JP2022530018A5 - - Google Patents

Info

Publication number
JP2022530018A5
JP2022530018A5 JP2021562869A JP2021562869A JP2022530018A5 JP 2022530018 A5 JP2022530018 A5 JP 2022530018A5 JP 2021562869 A JP2021562869 A JP 2021562869A JP 2021562869 A JP2021562869 A JP 2021562869A JP 2022530018 A5 JP2022530018 A5 JP 2022530018A5
Authority
JP
Japan
Prior art keywords
lipid
nanoparticle according
anchor portion
peg
lipid nanoparticle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2021562869A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022530018A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/029907 external-priority patent/WO2020219941A1/en
Publication of JP2022530018A publication Critical patent/JP2022530018A/ja
Publication of JP2022530018A5 publication Critical patent/JP2022530018A5/ja
Abandoned legal-status Critical Current

Links

JP2021562869A 2019-04-26 2020-04-24 脂質ナノ粒子 Abandoned JP2022530018A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962839452P 2019-04-26 2019-04-26
US62/839,452 2019-04-26
US201962867098P 2019-06-26 2019-06-26
US62/867,098 2019-06-26
PCT/US2020/029907 WO2020219941A1 (en) 2019-04-26 2020-04-24 Lipid nanoparticles

Publications (2)

Publication Number Publication Date
JP2022530018A JP2022530018A (ja) 2022-06-27
JP2022530018A5 true JP2022530018A5 (enExample) 2023-04-27

Family

ID=72941858

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021562869A Abandoned JP2022530018A (ja) 2019-04-26 2020-04-24 脂質ナノ粒子

Country Status (8)

Country Link
US (1) US20220168222A1 (enExample)
EP (1) EP3959314A4 (enExample)
JP (1) JP2022530018A (enExample)
CN (1) CN114026233A (enExample)
AU (1) AU2020262437A1 (enExample)
CA (1) CA3137450A1 (enExample)
MA (1) MA55766A (enExample)
WO (1) WO2020219941A1 (enExample)

