JP6943850B2 - プランジャ及びシリンジ - Google Patents
プランジャ及びシリンジ Download PDFInfo
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- JP6943850B2 JP6943850B2 JP2018521845A JP2018521845A JP6943850B2 JP 6943850 B2 JP6943850 B2 JP 6943850B2 JP 2018521845 A JP2018521845 A JP 2018521845A JP 2018521845 A JP2018521845 A JP 2018521845A JP 6943850 B2 JP6943850 B2 JP 6943850B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31515—Connection of piston with piston rod
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M2005/14573—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for quick connection/disconnection with a driving system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/332—Force measuring means
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- Health & Medical Sciences (AREA)
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
本出願は、2015年10月28日に出願された「注入器とのシリンジプランジャ係合のためのシステム及び方法」と題される米国特許出願第14/925,722号の優先権を主張し、その開示内容はその全体が本願に組み入れられる。
近位端と、遠位端と、プランジャ縦軸に沿って近位端と遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
プランジャ本体に取り付けられる第1のセグメントと、プランジャ本体の遠位端に向けて突出して第1のセグメントに対して撓むことができる第2のセグメントとを有する少なくとも1つの弾性的に撓み可能な保持部材と、
少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つの作動部材と、
を備え、
少なくとも1つの作動部材は、ピストンに対するプランジャの回転時にプランジャと係合して少なくとも1つの弾性的に撓み可能な保持部材を撓ませるために使用されるピストンと相互作用する、
プランジャ。
近位端と、遠位端と、プランジャ縦軸に沿って近位端と遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
プランジャ本体に取り付けられる第1のセグメントと、プランジャ本体の遠位端に向けて突出して第1のセグメントに対して撓むことができる第2の端部とを有する少なくとも1つの弾性的に撓み可能な保持部材と、
プランジャ本体又は少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つのアライメント部材と、
を備え、
少なくとも1つのアライメント部材は、ピストンを、プランジャとピストンとの係合中にプランジャとの自己配向位置合わせ状態へと案内する、
プランジャ。
近位端と、遠位端と、プランジャ縦軸に沿って近位端と遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
プランジャ本体に取り付けられる第1のセグメントと、第1のセグメントに対して撓むことができる第2のセグメントとを有する少なくとも1つの弾性的に撓み可能な保持部材と、
プランジャ本体又は前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つのアライメント部材と、
少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つの作動部材と、
を備え、
少なくとも1つのアライメント部材は、ピストンを、プランジャとピストンとの係合中にプランジャとの自己配向位置合わせ状態へと案内し、
少なくとも1つの作動部材は、ピストンからのプランジャの離脱中におけるピストンに対するプランジャの回転時にピストンと相互作用して少なくとも1つの弾性的に撓み可能な保持部材を撓ませる、
プランジャ。
バレル内に摺動可能に配置されてバレル近位端とバレル遠位端との間で往復移動できるプランジャと、
を備え、
プランジャは、
近位端と、遠位端と、プランジャ縦軸に沿って近位端と遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
プランジャ本体に取り付けられる第1のセグメントと、プランジャ本体の遠位端に向けて突出して第1のセグメントに対して撓むことができる第2のセグメントとを有する少なくとも1つの弾性的に撓み可能な保持部材と、
少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つの作動部材と、
を備え、
少なくとも1つの作動部材は、ピストンに対するプランジャの回転時にプランジャと係合して少なくとも1つの弾性的に撓み可能な保持部材を径方向に撓ませるために使用されるピストンと相互作用する、
シリンジ。
11 流体検証部材
12 シリンジ
14 ハウジング
15 シリンジ縦軸
16 シリンジポート
17 流体経路セット
18 シリンジバレル
19 シリンジ側壁
20 近位端
21 外面
22 ノズル
23 内面
24 遠位端
25 内容積
26 プランジャ
30 挿入部分
32 プランジャ本体
34 プランジャ縦軸
35 滴下フランジ
36 近位端
38 遠位端
39 周方向側壁
40 内部キャビティ
42 円錐形状部
44 円筒形状部
46 切頂端部
48 中心開口
49 開口
52 内面
56 延在部
