JP6993228B2 - 抗トランスフェリン受容体／抗ｂａｃｅ１多重特異性抗体および使用方法 - Google Patents

抗トランスフェリン受容体／抗ｂａｃｅ１多重特異性抗体および使用方法 Download PDF

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JP6993228B2
JP6993228B2 JP2017526560A JP2017526560A JP6993228B2 JP 6993228 B2 JP6993228 B2 JP 6993228B2 JP 2017526560 A JP2017526560 A JP 2017526560A JP 2017526560 A JP2017526560 A JP 2017526560A JP 6993228 B2 JP6993228 B2 JP 6993228B2
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antibody
seq
hvr
nos
sequence
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JP2018505652A (ja
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イーチン リウ，
ジャスビンダル アトウォル，
セシリア プイ チー チウ，
ライアン ジェー． ワッツ，
イェン ウー，
エリック クラウランド，
マイケル フェルトハウス，
イン チャン，
ジョイ ユイ ズッケロ，
ジェシカ カウチ，
マーク エス． デニス，
ジェームズ エー． アーンスト，
グレゴリー エー． ラザール，
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Genentech Inc
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Genentech Inc
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2881—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
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JP2017526560A 2014-11-19 2015-11-18 抗トランスフェリン受容体／抗ｂａｃｅ１多重特異性抗体および使用方法 Active JP6993228B2 (ja)

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US201462081965P 2014-11-19 2014-11-19
US62/081,965 2014-11-19
PCT/US2015/061402 WO2016081640A1 (en) 2014-11-19 2015-11-18 Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use

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JP2018505652A5 JP2018505652A5 (https=) 2018-12-27
JP6993228B2 true JP6993228B2 (ja) 2022-03-03

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JP7305543B2 (ja) 2017-01-26 2023-07-10 スロゼン オペレーティング， インコーポレイテッド 組織特異的Ｗｎｔシグナル増強分子およびその使用
US10143187B2 (en) 2017-02-17 2018-12-04 Denali Therapeutics Inc. Transferrin receptor transgenic models
BR112019016989A2 (pt) 2017-02-17 2020-05-26 Denali Therapeutics Inc. Polipeptídeos de ligação ao receptor de transferrina manipulados
US10457717B2 (en) 2017-02-17 2019-10-29 Denali Therapeutics Inc. Engineered polypeptides
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WO2019094608A1 (en) 2017-11-08 2019-05-16 Denali Therapeutics Inc. Anti-bace1 antibodies and methods of use thereof
JP7779653B2 (ja) 2018-02-07 2025-12-03 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 治療用タンパク質送達のための方法および組成物
TWI857959B (zh) 2018-06-26 2024-10-11 日商協和麒麟股份有限公司 與細胞黏著分子3 結合之抗體
CN112424357B (zh) 2018-06-26 2024-12-24 协和麒麟株式会社 与硫酸软骨素蛋白聚糖5结合的抗体
JP2021530223A (ja) 2018-07-09 2021-11-11 スロゼン， インコーポレイテッド 組織特異性Ｗｎｔシグナル増強分子及びその使用
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JP7506607B2 (ja) * 2018-12-28 2024-06-26 協和キリン株式会社 ＴｆＲに結合するバイスペシフィック抗体
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