JP2022542389A5 - - Google Patents
Info
- Publication number
- JP2022542389A5 JP2022542389A5 JP2022506087A JP2022506087A JP2022542389A5 JP 2022542389 A5 JP2022542389 A5 JP 2022542389A5 JP 2022506087 A JP2022506087 A JP 2022506087A JP 2022506087 A JP2022506087 A JP 2022506087A JP 2022542389 A5 JP2022542389 A5 JP 2022542389A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- lipid
- nanoparticle composition
- lipid nanoparticle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962879731P | 2019-07-29 | 2019-07-29 | |
| US62/879,731 | 2019-07-29 | ||
| PCT/US2020/043512 WO2021021634A1 (en) | 2019-07-29 | 2020-07-24 | Nanomaterials containing constrained lipids and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022542389A JP2022542389A (ja) | 2022-10-03 |
| JP2022542389A5 true JP2022542389A5 (enExample) | 2023-07-21 |
| JP7600208B2 JP7600208B2 (ja) | 2024-12-16 |
Family
ID=74228270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506087A Active JP7600208B2 (ja) | 2019-07-29 | 2020-07-24 | 拘束された脂質を含むナノ材料およびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12569438B2 (enExample) |
| EP (1) | EP4003967A4 (enExample) |
| JP (1) | JP7600208B2 (enExample) |
| KR (1) | KR20220040484A (enExample) |
| CN (1) | CN114502542A (enExample) |
| AU (1) | AU2020323897A1 (enExample) |
| CA (1) | CA3145913A1 (enExample) |
| WO (1) | WO2021021634A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201707569YA (en) | 2012-12-12 | 2017-10-30 | Broad Inst Inc | Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications |
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| WO2014204725A1 (en) | 2013-06-17 | 2014-12-24 | The Broad Institute Inc. | Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation |
| WO2015089419A2 (en) * | 2013-12-12 | 2015-06-18 | The Broad Institute Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components |
| KR20160097338A (ko) | 2013-12-12 | 2016-08-17 | 더 브로드 인스티튜트, 인코퍼레이티드 | 뉴클레오티드 반복 장애에서의 ｃｒｉｓｐｒ-ｃａｓ 시스템의 조성물 및 방법 및 용도 |
| CN105899658B (zh) | 2013-12-12 | 2020-02-18 | 布罗德研究所有限公司 | 针对hbv和病毒性疾病以及障碍的crispr-cas系统和组合物的递送、用途和治疗应用 |
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| JP7600208B2 (ja) | 2019-07-29 | 2024-12-16 | ジョージア テック リサーチ コーポレイション | 拘束された脂質を含むナノ材料およびその使用 |
| JP7699128B2 (ja) * | 2019-12-06 | 2025-06-26 | ガイド セラピューティクス，エルエルシー | ナノマテリアル |
| CN115175894B (zh) | 2020-01-09 | 2024-09-06 | 盖德治疗有限责任公司 | 纳米材料 |
| CZ310613B6 (cs) | 2020-09-23 | 2026-01-28 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Lipidoidy pro transfekci nukleových kyselin a jejich použití |
| CN116761888A (zh) | 2021-01-20 | 2023-09-15 | 比姆医疗股份有限公司 | 纳米材料 |
| EP4281080A4 (en) | 2021-01-20 | 2025-09-24 | Beam Therapeutics Inc | NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT |
| EP4322920A1 (en) * | 2021-04-17 | 2024-02-21 | Intellia Therapeutics, Inc. | Lipid nanoparticle compositions |
| CZ310443B6 (cs) | 2021-07-19 | 2025-06-25 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití |
| CN113637708B (zh) * | 2021-08-09 | 2023-07-25 | 中国科学院过程工程研究所 | 一种CRISPR-cas9基因编辑系统递送载体及其制备方法和应用 |
| WO2023044343A1 (en) | 2021-09-14 | 2023-03-23 | Renagade Therapeutics Management Inc. | Acyclic lipids and methods of use thereof |
| TW202328067A (zh) | 2021-09-14 | 2023-07-16 | 美商雷納嘉德醫療管理公司 | 環狀脂質及其使用方法 |
| WO2023121971A1 (en) * | 2021-12-20 | 2023-06-29 | Beam Therapeutics Inc. | Nanomaterials comprising tetravalent lipid compounds |