58 プランジャカバー
59 シール
60 外面
62 周方向溝
64 外面
66 シール要素
68 保持部材
69 ポケット
70 第1の端部
71 第1のアライメント部材
71a 第1の端部
71b 第2の端部
72 第2の端部
73 開口、第1の端部
74 キャッチ部
74a キャッチ部
75 第2の端部
77a 近位側アライメント面
77b 遠位側アライメント面
78 第1のカム部材
78a 第1のカム部材
79 検知部材
81 弾性要素
83 係合表面
88 ピストン
90 ステム
91 キャビティ
92 ピストンヘッド、プランジャヘッド
93 環状カラー
94 遠位端
95 キャップ
97 バットレス
98 第2のカム部材、作動面
98a 面取り部、カム面
99 一方向回転機構
101 中心シャフト、山部、溝
102 シール
103 近位部、溝
105 遠位部、ギア面
107 面取り縁部
109 径方向リップ
111 ロック張出部
111a ロック張出部
113 第2のアライメント部材
114 第1のアダプタ
115 ピストン縦軸
116 第1の部分
117 案内面
118 接続機構
119 凹部
120 第2の部分
121 底面
122 第2のアダプタ
123 リップ
124 第1の部分
125 接続機構
126 接続機構
128 第2の部分
130 第1の部分
132 第1の端部
134 第2の端部
136 移行部
138 第1の端部
140 第2の部分
142 第2の端部
170 ポケット
171 ストッパ部材
215 取り付け機構
260 プランジャ
320 プランジャ本体
340 プランジャ縦軸
360 近位端
380 遠位端
390 周方向側壁
400 内部キャビティ
420 円錐形状部
440 円筒形状部
460 切頂端部
480 中心開口
520 内面
680 保持部材
700 第1の端部
720 第2の端部
740 キャッチ部
780 第1のカム部材
800 歯
820 ピーク山部
825 第1のアライメント部材
826 近位端又は先端
827 遠位端
828 近位側アライメント面
840 溝
860 ギア面
880 ピストン
900 ピストンステム
920 ピストンヘッド
925 第2のアライメント部材
926 第2の縁部
927 第1の縁部
928 表面
940 遠位端
950 カラー
960 近位端
970 環状空間
980 第2のカム部材
990 歯車
1000 底部側壁
1010 第2のアライメント部材
1020 座部
1040 第1の端部
1060 ばね
1080 第2の端部
1100 捕捉リング
1120 第1の径方向リップ
1500 検知部材
1510 第2の径方向リップ
1520 案内溝
1530 溝付き径方向縁部
Claims (30)
- シリンジと共に使用するためのプランジャであって、
近位端と、遠位端と、プランジャ縦軸に沿って前記近位端と前記遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
前記プランジャ本体に取り付けられる第1のセグメントと、前記プランジャ本体の前記遠位端に向けて突出して前記第1のセグメントに対して撓むことができる第2のセグメントとを有する少なくとも1つの弾性的に撓み可能な保持部材と、
前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つの作動部材と、
を備え、
前記少なくとも1つの作動部材は、ピストンに対する前記プランジャの回転時に前記プランジャと係合して前記少なくとも1つの弾性的に撓み可能な保持部材を撓ませるために使用される前記ピストンと相互作用する、
プランジャ。 - 前記プランジャ本体又は前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つのアライメント部材を更に備え、前記少なくとも1つのアライメント部材は、前記ピストンを前記プランジャと自己配向させるためのアライメント面を有する請求項1に記載のプランジャ。
- 前記少なくとも1つのアライメント部材は、前記プランジャ縦軸周りで離間される複数のアライメント部材を備える請求項2に記載のプランジャ。
- 前記複数のアライメント部材が前記プランジャ縦軸周りで等しい径方向間隔で離間される請求項3に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントは、前記プランジャ縦軸から離れるように前記第1のセグメントに対して径方向に撓むことができる請求項1に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材は、前記第1のセグメントと前記第2のセグメントとの間で直線状に又は曲線状に連続している請求項1に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントは、前記プランジャ縦軸に向けて傾けられる請求項1に記載のプランジャ。
- 前記少なくとも1つの作動部材は、前記少なくとも1つの弾性的に撓み可能な保持部材の表面上に設けられる請求項1に記載のプランジャ。
- 前記少なくとも1つの作動部材は、前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントにある請求項8に記載のプランジャ。
- 前記少なくとも1つの作動部材は、前記少なくとも1つの弾性的に撓み可能な保持部材の本体によって画定される平面に対して傾けられる請求項1に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材は、前記プランジャ縦軸周りで離間される複数の弾性的に撓み可能な保持部材を備える請求項1に記載のプランジャ。
- 前記複数の弾性的に撓み可能な保持部材は、前記プランジャ縦軸周りで等しい径方向間隔で離間される請求項11に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントの末端面が前記ピストンの表面と係合して前記プランジャを前記ピストンと解放可能にロックする請求項1に記載のプランジャ。
- 前記末端面が直線状である請求項13に記載のプランジャ。
- 前記末端面は、前記プランジャ縦軸の方向に対して垂直である又は傾斜している請求項13に記載のプランジャ。
