JP7250677B2 - Ｔ細胞調節多量体ポリペプチド及びその使用方法 - Google Patents

Ｔ細胞調節多量体ポリペプチド及びその使用方法 Download PDF

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JP7250677B2
JP7250677B2 JP2019534200A JP2019534200A JP7250677B2 JP 7250677 B2 JP7250677 B2 JP 7250677B2 JP 2019534200 A JP2019534200 A JP 2019534200A JP 2019534200 A JP2019534200 A JP 2019534200A JP 7250677 B2 JP7250677 B2 JP 7250677B2
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amino acid
polypeptide
acid sequence
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JP2020511949A5 (enExample
JP2020511949A (ja
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ディー． ザイデル，サード，ロナルド
チャパーロ，ロドルフォ
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キュー バイオファーマ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
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    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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JP2019534200A 2016-12-22 2017-12-20 Ｔ細胞調節多量体ポリペプチド及びその使用方法 Active JP7250677B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022200549A JP7295325B2 (ja) 2016-12-22 2022-12-15 ヘテロ二量体、ホモ二量体及び医薬組成物
JP2023094901A JP7403703B2 (ja) 2016-12-22 2023-06-08 多量体ポリペプチド、ホモ二量体及び医薬組成物
JP2023209381A JP7560641B2 (ja) 2016-12-22 2023-12-12 融合ポリペプチド、医薬組成物、核酸、宿主細胞、及び融合ポリペプチドを作成する方法

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Application Number Priority Date Filing Date Title
US201662438272P 2016-12-22 2016-12-22
US62/438,272 2016-12-22
US201762470774P 2017-03-13 2017-03-13
US62/470,774 2017-03-13
US201762555435P 2017-09-07 2017-09-07
US62/555,435 2017-09-07
US201762582132P 2017-11-06 2017-11-06
US62/582,132 2017-11-06
PCT/US2017/067663 WO2018119114A1 (en) 2016-12-22 2017-12-20 T-cell modulatory multimeric polypeptides and methods of use thereof

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JP2022200549A Active JP7295325B2 (ja) 2016-12-22 2022-12-15 ヘテロ二量体、ホモ二量体及び医薬組成物
JP2023094901A Active JP7403703B2 (ja) 2016-12-22 2023-06-08 多量体ポリペプチド、ホモ二量体及び医薬組成物
JP2023209381A Active JP7560641B2 (ja) 2016-12-22 2023-12-12 融合ポリペプチド、医薬組成物、核酸、宿主細胞、及び融合ポリペプチドを作成する方法

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JP2023094901A Active JP7403703B2 (ja) 2016-12-22 2023-06-08 多量体ポリペプチド、ホモ二量体及び医薬組成物
JP2023209381A Active JP7560641B2 (ja) 2016-12-22 2023-12-12 融合ポリペプチド、医薬組成物、核酸、宿主細胞、及び融合ポリペプチドを作成する方法

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US (21) US20190352363A1 (enExample)
EP (2) EP3558339B1 (enExample)
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KR (1) KR102760578B1 (enExample)
CN (6) CN110325205B (enExample)
AU (1) AU2017379900B2 (enExample)
BR (1) BR112019012964A2 (enExample)
CA (1) CA3043630A1 (enExample)
DK (1) DK3558339T5 (enExample)
ES (1) ES2973548T3 (enExample)
IL (4) IL308851B2 (enExample)
MX (2) MX2019007611A (enExample)
MY (1) MY202029A (enExample)
PH (1) PH12019501413A1 (enExample)
PL (1) PL3558339T3 (enExample)
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SI (1) SI3558339T1 (enExample)
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