JP7308034B2 - 最適化二重ヌクレアーゼ融合物および方法 - Google Patents

最適化二重ヌクレアーゼ融合物および方法 Download PDF

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JP7308034B2
JP7308034B2 JP2018569138A JP2018569138A JP7308034B2 JP 7308034 B2 JP7308034 B2 JP 7308034B2 JP 2018569138 A JP2018569138 A JP 2018569138A JP 2018569138 A JP2018569138 A JP 2018569138A JP 7308034 B2 JP7308034 B2 JP 7308034B2
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polypeptide
amino acid
domain
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acid sequence
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JP2019530430A (ja
JP2019530430A5 (https=
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ジェイムズ アーサー ポサダ，
サンジェイ パテル，
ウェイホン ユー，
クリス ガベル，
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リゾルブ セラピューティクス， エルエルシー
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    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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JP2018569138A 2016-07-01 2017-06-30 最適化二重ヌクレアーゼ融合物および方法 Active JP7308034B2 (ja)

Priority Applications (3)

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JP2022122570A JP7817106B2 (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法
JP2026003402A JP2026063077A (ja) 2016-07-01 2026-01-13 最適化二重ヌクレアーゼ融合物および方法

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US201662357756P 2016-07-01 2016-07-01
US62/357,756 2016-07-01
PCT/US2017/040267 WO2018005954A2 (en) 2016-07-01 2017-06-30 Optimized binuclease fusions and methods

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JP2019530430A5 JP2019530430A5 (https=) 2020-08-06
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JP2022122570A Active JP7817106B2 (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A Pending JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法
JP2026003402A Pending JP2026063077A (ja) 2016-07-01 2026-01-13 最適化二重ヌクレアーゼ融合物および方法

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JP2023208402A Pending JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法
JP2026003402A Pending JP2026063077A (ja) 2016-07-01 2026-01-13 最適化二重ヌクレアーゼ融合物および方法

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US (4) US20190241878A1 (https=)
EP (2) EP3478830B1 (https=)
JP (4) JP7308034B2 (https=)
CN (2) CN109790526A (https=)
AU (2) AU2017290389B2 (https=)
CA (1) CA3029627A1 (https=)
DK (1) DK3478830T3 (https=)
HR (1) HRP20240603T1 (https=)
MA (1) MA45554A (https=)
WO (1) WO2018005954A2 (https=)

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MX341084B (es) 2009-11-02 2016-08-05 Univ Washington Composiciones de nucleasas terapéuticas y métodos.
ES2666303T3 (es) 2011-04-29 2018-05-03 University Of Washington Composiciones terapéuticas de nucleasa y métodos
HRP20192080T1 (hr) 2013-10-31 2020-02-07 Resolve Therapeutics, Llc Terapeutske fuzije nukleaza-albumine i postupci
CA3029627A1 (en) 2016-07-01 2018-01-04 Resolve Therapeutics, Llc Optimized binuclease fusions and methods
CA3073537A1 (en) 2017-08-22 2019-02-28 Sanabio, Llc Soluble interferon receptors and uses thereof
WO2020142740A1 (en) * 2019-01-04 2020-07-09 Resolve Therapeutics, Llc Treatment of sjogren's disease with nuclease fusion proteins
IL294114A (en) * 2020-01-11 2022-08-01 Univ Yale Preparations and methods for the treatment, improvement and/or prevention of diseases or disorders caused by or related to dnase1 and/or dnase1l3
EP4161645A4 (en) * 2020-06-08 2023-11-01 Yale University COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING COAGULOPATHY AND/OR SEPSIS IN PATIENTS WITH BACTERIAL AND/OR VIRAL INFECTIONS
CA3185589A1 (en) * 2020-07-15 2022-01-20 Douglas Matthew ANDERSON Targeted rna cleavage with dcasl3-rnase fusion proteins
CN112322607B (zh) * 2020-11-20 2023-03-28 江南大学 一种融合型腈水合酶及其应用
JP2024507220A (ja) 2021-02-19 2024-02-16 セリピオン， インコーポレイテッド パラオキソナーゼ融合ポリペプチドならびに関連する組成物および方法
WO2025147696A1 (en) * 2024-01-05 2025-07-10 Resolve Therapeutics, Llc Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
US12416020B2 (en) 2024-02-20 2025-09-16 Wyvern Pharmaceuticals Inc. Plasmid encoding a TLR3 and Fc fusion protein

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