JP7405991B2 - ウリジン５’－二リン酸（ｕｄｐ）、その塩またはその水和物の製造方法 - Google Patents

ウリジン５’－二リン酸（ｕｄｐ）、その塩またはその水和物の製造方法 Download PDF

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Publication number
JP7405991B2
JP7405991B2 JP2022537892A JP2022537892A JP7405991B2 JP 7405991 B2 JP7405991 B2 JP 7405991B2 JP 2022537892 A JP2022537892 A JP 2022537892A JP 2022537892 A JP2022537892 A JP 2022537892A JP 7405991 B2 JP7405991 B2 JP 7405991B2
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Prior art keywords
uridine
udp
chemical formula
represented
salt
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Japanese (ja)
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JP2023511656A (ja
Inventor
リーム，ヒョンジョン
リー，セヨンウク
チョ，ギョンヒ
カン，スンコン
リム，ジョンラエ
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Chong Kun Dang Corp
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Chong Kun Dang Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
JP2022537892A 2019-12-18 2020-12-17 ウリジン５’－二リン酸（ｕｄｐ）、その塩またはその水和物の製造方法 Active JP7405991B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020190169482A KR20210077946A (ko) 2019-12-18 2019-12-18 우리딘 5’-디인산(udp), 이의 염 또는 이의 수화물의 제조방법
KR10-2019-0169482 2019-12-18
PCT/KR2020/018514 WO2021125819A1 (ko) 2019-12-18 2020-12-17 우리딘 5'-디인산(udp), 이의 염 또는 이의 수화물의 제조방법

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JP2023511656A JP2023511656A (ja) 2023-03-22
JP7405991B2 true JP7405991B2 (ja) 2023-12-26

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JP2022537892A Active JP7405991B2 (ja) 2019-12-18 2020-12-17 ウリジン５’－二リン酸（ｕｄｐ）、その塩またはその水和物の製造方法

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JP (1) JP7405991B2 (ko)
KR (1) KR20210077946A (ko)
CN (1) CN114846018A (ko)
WO (1) WO2021125819A1 (ko)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001513568A (ja) 1997-08-29 2001-09-04 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 肺疾患を治療するためのウリジン５’−ジホスフェートとその類似体の使用
WO2014103704A1 (ja) 2012-12-28 2014-07-03 ヤマサ醤油株式会社 Ｐ１，ｐ４－ジ（ウリジン５'－）テトラホスフェートの製造法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ501696A (en) 1997-07-25 2001-08-31 Inspire Pharmaceuticals Inc Method for large-scale production of sodium and ammonium salts of di(uridine 5')-tetraphosphate
TW593331B (en) * 1997-07-25 2004-06-21 Inspire Pharmaceuticals Inc Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof
KR102504764B1 (ko) * 2017-06-21 2023-03-02 주식회사 종근당 디뉴클레오사이드 폴리포스페이트 화합물의 제조방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001513568A (ja) 1997-08-29 2001-09-04 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 肺疾患を治療するためのウリジン５’−ジホスフェートとその類似体の使用
WO2014103704A1 (ja) 2012-12-28 2014-07-03 ヤマサ醤油株式会社 Ｐ１，ｐ４－ジ（ウリジン５'－）テトラホスフェートの製造法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Phosphorus, Sulfur, and Silicon and the Related Elements，2019年，194，335-336
Synthetic Communications，2006年，36， 3393-3399

Also Published As

Publication number Publication date
KR20210077946A (ko) 2021-06-28
JP2023511656A (ja) 2023-03-22
CN114846018A (zh) 2022-08-02
WO2021125819A1 (ko) 2021-06-24

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