| WO2023122611A1 (en) * | 2021-12-23 | 2023-06-29 | Georgia Tech Research Corporation | Ionizable lipids with bioactive motifs |
| US20250387490A9 (en) * | 2022-01-04 | 2025-12-25 | Massachusetts Institute Of Technology | Ionizable lipids for multiple organ targeting |
| CN114436994B (zh) * | 2022-01-26 | 2024-02-27 | 中国药科大学 | 金刚烷尾链脂质及其在细胞转染中的应用 |
| WO2023230601A1 (en) | 2022-05-27 | 2023-11-30 | Beam Therapeutics Inc. | Identification of nanoparticles for preferential tissue or cell targeting |
| WO2024006960A1 (en) * | 2022-06-29 | 2024-01-04 | Juno Therapeutics, Inc. | Lipid nanoparticles for delivery of nucleic acids |
| EP4540222A1 (en) | 2022-07-20 | 2025-04-23 | Beam Therapeutics Inc. | Nanomaterials comprising triols |
| WO2024081639A1 (en) * | 2022-10-11 | 2024-04-18 | Seawolf Therapeutics, Inc. | Novel lipid nanoparticle compositions for the delivery of nucleic acids |
| TW202428289A (zh) | 2022-11-08 | 2024-07-16 | 美商歐納醫療公司 | 環狀rna組合物 |
| CN118125932A (zh) * | 2022-11-27 | 2024-06-04 | 北京启辰生生物科技有限公司 | 一种可电离脂质分子及其纳米颗粒组合物在核酸递送中的应用 |
| CN115925563B (zh) * | 2023-02-28 | 2023-05-16 | 清华大学 | 一种可用于靶向肺部递送核酸的脂质分子及其制备方法与应用 |
| CN116199646B (zh) * | 2023-03-07 | 2024-01-26 | 山东大学 | 一种基于Tris的可电离脂质及其制备方法与应用 |
| WO2024233308A2 (en) | 2023-05-05 | 2024-11-14 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| WO2025007148A1 (en) | 2023-06-30 | 2025-01-02 | Orna Therapeutics, Inc. | Polymer lipid nanoparticle compositions for delivering circular polynucleotides |
| WO2025049690A1 (en) | 2023-08-29 | 2025-03-06 | Orna Therapeutics, Inc. | Circular polyethylene glycol lipids |
| KR20250036032A (ko) * | 2023-09-05 | 2025-03-13 | 한국생명공학연구원 | 지질 나노 입자를 이용한 핵산 전달 시스템 |
| CN122497525A (zh) | 2023-11-07 | 2026-07-31 | 欧纳医疗公司 | 环状rna组合物 |
| WO2025117969A1 (en) | 2023-12-01 | 2025-06-05 | Orna Therapeutics, Inc. | Process for manufacturing lipid nanoparticles |
| WO2025128871A2 (en) | 2023-12-13 | 2025-06-19 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025147545A1 (en) * | 2024-01-03 | 2025-07-10 | Juno Therapeutics, Inc. | Lipid nanoparticles for delivery of nucleic acids and related methods and uses |
| WO2025166238A1 (en) | 2024-01-31 | 2025-08-07 | Orna Therapeutics, Inc. | Fast-shedding polyethylene glycol lipids |
| WO2025250751A1 (en) | 2024-05-31 | 2025-12-04 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| WO2026122685A1 (en) | 2024-12-03 | 2026-06-11 | Orna Therapeutics, Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
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| NL257307A (enExample) | 1959-10-28 | |||
| US3686238A (en) | 1970-01-19 | 1972-08-22 | Syntex Corp | Glycerol esterified with 2-naphthyl-acetic acids and fatty acids |
| EP1021549A2 (en) | 1997-09-19 | 2000-07-26 | Sequitur, Inc. | SENSE mRNA THERAPY |
| EP1164125A4 (en) | 1999-11-08 | 2005-05-04 | Daicel Chem | ADAMANTANE DERIVATIVES AND PROCESS FOR PREPARING |
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| WO2003101952A2 (en) | 2002-05-31 | 2003-12-11 | The Regents Of The University Of California | Polyamine-mediated transfection |
| JP2005181734A (ja) | 2003-12-19 | 2005-07-07 | Fuji Photo Film Co Ltd | 画像記録材料 |
| DE102007029471A1 (de) | 2007-06-20 | 2008-12-24 | Novosom Ag | Neue fakultativ kationische Sterole |
