JP7458785B2 - ヒドロキシステロイド17-βデヒドロゲナーゼ13(HSD17B13)バリアント及びその使用 - Google Patents
ヒドロキシステロイド17-βデヒドロゲナーゼ13(HSD17B13)バリアント及びその使用 Download PDFInfo
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- JP7458785B2 JP7458785B2 JP2019539795A JP2019539795A JP7458785B2 JP 7458785 B2 JP7458785 B2 JP 7458785B2 JP 2019539795 A JP2019539795 A JP 2019539795A JP 2019539795 A JP2019539795 A JP 2019539795A JP 7458785 B2 JP7458785 B2 JP 7458785B2
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| JP2025117051A JP2025160237A (ja) | 2017-01-23 | 2025-07-11 | ヒドロキシステロイド17-βデヒドロゲナーゼ13(HSD17B13)バリアント及びその使用 |
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| KR20240125690A (ko) | 2017-10-11 | 2024-08-19 | 리제너론 파마슈티칼스 인코포레이티드 | Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해 |
| WO2019183329A1 (en) * | 2018-03-21 | 2019-09-26 | Ionis Pharmaceuticals, Inc. | Modulation of hsd17b13 expression |
| US12359201B2 (en) * | 2018-03-21 | 2025-07-15 | Regeneron Pharmaceuticals, Inc. | 17ß-hydroxysteroid dehydrogenase type 13 (HSD17B13) iRNA compositions and methods of use thereof |
| WO2019204766A1 (en) | 2018-04-19 | 2019-10-24 | The Regents Of The University Of California | Compositions and methods for gene editing |
| WO2020061177A1 (en) * | 2018-09-19 | 2020-03-26 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for inhibiting expression of 17beta-hsd type 13- (hsd17b13), compositions thereof, and methods of use |
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