JP7505980B2 - C3b結合ポリペプチド - Google Patents
C3b結合ポリペプチド Download PDFInfo
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- JP7505980B2 JP7505980B2 JP2020538949A JP2020538949A JP7505980B2 JP 7505980 B2 JP7505980 B2 JP 7505980B2 JP 2020538949 A JP2020538949 A JP 2020538949A JP 2020538949 A JP2020538949 A JP 2020538949A JP 7505980 B2 JP7505980 B2 JP 7505980B2
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| GB201821082D0 (en) * | 2018-12-21 | 2019-02-06 | Gyroscope Therapeutics Ltd | Combination of complement factors i and h, and vector encoding thereof |
| EP4048318A4 (en) * | 2019-10-23 | 2023-11-22 | Gemini Therapeutics Sub, Inc. | METHOD FOR TREATING PATIENTS WITH CFH MUTATIONS USING RECOMBINANT CFH PROTEINS |
| GB202006789D0 (en) | 2020-05-07 | 2020-06-24 | Univ Manchester | Detection of complement proteins |
| WO2022058447A1 (en) | 2020-09-16 | 2022-03-24 | The University Of Manchester | Complementome assay |
| GB202107586D0 (en) | 2021-05-27 | 2021-07-14 | Complement Therapeutics Ltd | Inhibitory nucleic acids for Factor H family proteins |
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Citations (6)
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| JP2011503024A (ja) | 2007-11-02 | 2011-01-27 | ノバルティス アーゲー | 補体成分を調節するための分子および方法 |
| JP2011504872A (ja) | 2007-06-07 | 2011-02-17 | ジェネンテック, インコーポレイテッド | 補体が関係している障害の予防および処置のためのc3b抗体ならびに方法 |
| JP2015500811A (ja) | 2011-12-01 | 2015-01-08 | プロテボビオ, インコーポレイテッド | 補体経路およびvegf経路に対するタンパク質インヒビターおよびそれらの使用方法 |
| WO2017194912A1 (en) | 2016-05-09 | 2017-11-16 | Cambridge Enterprise Limited | Treatment of complement-mediated disorders |
| WO2018002131A1 (en) | 2016-06-28 | 2018-01-04 | Universität Ulm | Complement inhibitors and uses thereof |
| JP7341897B2 (ja) | 2017-06-09 | 2023-09-11 | コンプリメント・セラピューティクス・リミテッド | C3b不活性化ポリペプチド |
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| US5981481A (en) | 1974-12-06 | 1999-11-09 | The Johns Hopkins University | Human C3b/C4b receptor (CR1) |
| JPH0742235B2 (ja) | 1985-11-08 | 1995-05-10 | 三共株式会社 | 自己免疫性疾病の予防・治療剤 |
| DE3600368C1 (de) | 1986-01-09 | 1987-04-02 | Goldschmidt Ag Th | Trennmittel fuer Polyurethanformteile |
| IL89790A (en) | 1988-04-01 | 2002-05-23 | Johns Hopking University | Nucleic acid sequences that encode and cells that produce cr1 protein and methods of production and purification |
| US6458360B1 (en) | 1990-04-25 | 2002-10-01 | The Johns Hopkins University | Soluble complement regulatory molecules |
| WO1992010205A1 (en) | 1990-12-06 | 1992-06-25 | T Cell Sciences, Inc. | Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity |
| US5833989A (en) | 1992-06-24 | 1998-11-10 | Adprotech Plc | Soluble CR1 derivatives |
| GB9301289D0 (en) | 1993-01-22 | 1993-03-17 | Smithkline Beecham Plc | Novel composition |
| US5679546A (en) | 1993-09-24 | 1997-10-21 | Cytomed, Inc. | Chimeric proteins which block complement activation |
| US5648244A (en) | 1993-09-27 | 1997-07-15 | President And Fellows Of Harvard College | Production, purification, cleavage and use of fusion peptides |
| WO1999044625A1 (en) | 1998-03-03 | 1999-09-10 | John Hopkins University | Smallpox inhibitor of complement enzymes (spice) protein and methods of inhibiting complement activation |
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