JPH02117700A - 生物学的に活性な蛋白質 - Google Patents
生物学的に活性な蛋白質Info
- Publication number
- JPH02117700A JPH02117700A JP1076871A JP7687189A JPH02117700A JP H02117700 A JPH02117700 A JP H02117700A JP 1076871 A JP1076871 A JP 1076871A JP 7687189 A JP7687189 A JP 7687189A JP H02117700 A JPH02117700 A JP H02117700A
- Authority
- JP
- Japan
- Prior art keywords
- protein
- inhibitor
- tnfa
- cells
- tnf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8807803.5 | 1988-03-31 | ||
| GB888807803A GB8807803D0 (en) | 1988-03-31 | 1988-03-31 | Biochemical product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH02117700A true JPH02117700A (ja) | 1990-05-02 |
Family
ID=10634493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1076871A Pending JPH02117700A (ja) | 1988-03-31 | 1989-03-30 | 生物学的に活性な蛋白質 |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPH02117700A (de) |
| KR (1) | KR890014125A (de) |
| AU (1) | AU3228789A (de) |
| BE (1) | BE1001845A4 (de) |
| DE (1) | DE3910323A1 (de) |
| DK (1) | DK156589A (de) |
| FR (1) | FR2629345A1 (de) |
| GB (2) | GB8807803D0 (de) |
| IL (1) | IL89804A0 (de) |
| IT (1) | IT1232827B (de) |
| NL (1) | NL8900779A (de) |
| SE (1) | SE8901115L (de) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03163099A (ja) * | 1989-07-18 | 1991-07-15 | Synergen Inc | 腫瘍壊死因子（ｔｎｆ）インヒビターおよびその製造方法 |
| WO1992001002A1 (fr) * | 1990-07-11 | 1992-01-23 | Teijin Limited | Inhibiteur de l'activite du facteur de la necrose tumorale et son procede de preparation |
| JPH04164099A (ja) * | 1989-09-12 | 1992-06-09 | F Hoffmann La Roche Ag | Ｔｎｆ結合タンパク質 |
| JPH06510122A (ja) * | 1991-08-23 | 1994-11-10 | エヌチップ インコーポレイテッド | パッケージされていない集積回路のバーン・イン技術 |
| KR100234520B1 (ko) * | 1991-01-18 | 1999-12-15 | 그레고리 아보트 | 종양괴사인자 매개병 치료용 의약품 조성물 |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL83878A (en) * | 1987-09-13 | 1995-07-31 | Yeda Res & Dev | Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it |
| US5811261A (en) * | 1988-09-12 | 1998-09-22 | Yeda Research And Development Co. Ltd. | Expression of the recombinant tumor necrosis factor binding protein I (TBP-I) |
| US7264944B1 (en) | 1989-04-21 | 2007-09-04 | Amgen Inc. | TNF receptors, TNF binding proteins and DNAs coding for them |
| EP0393438B1 (de) * | 1989-04-21 | 2005-02-16 | Amgen Inc. | TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs |
| US6221675B1 (en) | 1989-04-21 | 2001-04-24 | Amgen, Inc. | TNF receptors, TNF binding proteins and DNAs coding for them |
| US6143866A (en) * | 1989-07-18 | 2000-11-07 | Amgen, Inc. | Tumor necrosis factor (TNF) inhibitor and method for obtaining the same |
| US5945397A (en) * | 1989-09-05 | 1999-08-31 | Immunex Corporation | Purified p75 (type II) tumor necrosis factor receptor polypeptides |
| US5605690A (en) * | 1989-09-05 | 1997-02-25 | Immunex Corporation | Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor |
| CA2485553A1 (en) * | 1989-09-05 | 1991-03-21 | Immunex Corporation | Tumor necrosis factor - .alpha. and - .beta. receptors |
| US5395760A (en) * | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| US6552170B1 (en) | 1990-04-06 | 2003-04-22 | Amgen Inc. | PEGylation reagents and compounds formed therewith |
| US5304634A (en) * | 1990-10-12 | 1994-04-19 | Hoechst Aktiengesellschaft | Inhibitors for the formation of tumor necrosis factor |