- 前記プランジャ本体は、前記プランジャ本体の前記遠位端にある円錐形状部と前記プランジャ本体の前記近位端にある円筒形状部とを伴う内部キャビティを画定する請求項1に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第1のセグメントが前記プランジャ本体の内面に取り付けられる請求項16に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材は、前記プランジャ本体の前記内面から前記内部キャビティ内へ突出する請求項17に記載のプランジャ。
- 前記プランジャ本体の外面の少なくとも一部を覆うように配置されるプランジャカバーを更に備え、前記プランジャカバーは、前記プランジャカバーの周方向側壁の少なくとも一部の周りに配置される弾性シールを備える請求項1に記載のプランジャ。
- 前記弾性シールは、前記プランジャ本体の前記周方向側壁の溝内に少なくとも部分的に位置付けられる内面と、シリンジのバレルと摺動可能に係合するようになっている外面とを備える請求項19に記載のプランジャ。
- 前記少なくとも1つの作動部材がカム部材である請求項1に記載のプランジャ。
- シリンジと共に使用するためのプランジャであって、
近位端と、遠位端と、プランジャ縦軸に沿って前記近位端と前記遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
前記プランジャ本体に取り付けられる第1のセグメントと、前記プランジャ本体の前記遠位端に向けて突出して前記第1のセグメントに対して撓むことができる第2のセグメントとを有する少なくとも1つの弾性的に撓み可能な保持部材と、
前記プランジャ本体又は前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つのアライメント部材と、
を備え、
前記少なくとも1つのアライメント部材は、ピストンを、前記プランジャと前記ピストンとの係合中に前記プランジャと自己配向させる、
プランジャ。 - 前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つの作動部材を更に備え、前記少なくとも1つの作動部材は、前記ピストンからの前記プランジャの離脱中における前記ピストンに対する前記プランジャの回転時に前記ピストンと相互作用して前記少なくとも1つの弾性的に撓み可能な保持部材を撓ませる請求項22に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントの末端面が前記ピストンの表面と係合して前記プランジャを前記ピストンと解放可能にロックする請求項23に記載のプランジャ。
- 前記少なくとも1つの作動部材は、前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントにある請求項23に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントは、前記プランジャ縦軸から離れるように前記第1のセグメントに対して径方向に撓むことができる請求項23に記載のプランジャ。
- シリンジと共に使用するためのプランジャであって、
近位端と、遠位端と、プランジャ縦軸に沿って前記近位端と前記遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
前記プランジャ本体に取り付けられる第1のセグメントと、前記第1のセグメントに対して撓むことができる第2のセグメントとを有する少なくとも1つの弾性的に撓み可能な保持部材と、
前記プランジャ本体又は前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つのアライメント部材と、
前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つの作動部材と、
を備え、
前記少なくとも1つのアライメント部材は、ピストンを、前記プランジャと前記ピストンとの係合中に前記プランジャと自己配向させ、
前記少なくとも1つの作動部材は、前記ピストンからの前記プランジャの離脱中における前記ピストンに対する前記プランジャの回転時に前記ピストンと相互作用して前記少なくとも1つの弾性的に撓み可能な保持部材を撓ませる、
プランジャ。 - 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントが前記プランジャ本体の前記遠位端に向けて突出し、前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントが前記プランジャ縦軸から離れるように前記第1のセグメントに対して径方向に撓むことができる請求項27に記載のプランジャ。
- 前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントが前記プランジャ本体の前記プランジャ縦軸周りで周方向に突出し、前記少なくとも1つの弾性的に撓み可能な保持部材の前記第2のセグメントが前記第1のセグメントに対して周方向に撓むことができる請求項27に記載のプランジャ。
- バレル近位端と、排出ノズルを有するバレル遠位端と、前記バレル近位端と前記バレル遠位端との間で延びるバレル側壁とを有するバレルと、
前記バレル内に摺動可能に配置されて前記バレル近位端と前記バレル遠位端との間で往復移動できるプランジャと、
を備え、
前記プランジャは、
近位端と、遠位端と、プランジャ縦軸に沿って前記近位端と前記遠位端との間で延びる周方向側壁とを有するプランジャ本体と、
前記プランジャ本体に取り付けられる第1のセグメントと、前記プランジャ本体の前記遠位端に向けて突出して前記第1のセグメントに対して撓むことができる第2のセグメントとを有する少なくとも1つの弾性的に撓み可能な保持部材と、
前記少なくとも1つの弾性的に撓み可能な保持部材と関連付けられる少なくとも1つの作動部材と、
を備え、
前記少なくとも1つの作動部材は、ピストンに対する前記プランジャの回転時に前記プランジャと係合して前記少なくとも1つの弾性的に撓み可能な保持部材を径方向に撓ませるために使用される前記ピストンと相互作用する、
シリンジ。
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