JP2019524824A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019524824A5 JP2019524824A5 JP2019508178A JP2019508178A JP2019524824A5 JP 2019524824 A5 JP2019524824 A5 JP 2019524824A5 JP 2019508178 A JP2019508178 A JP 2019508178A JP 2019508178 A JP2019508178 A JP 2019508178A JP 2019524824 A5 JP2019524824 A5 JP 2019524824A5
- Authority
- JP
- Japan
- Prior art keywords
- scz
- schizophrenia
- disease
- neurodevelopmental disorder
- negative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662374852P | 2016-08-14 | 2016-08-14 | |
| US62/374,852 | 2016-08-14 | ||
| PCT/IL2017/050899 WO2018033911A1 (en) | 2016-08-14 | 2017-08-14 | Mesenchymal cell-derived exosomes to treat neurological disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019524824A JP2019524824A (ja) | 2019-09-05 |
| JP2019524824A5 true JP2019524824A5 (cg-RX-API-DMAC7.html) | 2021-12-16 |
| JP7014449B2 JP7014449B2 (ja) | 2022-02-01 |
Family
ID=61196484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019508178A Active JP7014449B2 (ja) | 2016-08-14 | 2017-08-14 | 神経障害を処置するための間葉系細胞由来エキソソーム |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11129852B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3496730B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7014449B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN109843305B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017311684B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2925527T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL264825B (cg-RX-API-DMAC7.html) |
| PL (1) | PL3496730T3 (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201901272WA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018033911A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11648260B2 (en) | 2018-03-29 | 2023-05-16 | Technion Research And Development Foundation Limitted | Vesicles comprising a PTEN inhibitor and uses of same |
| CA3112505C (en) * | 2018-09-20 | 2023-06-20 | Citospin, S.L. | Method for obtaining an enriched population of functional mesenchymal stem cells, cells obtained thereof and compositions comprising the same |
| EP3990625A4 (en) | 2019-06-26 | 2023-07-19 | Technion Research & Development Foundation Limited | PRODUCTION OF EXTRACELLULAR VESICLES FROM STEM CELLS |
| JP6830286B1 (ja) | 2020-06-26 | 2021-02-17 | デクソンファーマシューティカルズ株式会社 | 精巣機能改善剤および精巣機能改善方法 |
| US20230210910A1 (en) | 2020-07-17 | 2023-07-06 | Dexon Pharmaceuticals Inc. | Method for preventing infection of a healthy person or a healthy animal with a virus that uses ace2 as a receptor, binding inhibitor and medical device |
| EP4212163A4 (en) | 2020-09-08 | 2024-09-18 | Dexon Pharmaceuticals Inc. | CYTOKINE STORM INHIBITOR, METHOD FOR USING CYTOKINE STORM INHIBITOR, AND METHOD FOR SCREENING CYTOKINE INHIBITOR |
| JP6974892B1 (ja) | 2021-05-27 | 2021-12-01 | デクソンファーマシューティカルズ株式会社 | 癌悪液質の改善剤および癌悪液質の改善方法 |
| JP7492757B2 (ja) | 2022-03-22 | 2024-05-30 | Ｄｅｘｏｎファーマシューティカルズ株式会社 | 遺伝子の発現制御剤、アルツハイマー病の予防薬または治療薬および認知症の改善方法 |
| US20250136992A1 (en) | 2022-05-15 | 2025-05-01 | Nurexone Biologic Ltd. | Anti-pten rna interference oligonucleotides and uses thereof |
| CN115006427A (zh) * | 2022-05-31 | 2022-09-06 | 尧舜泽生物医药(南京)有限公司 | 骨髓间充质干细胞外泌体在治疗帕金森病中的应用 |
| EP4541359A1 (en) | 2022-06-20 | 2025-04-23 | Dexon Pharmaceuticals Inc. | Ptx3 expression control agent, prophylactic drug or therapeutic drug for vasculitis or hardening of skin associated with rheumatoid arthritis, autoimmune disease, method for improving vasculitis or hardening of skin associated with rheumatoid arthritis, autoimmune disease |
| WO2023248844A1 (ja) | 2022-06-20 | 2023-12-28 | Ｄｅｘｏｎファーマシューティカルズ株式会社 | Ｈｍｇｂ１の発現制御剤；急性肺損傷、急性呼吸窮迫症候群または敗血症の予防薬または治療薬、あるいはそれらの改善方法 |
| CN120078807B (zh) * | 2025-02-08 | 2026-03-31 | 广东省人民医院 | 改善卵巢功能的MSC-sEVs药物及其制备方法和应用 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
| US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| US20060188496A1 (en) * | 2005-02-23 | 2006-08-24 | Hanne Bentz | Intranasal administration of active agents to the central nervous system |
| WO2008036374A2 (en) * | 2006-09-21 | 2008-03-27 | Medistem Laboratories, Inc. | Allogeneic stem cell transplants in non-conditioned recipients |
