JP7028764B2 - プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法 - Google Patents

プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法 Download PDF

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JP7028764B2
JP7028764B2 JP2018511488A JP2018511488A JP7028764B2 JP 7028764 B2 JP7028764 B2 JP 7028764B2 JP 2018511488 A JP2018511488 A JP 2018511488A JP 2018511488 A JP2018511488 A JP 2018511488A JP 7028764 B2 JP7028764 B2 JP 7028764B2
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JP2018530529A (ja
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グレゴリー ヒンクル
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Alnylam Pharmaceuticals Inc
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JP2018511488A 2015-09-02 2016-08-22 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法 Active JP7028764B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021195074A JP2022033857A (ja) 2015-09-02 2021-12-01 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法
JP2023154150A JP2023166601A (ja) 2015-09-02 2023-09-21 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法
JP2025040860A JP2025106281A (ja) 2015-09-02 2025-03-14 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法

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US201562213224P 2015-09-02 2015-09-02
US62/213,224 2015-09-02
PCT/US2016/047946 WO2017040078A1 (en) 2015-09-02 2016-08-22 PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

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JP2018530529A JP2018530529A (ja) 2018-10-18
JP2018530529A5 JP2018530529A5 (https=) 2019-09-26
JP7028764B2 true JP7028764B2 (ja) 2022-03-02

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JP2018511488A Active JP7028764B2 (ja) 2015-09-02 2016-08-22 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法
JP2021195074A Pending JP2022033857A (ja) 2015-09-02 2021-12-01 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法
JP2023154150A Pending JP2023166601A (ja) 2015-09-02 2023-09-21 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法
JP2025040860A Pending JP2025106281A (ja) 2015-09-02 2025-03-14 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法

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JP2023154150A Pending JP2023166601A (ja) 2015-09-02 2023-09-21 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法
JP2025040860A Pending JP2025106281A (ja) 2015-09-02 2025-03-14 プログラム細胞死１リガンド１（ＰＤ－Ｌ１）ｉＲＮＡ組成物およびその使用方法

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US (2) US10889813B2 (https=)
EP (2) EP3344769B1 (https=)
JP (4) JP7028764B2 (https=)
KR (2) KR20250145703A (https=)
CN (2) CN114525280A (https=)
AU (1) AU2016315584B2 (https=)
CA (1) CA2996873A1 (https=)
EA (1) EA201890619A1 (https=)
PE (1) PE20181131A1 (https=)
SA (1) SA518391045B1 (https=)
SG (1) SG10202007937SA (https=)
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RU2612521C2 (ru) 2009-07-06 2017-03-09 Онтории, Инк. Новые пролекарства нуклеиновых кислот и способы их применения
JP5868324B2 (ja) 2010-09-24 2016-02-24 株式会社Wave Life Sciences Japan 不斉補助基
CN103796657B (zh) 2011-07-19 2017-07-11 波涛生命科学有限公司 合成官能化核酸的方法
PL2872485T3 (pl) 2012-07-13 2021-05-31 Wave Life Sciences Ltd. Asymetryczna grupa pomocnicza
KR102213609B1 (ko) 2012-07-13 2021-02-08 웨이브 라이프 사이언시스 리미티드 키랄 제어
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JPWO2015108047A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
BR112016016400A2 (pt) 2014-01-16 2017-10-03 Wave Life Sciences Ltd Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos
US20180214487A1 (en) 2015-07-21 2018-08-02 The Children's Medical Center Corporation Pd-l1 expressing hematopoietic stem cells and uses
CA2996873A1 (en) 2015-09-02 2017-03-09 Alnylam Pharmaceuticals, Inc. Programmed cell death 1 ligand 1 (pd-l1) irna compositions and methods of use thereof
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