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| WO2016187531A1 (en) | 2015-05-21 | 2016-11-24 | Ohio State Innovation Foundation | Benzene-1,3,5-tricarboxamide derivatives and uses thereof |
| HRP20220156T1 (hr) | 2015-09-17 | 2022-04-15 | Modernatx, Inc. | Spojevi i pripravci za unutarstaničnu isporuku terapeutskih sredstava |
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| ES3030658T3 (en) * | 2016-03-30 | 2025-07-01 | Intellia Therapeutics Inc | Lipid nanoparticle formulations for crispr/cas components |
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| US11622942B2 (en) | 2017-11-14 | 2023-04-11 | Ohio State Innovation Foundation | Benzene-1,3,5-tricarboxamide derived ester lipids and uses thereof |
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| EP3911302B1 (en) | 2019-01-17 | 2025-09-10 | Georgia Tech Research Corporation | Drug delivery systems containing oxidized cholesterols |
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| US20220233459A1 (en) | 2019-06-05 | 2022-07-28 | Guide Therapeutics, Inc. | Analysis of materials for tissue delivery |
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| JP2022552724A (ja) | 2019-10-21 | 2022-12-19 | フラスクワークス， エルエルシー | 細胞培養のためのシステムおよび方法 |
| JP7699128B2 (ja) | 2019-12-06 | 2025-06-26 | ガイド セラピューティクス，エルエルシー | ナノマテリアル |
| CN115175894B (zh) | 2020-01-09 | 2024-09-06 | 盖德治疗有限责任公司 | 纳米材料 |
| EP4262817A4 (en) | 2020-12-21 | 2025-03-12 | Beam Therapeutics Inc. | NANOMATERIALS WITH ACETALS |
| JP2024505327A (ja) | 2020-12-21 | 2024-02-06 | ビーム セラピューティクス インク． | 炭酸塩を含むナノ材料 |
| JP2024508347A (ja) | 2020-12-21 | 2024-02-27 | ビーム セラピューティクス インク． | エステル結合アセタールを含むナノ材料 |
| EP4281080A4 (en) | 2021-01-20 | 2025-09-24 | Beam Therapeutics Inc | NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT |
| CN116761888A (zh) | 2021-01-20 | 2023-09-15 | 比姆医疗股份有限公司 | 纳米材料 |
| CA3203741A1 (en) | 2021-01-20 | 2022-07-28 | Beam Therapeutics Inc. | Nanomaterials comprising an ionizable lipid |
| AU2022210299A1 (en) | 2021-01-20 | 2023-06-29 | Beam Therapeutics Inc. | Ionizable lipids for nanomaterials |
| WO2022251665A1 (en) | 2021-05-28 | 2022-12-01 | Renagade Therapeutics Management Inc. | Lipid nanoparticles and methods of use thereof |
| JP7883580B2 (ja) | 2021-10-08 | 2026-07-01 | スージョウ・アボジェン・バイオサイエンシズ・カンパニー・リミテッド | 脂質化合物及び脂質ナノ粒子組成物 |
| CA3241488A1 (en) | 2021-12-20 | 2023-06-29 | Beam Therapeutics Inc. | Ionizable amine lipids and lipid nanoparticles |
| WO2023121971A1 (en) | 2021-12-20 | 2023-06-29 | Beam Therapeutics Inc. | Nanomaterials comprising tetravalent lipid compounds |
| EP4540222A1 (en) | 2022-07-20 | 2025-04-23 | Beam Therapeutics Inc. | Nanomaterials comprising triols |
-
2020
- 2020-07-24 JP JP2022506087A patent/JP7600208B2/ja active Active
- 2020-07-24 KR KR1020227006660A patent/KR20220040484A/ko not_active Ceased
- 2020-07-24 WO PCT/US2020/043512 patent/WO2021021634A1/en not_active Ceased
- 2020-07-24 EP EP20846355.4A patent/EP4003967A4/en active Pending
- 2020-07-24 US US17/630,861 patent/US12569438B2/en active Active
- 2020-07-24 CA CA3145913A patent/CA3145913A1/en active Pending
- 2020-07-24 CN CN202080068505.5A patent/CN114502542A/zh not_active Withdrawn
- 2020-07-24 AU AU2020323897A patent/AU2020323897A1/en not_active Abandoned
-
2026
- 2026-02-03 US US19/468,212 patent/US20260232587A1/en active Pending
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