ATE8261T1 - Verfahren zur herstellung von 3-jodmethylcephalosporinen. - Google Patents

Verfahren zur herstellung von 3-jodmethylcephalosporinen.

Info

Publication number
ATE8261T1
ATE8261T1 AT81300695T AT81300695T ATE8261T1 AT E8261 T1 ATE8261 T1 AT E8261T1 AT 81300695 T AT81300695 T AT 81300695T AT 81300695 T AT81300695 T AT 81300695T AT E8261 T1 ATE8261 T1 AT E8261T1
Authority
AT
Austria
Prior art keywords
iodomethylcephalosporins
preparation
Prior art date
Application number
AT81300695T
Other languages
English (en)
Inventor
Rosanne Bonjouklian
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Application granted granted Critical
Publication of ATE8261T1 publication Critical patent/ATE8261T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT81300695T 1980-02-20 1981-02-19 Verfahren zur herstellung von 3-jodmethylcephalosporinen. ATE8261T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/122,950 US4266049A (en) 1980-02-20 1980-02-20 Process for 3-iodomethyl cephalosporins
EP81300695A EP0034924B1 (de) 1980-02-20 1981-02-19 Verfahren zur Herstellung von 3-Jodmethyl-cephalosporinen

Publications (1)

Publication Number Publication Date
ATE8261T1 true ATE8261T1 (de) 1984-07-15

Family

ID=22405854

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81300695T ATE8261T1 (de) 1980-02-20 1981-02-19 Verfahren zur herstellung von 3-jodmethylcephalosporinen.

Country Status (28)

Country Link
US (1) US4266049A (de)
EP (1) EP0034924B1 (de)
JP (1) JPS56131590A (de)
KR (1) KR840000503B1 (de)
AR (1) AR226202A1 (de)
AT (1) ATE8261T1 (de)
AU (1) AU538543B2 (de)
BG (1) BG35330A3 (de)
CA (1) CA1147322A (de)
CS (1) CS225827B2 (de)
DD (1) DD156533A5 (de)
DE (1) DE3164498D1 (de)
DK (1) DK73381A (de)
ES (1) ES8202560A1 (de)
FI (1) FI810505L (de)
GB (1) GB2070598B (de)
GR (1) GR72415B (de)
HU (1) HU183340B (de)
IE (1) IE50929B1 (de)
IL (1) IL62118A (de)
NZ (1) NZ196228A (de)
PH (1) PH15823A (de)
PL (1) PL127858B1 (de)
PT (1) PT72532B (de)
RO (1) RO81620B (de)
SU (1) SU1069627A3 (de)
YU (1) YU37581A (de)
ZA (1) ZA811158B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
NL8005041A (nl) * 1980-09-05 1982-04-01 Gist Brocades Nv Werkwijze voor de bereiding van thioethers, alsmede gesilyleerde thiolen voor toepassing bij deze werkwijze.
FR2494276A2 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles vinyl-3 cephalosporines, et leur preparation
AT389515B (de) * 1982-03-29 1989-12-27 Bristol Myers Co Verfahren zur herstellung von neuen cephalosporinverbindungen
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
AU566944B2 (en) * 1983-10-07 1987-11-05 Gist-Brocades N.V. Preparation of 3-cephem derivatives
AT381315B (de) * 1984-11-23 1986-09-25 Biochemie Gmbh Verfahren zur herstellung von cephalosporinderivaten
EP0612750B1 (de) * 1984-11-23 1999-03-03 BIOCHEMIE Gesellschaft m.b.H. Cephalosporinderivative
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
ZA874696B (en) 1986-07-03 1988-01-04 F. Hoffmann-La Roche & Co. Aktiengesellschaft Acyl derivatives
KR940000112B1 (ko) * 1990-07-05 1994-01-05 주식회사 대웅제약 신규의 3-치환 세펨화합물 및 그의 제조방법
KR100194994B1 (ko) * 1993-06-05 1999-06-15 손경식 새로운 세펨 화합물
KR100390548B1 (ko) * 1996-02-10 2003-11-13 주식회사 코오롱 세팔로스포린 중간체의 제조방법
FR2770218B1 (fr) * 1997-10-27 2000-02-18 Rhodia Chimie Sa Procede de silylation d'hydrates de carbone
US7847093B2 (en) * 2003-04-16 2010-12-07 Sandoz Ag Processes for the preparations of cefepime
ATE473986T1 (de) 2003-04-16 2010-07-15 Sandoz Ag Verfahren zur herstellung von cefepim

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241657A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
US4042585A (en) * 1976-03-22 1977-08-16 Eli Lilly And Company Process for preparation of 3-halomethylcephems

Also Published As

Publication number Publication date
PL229788A1 (de) 1981-11-13
EP0034924A2 (de) 1981-09-02
AU6733581A (en) 1981-08-27
DD156533A5 (de) 1982-09-01
NZ196228A (en) 1983-07-29
DK73381A (da) 1981-10-02
GR72415B (de) 1983-11-03
PH15823A (en) 1983-04-08
KR840000503B1 (ko) 1984-04-16
PT72532A (en) 1981-03-01
IE50929B1 (en) 1986-08-20
ES499609A0 (es) 1982-02-01
GB2070598B (en) 1984-02-22
ES8202560A1 (es) 1982-02-01
RO81620A (ro) 1983-04-29
SU1069627A3 (ru) 1984-01-23
KR830005242A (ko) 1983-08-03
HU183340B (en) 1984-04-28
JPH0226634B2 (de) 1990-06-12
CS225827B2 (en) 1984-02-13
IE810336L (en) 1981-08-20
YU37581A (en) 1983-09-30
ZA811158B (en) 1982-10-27
AU538543B2 (en) 1984-08-16
AR226202A1 (es) 1982-06-15
JPS56131590A (en) 1981-10-15
US4266049A (en) 1981-05-05
EP0034924B1 (de) 1984-07-04
PL127858B1 (en) 1983-11-30
PT72532B (en) 1982-02-10
GB2070598A (en) 1981-09-09
RO81620B (ro) 1983-04-30
DE3164498D1 (en) 1984-08-09
BG35330A3 (en) 1984-03-15
EP0034924A3 (en) 1981-12-02
FI810505L (fi) 1981-08-21
IL62118A (en) 1984-03-30
CA1147322A (en) 1983-05-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee