JP7229923B2 - ヌクレアーゼ切断を評価する方法 - Google Patents

ヌクレアーゼ切断を評価する方法 Download PDF

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JP7229923B2
JP7229923B2 JP2019536933A JP2019536933A JP7229923B2 JP 7229923 B2 JP7229923 B2 JP 7229923B2 JP 2019536933 A JP2019536933 A JP 2019536933A JP 2019536933 A JP2019536933 A JP 2019536933A JP 7229923 B2 JP7229923 B2 JP 7229923B2
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nucleic acid
genomic dna
sequencing
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acid fragment
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ジョージア ジアンヌコス，
クリストファー ウィルソン，
ドーン チューラ，
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エディタス・メディシン、インコーポレイテッド
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
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    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/50—Mutagenesis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search

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JP2019536933A 2017-01-06 2018-01-05 ヌクレアーゼ切断を評価する方法 Active JP7229923B2 (ja)

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US201762443212P 2017-01-06 2017-01-06
US62/443,212 2017-01-06
US201762502434P 2017-05-05 2017-05-05
US62/502,434 2017-05-05
US201762570300P 2017-10-10 2017-10-10
US62/570,300 2017-10-10
PCT/US2018/012652 WO2018129368A2 (en) 2017-01-06 2018-01-05 Methods of assessing nuclease cleavage

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