JP7120549B2 - Ｔｒｅｋ（ｔｗｉｋ関連ｋチャネル）チャネルのアクチベータ - Google Patents

Ｔｒｅｋ（ｔｗｉｋ関連ｋチャネル）チャネルのアクチベータ Download PDF

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JP7120549B2
JP7120549B2 JP2019530506A JP2019530506A JP7120549B2 JP 7120549 B2 JP7120549 B2 JP 7120549B2 JP 2019530506 A JP2019530506 A JP 2019530506A JP 2019530506 A JP2019530506 A JP 2019530506A JP 7120549 B2 JP7120549 B2 JP 7120549B2
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trek
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JP2020506878A5 (https=
JPWO2018110669A5 (https=
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ダブリュ リンジー，クレイグ
エム ウィーティング，ジョシュア
エム マクゴワン，ケヴィン
エス デントン，ジェロッド
健太郎 八代
晴登 倉田
陽子 関岡
貴大 森
雄三 岩城
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Ono Pharmaceutical Co Ltd
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/4164—1,3-Diazoles
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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