JP7034951B2 - 操作されたウイルスベクターは炎症および免疫応答の誘導を低減する - Google Patents
操作されたウイルスベクターは炎症および免疫応答の誘導を低減する Download PDFInfo
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- JP7034951B2 JP7034951B2 JP2018563666A JP2018563666A JP7034951B2 JP 7034951 B2 JP7034951 B2 JP 7034951B2 JP 2018563666 A JP2018563666 A JP 2018563666A JP 2018563666 A JP2018563666 A JP 2018563666A JP 7034951 B2 JP7034951 B2 JP 7034951B2
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14171—Demonstrated in vivo effect
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022031422A JP7394898B2 (ja) | 2016-06-08 | 2022-03-02 | 操作されたウイルスベクターは炎症および免疫応答の誘導を低減する |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662347302P | 2016-06-08 | 2016-06-08 | |
| US62/347,302 | 2016-06-08 | ||
| PCT/US2017/036525 WO2017214378A1 (en) | 2016-06-08 | 2017-06-08 | Engineered viral vector reduces induction of inflammatory and immune responses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022031422A Division JP7394898B2 (ja) | 2016-06-08 | 2022-03-02 | 操作されたウイルスベクターは炎症および免疫応答の誘導を低減する |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019517266A JP2019517266A (ja) | 2019-06-24 |
| JP2019517266A5 JP2019517266A5 (https=) | 2020-07-16 |
| JP7034951B2 true JP7034951B2 (ja) | 2022-03-14 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018563666A Active JP7034951B2 (ja) | 2016-06-08 | 2017-06-08 | 操作されたウイルスベクターは炎症および免疫応答の誘導を低減する |
| JP2022031422A Active JP7394898B2 (ja) | 2016-06-08 | 2022-03-02 | 操作されたウイルスベクターは炎症および免疫応答の誘導を低減する |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022031422A Active JP7394898B2 (ja) | 2016-06-08 | 2022-03-02 | 操作されたウイルスベクターは炎症および免疫応答の誘導を低減する |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11339396B2 (https=) |
| EP (1) | EP3468605A4 (https=) |
| JP (2) | JP7034951B2 (https=) |
| KR (1) | KR20190017872A (https=) |
| CN (2) | CN114807152A (https=) |
| AU (2) | AU2017277647B2 (https=) |
| WO (1) | WO2017214378A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11339396B2 (en) | 2016-06-08 | 2022-05-24 | President And Fellows Of Harvard College | Engineered viral vector reduces induction of inflammatory and immune responses |
| AU2018364542A1 (en) * | 2017-11-08 | 2020-04-16 | President And Fellows Of Harvard College | Compositions and methods for inhibiting viral vector-induced inflammatory responses |
| US10736957B2 (en) * | 2017-12-19 | 2020-08-11 | President And Fellows Of Harvard College | Enhanced immunogenicity of mRNA with co-encoded adjuvant sequences |
| JP2022518504A (ja) * | 2019-01-24 | 2022-03-15 | ジェネレーション バイオ カンパニー | 閉端dna(cedna)ならびに遺伝子療法または核酸療法に関連する免疫応答を低減させる方法における使用 |
| AU2020225632A1 (en) * | 2019-02-22 | 2021-09-02 | Life Technologies Corporation | Suspension system for adeno associated virus production |
| WO2020232211A1 (en) * | 2019-05-15 | 2020-11-19 | President And Fellows Of Harvard College | Compositions and methods for inhibiting nucleic acid vector- induced inflammatory responses |
| AU2021232069A1 (en) * | 2020-03-05 | 2022-11-03 | Flagship Pioneering Innovations Vi, Llc | Host defense suppressing methods and compositions for modulating a genome |
| CN115698332A (zh) * | 2020-06-12 | 2023-02-03 | 新加坡科技研究局 | 在单细胞水平上评估载体转导效率和/或特异性的方法 |
| US20240141383A1 (en) * | 2021-03-04 | 2024-05-02 | Kriya Therapeutics, Inc. | Viral vector constructs incorporating dna for inhibiting toll like receptors and methods of using the same |
| WO2025087987A1 (en) * | 2023-10-23 | 2025-05-01 | Sartorius Stedim Cellca Gmbh | Plasmids for improved aav titers and empty full ratios |
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| AU2017277647B2 (en) | 2023-07-27 |
| CN109451729B (zh) | 2022-03-22 |
| JP2022066336A (ja) | 2022-04-28 |
| JP2019517266A (ja) | 2019-06-24 |
| AU2023251424A1 (en) | 2023-11-09 |
| US20240043849A1 (en) | 2024-02-08 |
| US11339396B2 (en) | 2022-05-24 |
| CN114807152A (zh) | 2022-07-29 |
| KR20190017872A (ko) | 2019-02-20 |
| EP3468605A1 (en) | 2019-04-17 |
| AU2017277647A1 (en) | 2018-12-13 |
| US20190177731A1 (en) | 2019-06-13 |
| WO2017214378A1 (en) | 2017-12-14 |
| CN109451729A (zh) | 2019-03-08 |
| US20190316151A1 (en) | 2019-10-17 |
| EP3468605A4 (en) | 2020-01-08 |
| JP7394898B2 (ja) | 2023-12-08 |
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