JP7427252B2 - 脊髄性筋萎縮症の予防または治療剤 - Google Patents

脊髄性筋萎縮症の予防または治療剤 Download PDF

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JP7427252B2
JP7427252B2 JP2020527663A JP2020527663A JP7427252B2 JP 7427252 B2 JP7427252 B2 JP 7427252B2 JP 2020527663 A JP2020527663 A JP 2020527663A JP 2020527663 A JP2020527663 A JP 2020527663A JP 7427252 B2 JP7427252 B2 JP 7427252B2
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JPWO2020004594A1 (ja
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晃嗣 富士
健 山崎
俊也 鈴木
宏司 小野
洋希 高萩
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REBORNA BIOSCIENCES, INC.
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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JP2020527663A 2018-06-27 2019-06-27 脊髄性筋萎縮症の予防または治療剤 Active JP7427252B2 (ja)

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JP2018122551 2018-06-27
JP2018122551 2018-06-27
PCT/JP2019/025732 WO2020004594A1 (fr) 2018-06-27 2019-06-27 Agent prophylactique ou thérapeutique pour amyotrophie spinale

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JPWO2020004594A1 JPWO2020004594A1 (ja) 2021-07-15
JP7427252B2 true JP7427252B2 (ja) 2024-02-05

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US (1) US12012410B2 (fr)
EP (1) EP3816160A4 (fr)
JP (1) JP7427252B2 (fr)
KR (1) KR20210025625A (fr)
CN (1) CN112469707B (fr)
AU (2) AU2019293757B2 (fr)
BR (1) BR112020026637A2 (fr)
CA (1) CA3105174A1 (fr)
CL (1) CL2020003386A1 (fr)
CO (1) CO2021000808A2 (fr)
CR (1) CR20210050A (fr)
EA (1) EA202190116A1 (fr)
IL (1) IL279786A (fr)
JO (1) JOP20200338A1 (fr)
MX (1) MX2020014116A (fr)
PE (1) PE20211585A1 (fr)
PH (1) PH12020552263A1 (fr)
SG (1) SG11202013088YA (fr)
WO (1) WO2020004594A1 (fr)

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EP3689863A1 (fr) 2017-08-04 2020-08-05 Skyhawk Therapeutics, Inc. Procédés et compositions de modulation d'épissage
WO2020006018A1 (fr) 2018-06-27 2020-01-02 Bristol-Myers Squibb Company Composés de naphtyridinone substitués utiles en tant qu'activateurs de lymphocytes t
US20220089609A1 (en) * 2018-07-26 2022-03-24 Domain Therapeutics Substituted quinazolinone derivatives and their use as positive allosteric modulators of mglur4
CA3169709A1 (fr) * 2020-02-28 2021-09-02 Remix Therapeutics Inc. Amides heterocycliques et leur utilisation pour moduler l'epissage
MX2022012676A (es) * 2020-04-08 2023-01-11 Remix Therapeutics Inc Compuestos y metodos para modular el empalme.
WO2021207554A1 (fr) * 2020-04-08 2021-10-14 Remix Therapeutics Inc. Composés et procédés de modulation de l'épissage
JP2023532332A (ja) 2020-07-02 2023-07-27 リミックス セラピューティクス インコーポレイテッド 核酸のスプライシング及び増殖性疾患の処置のためのモジュレーターとしての２－（インダゾール－５－イル）－６－（ピペリジン－４－イル）－１，７－ナフチリジン誘導体及び関連する化合物
KR20230118067A (ko) 2020-07-02 2023-08-10 레믹스 테라퓨틱스 인크. 5-[5-(피페리딘-4-일)티에노[3,2-c]피라졸-2-일]인다졸 유도체, 및 핵산 스플라이싱의 조절제로서의 및 증식성 질환의 치료를 위한 관련 화합물
CN112028896A (zh) * 2020-10-14 2020-12-04 奥锐特药业(天津)有限公司 阿卡替尼的新晶型及其制备方法
WO2023064880A1 (fr) * 2021-10-13 2023-04-20 Remix Therapeutics Inc. Composés et procédés de modulation de l'épissage d'acides nucléiques
TW202330552A (zh) 2021-10-13 2023-08-01 美商雷密克斯醫療公司 調節剪接之化合物及方法
WO2023133217A1 (fr) 2022-01-05 2023-07-13 Remix Therapeutics Inc. Dérivés de 2-(indazol-5-yl)-6-(pipéridin-4-yl)-1,7-naphtyridine et composés associés utiles comme modulateurs pour l'épissage d'acides nucléiques et pour le traitement de maladies prolifératives
WO2023133229A2 (fr) 2022-01-05 2023-07-13 Remix Therapeutics Inc. Composés et procédés de modulation d'épissage
WO2023133225A1 (fr) 2022-01-05 2023-07-13 Remix Therapeutics Inc. Composés et procédés de modulation d'épissage

Citations (12)

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