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AU2019376006B2 (en) * 2018-11-09 2026-07-02 Arbutus Biopharma Corporation Cationic lipids containing silicon
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US12023376B1 (en) 2020-04-17 2024-07-02 Triad National Security, Llc Conserved region T cell vaccines for coronavirus and methods of use
MX2023000511A (es) * 2020-07-10 2023-02-13 Genevant Sciences Gmbh Nanoparticulas lipidicas para administrar agentes terapeuticos en los pulmones.
MX2023001109A (es) 2020-07-27 2023-04-24 Anjarium Biosciences Ag Composiciones de moleculas de adn, metodos para elaborar las mismas, y metodos de usos de las mismas.
CZ310613B6 (cs) 2020-09-23 2026-01-28 Ústav organické chemie a biochemie AV ČR, v. v. i. Lipidoidy pro transfekci nukleových kyselin a jejich použití
MX2023004371A (es) 2020-10-14 2023-07-26 George Mason Res Foundation Inc Lípidos ionizables, y métodos de fabricación y uso de los mismos.
WO2022099003A1 (en) 2020-11-06 2022-05-12 Sanofi Lipid nanoparticles for delivering mrna vaccines
CN117098541A (zh) 2020-11-25 2023-11-21 阿卡格拉医药公司 用于递送核酸的脂质纳米粒及相关使用方法
AU2021403156A1 (en) * 2020-12-18 2023-07-13 Genevant Sciences Gmbh Peg lipids and lipid nanoparticles
WO2022198229A1 (en) * 2021-03-17 2022-09-22 Board Of Regents Of The University Of Nebraska Lipid nanoparticle formulations and methods of use thereof
CN117203340A (zh) 2021-04-16 2023-12-08 基因泰克公司 优化的tlr7配体及其用途
CZ310443B6 (cs) 2021-07-19 2025-06-25 Ústav organické chemie a biochemie AV ČR, v. v. i. Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití
IL309502A (en) 2021-09-03 2024-02-01 CureVac SE Lipid nanoparticles for nucleic acid delivery involving phosphatidylserine
WO2023069948A1 (en) 2021-10-18 2023-04-27 Flagship Pioneering Innovations Vii, Llc Dna compositions and related methods
KR20230061895A (ko) * 2021-10-29 2023-05-09 주식회사 아이큐어비앤피 지질 나노입자 및 세포 투과성을 갖는 신규 펩타이드의 복합체
WO2023216232A1 (zh) * 2022-05-13 2023-11-16 南方科技大学 一种含有二硫键的脂质化合物及其组合物
AU2023268051A1 (en) 2022-05-13 2025-01-02 BioNTech SE Rna compositions targeting hiv
WO2023230098A1 (en) 2022-05-23 2023-11-30 Logicbio Therapeutics, Inc. Gene therapy compositions and methods of use thereof
WO2023230295A1 (en) 2022-05-25 2023-11-30 BioNTech SE Rna compositions for delivery of monkeypox antigens and related methods
WO2023230587A2 (en) 2022-05-25 2023-11-30 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
US20250375534A1 (en) 2022-05-30 2025-12-11 BioNTech SE Complexes for delivery of nucleic acids
TWI858802B (zh) * 2022-07-06 2024-10-11 南韓商綠十字股份有限公司 使用陽離子膽固醇用於核酸遞送的局部遞送的脂質納米顆粒
CN119677852A (zh) 2022-07-29 2025-03-21 麻省理工学院 抑制信号调节蛋白α(SIRPα)基因表达的组合物和方法
WO2024037577A1 (en) * 2022-08-18 2024-02-22 Suzhou Abogen Biosciences Co., Ltd. Composition of lipid nanoparticles
WO2024057237A1 (en) 2022-09-16 2024-03-21 Pfizer Inc. Lipid nanoparticles
EP4342460A1 (en) 2022-09-21 2024-03-27 NovoArc GmbH Lipid nanoparticle with nucleic acid cargo
US20240108545A1 (en) 2022-10-03 2024-04-04 West Pharmaceutical Services, Inc. Methods and adapters for mixing pharmaceutical complexes
CN119095585A (zh) * 2022-12-21 2024-12-06 苏州艾博生物科技有限公司 包含固醇修饰的磷脂的脂质纳米颗粒
CN121127490A (zh) 2022-12-28 2025-12-12 生物技术欧洲股份公司 靶向hiv的rna组合物
EP4410316A1 (en) * 2023-02-01 2024-08-07 4basebio UK Ltd Nanoparticles for delivery of nucleic acid cargos
EP4661843A2 (en) * 2023-02-06 2025-12-17 University of Tennessee Research Foundation Multi-functional lipid nanoparticles and uses thereof
WO2024205499A1 (en) * 2023-03-27 2024-10-03 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound and related methods thereof
WO2024259158A2 (en) * 2023-06-13 2024-12-19 Cornell University Lipid nanoparticles for peptide delivery and methods of making and using the same
EP4754130A2 (en) 2023-08-03 2026-06-10 BioNTech SE Rna compositions targeting hiv
CN121866336A (zh) 2023-08-03 2026-04-14 百欧恩泰欧洲股份公司 靶向hiv的rna组合物
KR20260065891A (ko) 2023-09-01 2026-05-11 노보아크 게엠베하 핵산 카고 및 이온화가능한 지질을 갖는 지질 나노입자
WO2025124711A1 (en) 2023-12-13 2025-06-19 BioNTech SE Glycolipid compositions
WO2025219570A1 (en) 2024-04-17 2025-10-23 Johannes Kepler Universität Linz Composition for inhibiting protein translocation and methods using the same
WO2025242657A1 (en) 2024-05-21 2025-11-27 Shape Biopharmaceuticals Ag Lipopeptide building blocks and aggregates
GB202408360D0 (en) 2024-06-11 2024-07-24 Cancer Research Tech Ltd Tumour sensitisation
WO2026119908A1 (en) 2024-12-05 2026-06-11 Merck Patent Gmbh Helper lipids in nucleic acid delivery

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DK3386484T3 (da) * 2015-12-10 2022-07-04 Modernatx Inc Sammensætninger og fremgangsmåder til afgivelse af terapeutiske midler
US11191849B2 (en) * 2016-06-30 2021-12-07 Arbutus Biopharma Corporation Compositions and methods for delivering messenger RNA

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