JP7361720B2 - がんの治療のためのｋｒａｓ ｇ１２ｃ阻害剤 - Google Patents

がんの治療のためのｋｒａｓ ｇ１２ｃ阻害剤 Download PDF

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JP7361720B2
JP7361720B2 JP2020560375A JP2020560375A JP7361720B2 JP 7361720 B2 JP7361720 B2 JP 7361720B2 JP 2020560375 A JP2020560375 A JP 2020560375A JP 2020560375 A JP2020560375 A JP 2020560375A JP 7361720 B2 JP7361720 B2 JP 7361720B2
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cancer
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usa
alkyl
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JP2021522281A (ja
JP2021522281A5 (enExample
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ミナッチ，アナ・エレナ
ロウ，ジョナサン・ディー
ブルツ，ライアン・ポール
ランマン，ブライアン・アラン
シー，ビクター・ジェイ
バートバーガー，マイケル・ディー
チュウ－モイアー，マーガレット
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アムジエン・インコーポレーテツド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020560375A 2018-05-10 2019-05-09 がんの治療のためのｋｒａｓ ｇ１２ｃ阻害剤 Active JP7361720B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862669723P 2018-05-10 2018-05-10
US62/669,723 2018-05-10
PCT/US2019/031535 WO2019217691A1 (en) 2018-05-10 2019-05-09 Kras g12c inhibitors for the treatment of cancer

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JP2021522281A JP2021522281A (ja) 2021-08-30
JP2021522281A5 JP2021522281A5 (enExample) 2022-05-11
JP7361720B2 true JP7361720B2 (ja) 2023-10-16

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US (1) US10988485B2 (enExample)
EP (1) EP3790886B1 (enExample)
JP (1) JP7361720B2 (enExample)
AU (1) AU2019265822B2 (enExample)
CA (1) CA3099045A1 (enExample)
ES (1) ES2986917T3 (enExample)
MA (1) MA52564A (enExample)
MX (1) MX2020011907A (enExample)
WO (1) WO2019217691A1 (enExample)

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