오롱 | 세팔로스포린 중간체의 제조방법 |
| FR2770218B1 (fr) * | 1997-10-27 | 2000-02-18 | Rhodia Chimie Sa | Procede de silylation d'hydrates de carbone |
| DE602004028111D1 (de) | 2003-04-16 | 2010-08-26 | Sandoz Ag | Verfahren zur herstellung von cefepim |
| US7847093B2 (en) * | 2003-04-16 | 2010-12-07 | Sandoz Ag | Processes for the preparations of cefepime |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1241657A (en) * | 1967-08-21 | 1971-08-04 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin compounds |
| US4042585A (en) * | 1976-03-22 | 1977-08-16 | Eli Lilly And Company | Process for preparation of 3-halomethylcephems |
-
1980
- 1980-02-20 US US06/122,950 patent/US4266049A/en not_active Expired - Lifetime
-
1981
- 1981-02-10 NZ NZ196228A patent/NZ196228A/xx unknown
- 1981-02-10 CA CA000370551A patent/CA1147322A/en not_active Expired
- 1981-02-10 GR GR64092A patent/GR72415B/el unknown
- 1981-02-12 PH PH25216A patent/PH15823A/en unknown
- 1981-02-12 IL IL62118A patent/IL62118A/xx not_active IP Right Cessation
- 1981-02-13 YU YU00375/81A patent/YU37581A/xx unknown
- 1981-02-16 AU AU67335/81A patent/AU538543B2/en not_active Ceased
- 1981-02-17 RO RO103444A patent/RO81620B/ro unknown
- 1981-02-18 PT PT72532A patent/PT72532B/pt not_active IP Right Cessation
- 1981-02-19 DE DE8181300695T patent/DE3164498D1/de not_active Expired
- 1981-02-19 HU HU81404A patent/HU183340B/hu not_active IP Right Cessation
- 1981-02-19 SU SU813247948A patent/SU1069627A3/ru active
- 1981-02-19 FI FI810505A patent/FI810505A7/fi not_active Application Discontinuation
- 1981-02-19 EP EP81300695A patent/EP0034924B1/en not_active Expired
- 1981-02-19 KR KR1019810000521A patent/KR840000503B1/ko not_active Expired
- 1981-02-19 CS CS811206A patent/CS225827B2/cs unknown
- 1981-02-19 DK DK73381A patent/DK73381A/da not_active Application Discontinuation
- 1981-02-19 AT AT81300695T patent/ATE8261T1/de not_active IP Right Cessation
- 1981-02-19 ES ES499609A patent/ES8202560A1/es not_active Expired
- 1981-02-19 GB GB8105307A patent/GB2070598B/en not_active Expired
- 1981-02-19 IE IE336/81A patent/IE50929B1/en not_active IP Right Cessation
- 1981-02-19 AR AR284363A patent/AR226202A1/es active
- 1981-02-20 JP JP2482881A patent/JPS56131590A/ja active Granted
- 1981-02-20 BG BG050916A patent/BG35330A3/xx unknown
- 1981-02-20 PL PL1981229788A patent/PL127858B1/pl unknown
- 1981-02-20 ZA ZA00811158A patent/ZA811158B/xx unknown
- 1981-02-20 DD DD81227789A patent/DD156533A5/de unknown
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