JP7512433B2 - 抗ｐｄ－１抗体 - Google Patents

抗ｐｄ－１抗体 Download PDF

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JP7512433B2
JP7512433B2 JP2022572362A JP2022572362A JP7512433B2 JP 7512433 B2 JP7512433 B2 JP 7512433B2 JP 2022572362 A JP2022572362 A JP 2022572362A JP 2022572362 A JP2022572362 A JP 2022572362A JP 7512433 B2 JP7512433 B2 JP 7512433B2
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antibody
seq
amino acid
disease
acid sequence
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JP2023528778A5 (https=
JP2023528778A (ja
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ブレア，デイビッド・エー
ガラファ，ニコル・ケー
グプタ，パンカジ
グプタ，プリヤンカー
ハン，フェイ
カルラック，アーロン・ティモシー
リウ，ドンメイ
ロレンツ，アイヴォ
ンボウ，ムアマドゥ・ラミン
モレノ－ガルシア，ミゲル・イー
モッツィエルツ，ヨーゼフ・エー
ラルフ，ケリー・エル・エム
シャアバン，アブドゥルサラム
ホワイト，デラ・エム
ウー，ヘレン・ハイシャ
ヤン，グアンウェイ
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2022572362A 2020-05-26 2021-05-24 抗ｐｄ－１抗体 Active JP7512433B2 (ja)

Priority Applications (1)

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JP2024102704A JP7777632B2 (ja) 2020-05-26 2024-06-26 抗ｐｄ－１抗体

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US202063029962P 2020-05-26 2020-05-26
US63/029,962 2020-05-26
US202063039686P 2020-06-16 2020-06-16
US63/039,686 2020-06-16
PCT/US2021/033823 WO2021242663A1 (en) 2020-05-26 2021-05-24 Anti-pd-1 antibodies

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JP2023528778A JP2023528778A (ja) 2023-07-06
JP2023528778A5 JP2023528778A5 (https=) 2024-02-02
JP7512433B2 true JP7512433B2 (ja) 2024-07-08

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EP (2) EP4157876B1 (https=)
JP (2) JP7512433B2 (https=)
KR (1) KR102871588B1 (https=)
CN (3) CN115956087B (https=)
AU (1) AU2021280232B2 (https=)
BR (1) BR112022023989A2 (https=)
CA (1) CA3181776A1 (https=)
CL (1) CL2022003304A1 (https=)
CO (1) CO2022018416A2 (https=)
CR (1) CR20220596A (https=)
DK (1) DK4157876T3 (https=)
DO (1) DOP2022000264A (https=)
EC (1) ECSP22092185A (https=)
ES (1) ES2994127T3 (https=)
FI (1) FI4157876T3 (https=)
HR (1) HRP20241488T1 (https=)
HU (1) HUE069403T2 (https=)
IL (1) IL298431A (https=)
JO (1) JOP20220320B1 (https=)
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MA (1) MA59827B1 (https=)
MX (1) MX2022014974A (https=)
PE (1) PE20231076A1 (https=)
PH (1) PH12022553181A1 (https=)
PL (1) PL4157876T3 (https=)
PT (1) PT4157876T (https=)
RS (1) RS66193B1 (https=)
SI (1) SI4157876T1 (https=)
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Publication number Priority date Publication date Assignee Title
CR20220596A (es) 2020-05-26 2023-01-23 Boehringer Ingelheim Int Anticuerpos anti-pd-1
IL308258A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
KR20240137086A (ko) * 2022-01-28 2024-09-19 조지아뮨 인코포레이티드 Pd-1 작용제인 세포예정사 단백질 1에 대한 항체
WO2026008665A1 (en) * 2024-07-01 2026-01-08 Vib Vzw Binders of the pd-1•pd-l1 complex and their use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013521769A (ja) 2010-03-11 2013-06-13 ユセベ ファルマ ソシエテ アノニム 生物学的製剤：ヒト化アゴニスト抗ｐｄ−１抗体
JP2013542194A (ja) 2010-09-27 2013-11-21 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 抗ｃｄ４８抗体およびその使用

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