| AU2009203638C1 (en) | 2008-01-04 | 2013-07-25 | Lydac Neuroscience Limited | Microvesicles |
| EP2254586B1 (en) | 2008-02-22 | 2015-04-08 | Agency For Science, Technology And Research (A*star) | Mesenchymal stem cell particles |
| KR20100054711A (ko) * | 2008-11-14 | 2010-05-25 | 메디포스트(주) | 간엽 줄기세포 또는 이의 배양액을 포함하는 신경질환의 예방 또는 치료용 조성물 |
| CN102596177B (zh) * | 2009-07-01 | 2014-05-28 | 阿昂梅迪克斯公司 | 来源于有核哺乳动物细胞的微囊泡及其应用 |
| JPWO2011118795A1 (ja) | 2010-03-26 | 2013-07-04 | 国立大学法人名古屋大学 | 損傷部治療用組成物 |
| JP5608927B2 (ja) * | 2010-04-13 | 2014-10-22 | 国立大学法人名古屋大学 | 歯髄幹細胞を用いた神経疾患治療用組成物 |
| GB201011589D0 (en) | 2010-07-09 | 2010-08-25 | Reneuron Ltd | Therapeutic cells |
| WO2012020308A2 (en) * | 2010-08-13 | 2012-02-16 | The University Court Of The University Of Glasgow | Cellular and molecular therapies |
| WO2012068170A2 (en) * | 2010-11-15 | 2012-05-24 | Jau-Nan Lee | Generation of neural stem cells from human trophoblast stem cells |
| WO2012156968A2 (en) * | 2011-05-19 | 2012-11-22 | Ariel - University Research And Development Company, Ltd. | Use of mesenchymal stem cells for the improvement of affective and cognitive function |
| WO2013124817A2 (en) * | 2012-02-22 | 2013-08-29 | Brainstem Biotec Ltd. | MicroRNAS FOR THE GENERATION OF ASTROCYTES |
| EP2833893B1 (en) | 2012-04-03 | 2018-08-29 | Reneuron Limited | Stem cell microparticles |
| WO2013186735A2 (en) | 2012-06-14 | 2013-12-19 | Bar-Ilan Research And Development Company Ltd. | Photothermal detection |
| WO2015038075A1 (en) * | 2013-09-16 | 2015-03-19 | Agency For Science, Technology And Research | Method |
| WO2016149358A1 (en) | 2015-03-16 | 2016-09-22 | Duncan Ross | Method of treatment comprising membrane-enclosed vesicle |
-
2017
- 2017-08-14 IL IL264825A patent/IL264825B/en unknown
- 2017-08-14 US US16/325,445 patent/US11129852B2/en active Active
- 2017-08-14 PL PL17841210.2T patent/PL3496730T3/pl unknown
- 2017-08-14 WO PCT/IL2017/050899 patent/WO2018033911A1/en not_active Ceased
- 2017-08-14 SG SG11201901272WA patent/SG11201901272WA/en unknown
- 2017-08-14 EP EP17841210.2A patent/EP3496730B1/en active Active
- 2017-08-14 AU AU2017311684A patent/AU2017311684B2/en active Active
- 2017-08-14 ES ES17841210T patent/ES2925527T3/es active Active
- 2017-08-14 JP JP2019508178A patent/JP7014449B2/ja active Active
- 2017-08-14 CN CN201780063347.2A patent/CN109843305B/zh active Active
-
2021
- 2021-08-04 US US17/394,008 patent/US20210361717A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019524824A5 (cg-RX-API-DMAC7.html) | ||
| EP3600434A4 (en) | TREATMENT OF PULMONAL HYPERTENSION | |
| WO2014160871A3 (en) | Methods and agents for treating alzheimer's disease | |
| GT201100283A (es) | Anticuerpos humanizados especificos de la forma protofibrilar del péptido beta-amiloide | |
| AR099307A1 (es) | Sales de triazolo piridina para el tratamiento de trastornos inflamatorios | |
| JP2020528637A5 (cg-RX-API-DMAC7.html) | ||
| UY35311A (es) | Dihidropirimidinonas bicíclicas sustituidas y su uso como inhibidores de la actividad de elastasa neutrofílica | |
| EP3541379A4 (en) | COMPOSITIONS FOR THE TREATMENT OF HYPERTONIA | |
| CU20160155A7 (es) | Compuestos heteroaromáticos útiles como ligandos de dopamina d1 | |
| MX2021007116A (es) | Biomarcadores y usos en el tratamiento de infecciones virales, inflamaciones o cancer. | |
| CL2018001633A1 (es) | Composiciones de benzofenonas polihidroxiladas y métodos para el tratamiento de trastornos neurodegenerativos | |
| ES2526979B1 (es) | Uso del 3-(2-isotiocianatoetil)-5-metoxi-1H-indol para el tratamiento de enfermedades neurodegenerativas | |
| EP3804733A4 (en) | COMPOSITION FOR INFLAMMATORY GASTROINTESTINAL DISEASES | |
| TH152177B (th) | ชิ้นส่วนเสริมตัวถังด้านล่างสำหรับรถยนต์ | |
| CN302581037S (zh) | 汽车前大灯 | |
| TH70167S1 (th) | ไฟหน้าสำหรับรถยนต์ | |
| TH144268S (th) | เชิงเทียน | |
| CN302537556S (zh) | 长排警示灯（tbd631103） | |
| JP2015522004A5 (cg-RX-API-DMAC7.html) | ||
| TH140986S (th) | รถยนต์ | |
| TH61658S1 (th) | เชิงเทียน | |
| TH140913S (th) | รถยนต์ | |
| TH77043B (th) | การใช้โลหะเจืออะลูมินา-โครเมียมในการปรับสภาพด้วยความร้อน | |
| CN302526121S (zh) | 汽车格栅（ⅱ） | |
| CN302432817S (zh) | 汽车前组合灯（乘用皮卡m2p1） |