JP7421338B2 - 免疫調節融合タンパク質 - Google Patents

免疫調節融合タンパク質 Download PDF

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JP7421338B2
JP7421338B2 JP2019516603A JP2019516603A JP7421338B2 JP 7421338 B2 JP7421338 B2 JP 7421338B2 JP 2019516603 A JP2019516603 A JP 2019516603A JP 2019516603 A JP2019516603 A JP 2019516603A JP 7421338 B2 JP7421338 B2 JP 7421338B2
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cancer
fusion protein
expression vector
certain embodiments
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JP2019531728A (ja
JP2019531728A5 (OSRAM
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ラーソン，クリストファー
リード，トニー
オロンスキー，ブライアン，ティー．
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エピセントアールエックス，インコーポレイテッド
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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JP2019516603A 2016-09-27 2017-09-27 免疫調節融合タンパク質 Active JP7421338B2 (ja)

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US201662400338P 2016-09-27 2016-09-27
US62/400,338 2016-09-27
US201762484841P 2017-04-12 2017-04-12
US62/484,841 2017-04-12
PCT/US2017/053765 WO2018064190A1 (en) 2016-09-27 2017-09-27 Immunomodulatory fusion proteins

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JP2019531728A JP2019531728A (ja) 2019-11-07
JP2019531728A5 JP2019531728A5 (OSRAM) 2020-11-12
JP7421338B2 true JP7421338B2 (ja) 2024-01-24

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US (3) US10906957B2 (OSRAM)
EP (1) EP3519442A4 (OSRAM)
JP (2) JP7421338B2 (OSRAM)
KR (2) KR20240014617A (OSRAM)
CN (2) CN118307682A (OSRAM)
AU (1) AU2017336546C1 (OSRAM)
BR (1) BR112019005964A2 (OSRAM)
CA (1) CA3038526A1 (OSRAM)
IL (1) IL265657A (OSRAM)
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