| TW555765B (en) | 1996-07-09 | 2003-10-01 | Amgen Inc | Low molecular weight soluble tumor necrosis factor type-I and type-II proteins |
| AU5696198A (en) | 1996-12-06 | 1998-06-29 | Amgen, Inc. | Combination therapy using a tnf binding protein for treating tnf-mediated diseases |
| WO1998024477A1 (en) | 1996-12-06 | 1998-06-11 | Amgen Inc. | Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| DK2295081T3 (en) | 2001-06-26 | 2019-02-18 | Amgen Inc | Antibodies to OPGL |
| US9028822B2 (en) | 2002-06-28 | 2015-05-12 | Domantis Limited | Antagonists against TNFR1 and methods of use therefor |
| WO2004060911A2 (en) | 2002-12-30 | 2004-07-22 | Amgen Inc. | Combination therapy with co-stimulatory factors |
| US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
| TW201117824A (en) | 2009-10-12 | 2011-06-01 | Amgen Inc | Use of IL-17 receptor a antigen binding proteins |
| HUE035618T2 (en) | 2010-01-15 | 2018-05-28 | Kirin Amgen Inc | Antibody presentation and therapeutic regimens |
| US20140234330A1 (en) | 2011-07-22 | 2014-08-21 | Amgen Inc. | Il-17 receptor a is required for il-17c biology |
| CA2944605C (en) | 2014-03-31 | 2023-10-17 | Kirin-Amgen, Inc. | Methods of treating nail and scalp psoriasis |
-
1988
- 1988-03-31 GB GB888807803A patent/GB8807803D0/en active Pending
-
1989
- 1989-03-30 NL NL8900779A patent/NL8900779A/nl not_active Application Discontinuation
- 1989-03-30 GB GB8907148A patent/GB2218101A/en not_active Withdrawn
- 1989-03-30 JP JP1076871A patent/JPH02117700A/ja active Pending
- 1989-03-30 KR KR1019890004087A patent/KR890014125A/ko not_active Application Discontinuation
- 1989-03-30 SE SE8901115A patent/SE8901115L/ not_active Application Discontinuation
- 1989-03-30 IL IL89804A patent/IL89804A0/xx unknown
- 1989-03-30 AU AU32287/89A patent/AU3228789A/en not_active Abandoned
- 1989-03-30 BE BE8900350A patent/BE1001845A4/fr not_active IP Right Cessation
- 1989-03-30 FR FR8904160A patent/FR2629345A1/fr active Pending
- 1989-03-30 DK DK156589A patent/DK156589A/da not_active IP Right Cessation
- 1989-03-30 DE DE3910323A patent/DE3910323A1/de not_active Withdrawn
- 1989-03-30 IT IT8947794A patent/IT1232827B/it active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03163099A (ja) * | 1989-07-18 | 1991-07-15 | Synergen Inc | 腫瘍壊死因子（ｔｎｆ）インヒビターおよびその製造方法 |
| JPH04164099A (ja) * | 1989-09-12 | 1992-06-09 | F Hoffmann La Roche Ag | Ｔｎｆ結合タンパク質 |
| WO1992001002A1 (fr) * | 1990-07-11 | 1992-01-23 | Teijin Limited | Inhibiteur de l'activite du facteur de la necrose tumorale et son procede de preparation |
| KR100234520B1 (ko) * | 1991-01-18 | 1999-12-15 | 그레고리 아보트 | 종양괴사인자 매개병 치료용 의약품 조성물 |
| JPH06510122A (ja) * | 1991-08-23 | 1994-11-10 | エヌチップ インコーポレイテッド | パッケージされていない集積回路のバーン・イン技術 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB8807803D0 (en) | 1988-05-05 |
| KR890014125A (ko) | 1989-10-21 |
| FR2629345A1 (fr) | 1989-10-06 |
| SE8901115L (sv) | 1989-10-01 |
| SE8901115D0 (sv) | 1989-03-30 |
| DK156589D0 (da) | 1989-03-30 |
| BE1001845A4 (fr) | 1990-03-20 |
| NL8900779A (nl) | 1989-10-16 |
| GB2218101A (en) | 1989-11-08 |
| DE3910323A1 (de) | 1989-10-19 |
| IL89804A0 (en) | 1989-09-28 |
| IT1232827B (it) | 1992-03-05 |
| AU3228789A (en) | 1989-10-05 |
| IT8947794A0 (it) | 1989-03-30 |
| DK156589A (da) | 1989-10-01 |
| GB8907148D0 (en) | 1989-05-10 |
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