JP7600208B2 - 拘束された脂質を含むナノ材料およびその使用 - Google Patents
拘束された脂質を含むナノ材料およびその使用 Download PDFInfo
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- JP7600208B2 JP7600208B2 JP2022506087A JP2022506087A JP7600208B2 JP 7600208 B2 JP7600208 B2 JP 7600208B2 JP 2022506087 A JP2022506087 A JP 2022506087A JP 2022506087 A JP2022506087 A JP 2022506087A JP 7600208 B2 JP7600208 B2 JP 7600208B2
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- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
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- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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- C07C217/10—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
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| JP7883580B2 (ja) | 2021-10-08 | 2026-07-01 | スージョウ・アボジェン・バイオサイエンシズ・カンパニー・リミテッド | 脂質化合物及び脂質ナノ粒子組成物 |
| CA3241488A1 (en) | 2021-12-20 | 2023-06-29 | Beam Therapeutics Inc. | Ionizable amine lipids and lipid nanoparticles |
| WO2023121971A1 (en) | 2021-12-20 | 2023-06-29 | Beam Therapeutics Inc. | Nanomaterials comprising tetravalent lipid compounds |
| EP4540222A1 (en) | 2022-07-20 | 2025-04-23 | Beam Therapeutics Inc. | Nanomaterials comprising triols |
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2020
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- 2020-07-24 KR KR1020227006660A patent/KR20220040484A/ko not_active Ceased
- 2020-07-24 WO PCT/US2020/043512 patent/WO2021021634A1/en not_active Ceased
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- 2020-07-24 US US17/630,861 patent/US12569438B2/en active Active
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015095340A1 (en) | 2013-12-19 | 2015-06-25 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| WO2017173054A1 (en) | 2016-03-30 | 2017-10-05 | Intellia Therapeutics, Inc. | Lipid nanoparticle formulations for crispr/cas components |
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| JP2022542389A (ja) | 2022-10-03 |
| EP4003967A1 (en) | 2022-06-01 |
| CA3145913A1 (en) | 2021-02-04 |
| AU2020323897A1 (en) | 2022-02-24 |
| US12569438B2 (en) | 2026-03-10 |
| WO2021021634A1 (en) | 2021-02-04 |
| KR20220040484A (ko) | 2022-03-30 |
| US20220273566A1 (en) | 2022-09-01 |
| EP4003967A4 (en) | 2024-01-17 |
| US20260232587A1 (en) | 2026-08-13 |
| CN114502542A (zh) | 2022-05-13 |
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