JP7014449B2 - 神経障害を処置するための間葉系細胞由来エキソソーム - Google Patents

神経障害を処置するための間葉系細胞由来エキソソーム Download PDF

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JP7014449B2
JP7014449B2 JP2019508178A JP2019508178A JP7014449B2 JP 7014449 B2 JP7014449 B2 JP 7014449B2 JP 2019508178 A JP2019508178 A JP 2019508178A JP 2019508178 A JP2019508178 A JP 2019508178A JP 7014449 B2 JP7014449 B2 JP 7014449B2
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オフェン,ダニエル
ペレツ,ニシム
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ラモット アット テル アビブ ユニバーシティ, リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • A61P25/00Drugs for disorders of the nervous system
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US201662374852P 2016-08-14 2016-08-14
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PCT/IL2017/050899 WO2018033911A1 (en) 2016-08-14 2017-08-14 Mesenchymal cell-derived exosomes to treat neurological disorders

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EP3990625A4 (en) 2019-06-26 2023-07-19 Technion Research & Development Foundation Limited PRODUCTION OF EXTRACELLULAR VESICLES FROM STEM CELLS
JP6830286B1 (ja) 2020-06-26 2021-02-17 デクソンファーマシューティカルズ株式会社 精巣機能改善剤および精巣機能改善方法
US20230210910A1 (en) 2020-07-17 2023-07-06 Dexon Pharmaceuticals Inc. Method for preventing infection of a healthy person or a healthy animal with a virus that uses ace2 as a receptor, binding inhibitor and medical device
EP4212163A4 (en) 2020-09-08 2024-09-18 Dexon Pharmaceuticals Inc. CYTOKINE STORM INHIBITOR, METHOD FOR USING CYTOKINE STORM INHIBITOR, AND METHOD FOR SCREENING CYTOKINE INHIBITOR
JP6974892B1 (ja) 2021-05-27 2021-12-01 デクソンファーマシューティカルズ株式会社 癌悪液質の改善剤および癌悪液質の改善方法
JP7492757B2 (ja) 2022-03-22 2024-05-30 Dexonファーマシューティカルズ株式会社 遺伝子の発現制御剤、アルツハイマー病の予防薬または治療薬および認知症の改善方法
US20250136992A1 (en) 2022-05-15 2025-05-01 Nurexone Biologic Ltd. Anti-pten rna interference oligonucleotides and uses thereof
CN115006427A (zh) * 2022-05-31 2022-09-06 尧舜泽生物医药(南京)有限公司 骨髓间充质干细胞外泌体在治疗帕金森病中的应用
EP4541359A1 (en) 2022-06-20 2025-04-23 Dexon Pharmaceuticals Inc. Ptx3 expression control agent, prophylactic drug or therapeutic drug for vasculitis or hardening of skin associated with rheumatoid arthritis, autoimmune disease, method for improving vasculitis or hardening of skin associated with rheumatoid arthritis, autoimmune disease
WO2023248844A1 (ja) 2022-06-20 2023-12-28 Dexonファーマシューティカルズ株式会社 Hmgb1の発現制御剤;急性肺損傷、急性呼吸窮迫症候群または敗血症の予防薬または治療薬、あるいはそれらの改善方法
CN120078807B (zh) * 2025-02-08 2026-03-31 广东省人民医院 改善卵巢功能的MSC-sEVs药物及其制备方法和应用

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EP3496730A1 (en) 2019-06-19
EP3496730B1 (en) 2022-05-25
AU2017311684A2 (en) 2019-03-28
AU2017311684B2 (en) 2023-05-04
SG11201901272WA (en) 2019-03-28
AU2017311684A1 (en) 2019-03-07
JP2019524824A (ja) 2019-09-05
IL264825A (cg-RX-API-DMAC7.html) 2019-04-30
EP3496730A4 (en) 2020-05-06
CN109843305B (zh) 2023-03-10
US20210361717A1 (en) 2021-11-25
ES2925527T3 (es) 2022-10-18
CN109843305A (zh) 2019-06-04
US20190209621A1 (en) 2019-07-11
WO2018033911A1 (en) 2018-02-22
US11129852B2 (en) 2021-09-28
PL3496730T3 (pl) 2022-09-26
CA3033951A1 (en) 2018-02-22
IL264825B (en) 2022-08-01

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