JP6923543B2 - Ｎｒ２ｂ選択的ｎｍｄａ調節因子としての置換１，２，３−トリアゾール - Google Patents

Ｎｒ２ｂ選択的ｎｍｄａ調節因子としての置換１，２，３−トリアゾール Download PDF

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JP6923543B2
JP6923543B2 JP2018541636A JP2018541636A JP6923543B2 JP 6923543 B2 JP6923543 B2 JP 6923543B2 JP 2018541636 A JP2018541636 A JP 2018541636A JP 2018541636 A JP2018541636 A JP 2018541636A JP 6923543 B2 JP6923543 B2 JP 6923543B2
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triazole
methoxy
phenyl
pyrimidine
fluoro
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JP2019504854A (ja
JP2019504854A5 (https=
Inventor
チェン，ガン
シー． クロヴィアン，クリスタ
シー． クロヴィアン，クリスタ
アール． コート，ヘザー
アール． コート，ヘザー
エー． ドゥヴォラク，カート
エー． ドゥヴォラク，カート
エフ． ゲリン，クリスティン
エフ． ゲリン，クリスティン
ヒスコックス，アフトン
エー． リタヴィック，マイケル
エー． リタヴィック，マイケル
シー． レック，ジェィソン
シー． レック，ジェィソン
ソヨデ−ジョンソン，アキノラ
ステン，ブライス
エル． ウォール，ジェシカ
エル． ウォール，ジェシカ
ジャン，ウェイ
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ヤンセン ファーマシューティカ エヌ．ベー．
ヤンセン ファーマシューティカ エヌ．ベー．
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
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  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Biomedical Technology (AREA)
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  • Urology & Nephrology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2018541636A 2016-02-10 2017-02-09 Ｎｒ２ｂ選択的ｎｍｄａ調節因子としての置換１，２，３−トリアゾール Expired - Fee Related JP6923543B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662293680P 2016-02-10 2016-02-10
US62/293,680 2016-02-10
PCT/US2017/017093 WO2017139428A1 (en) 2016-02-10 2017-02-09 Substituted 1,2,3-triazoles as nr2b-selective nmda modulators

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JP2019504854A JP2019504854A (ja) 2019-02-21
JP2019504854A5 JP2019504854A5 (https=) 2020-03-26
JP6923543B2 true JP6923543B2 (ja) 2021-08-18

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US (3) US10071988B2 (https=)
EP (1) EP3414233A1 (https=)
JP (1) JP6923543B2 (https=)
KR (1) KR20180108822A (https=)
CN (1) CN109071488B (https=)
AU (1) AU2017217542B2 (https=)
BR (1) BR112018016329A2 (https=)
CA (1) CA3014314A1 (https=)
EA (1) EA201891799A1 (https=)
IL (1) IL261046B (https=)
MA (1) MA44008A (https=)
MX (1) MX2018009752A (https=)
SG (1) SG11201806750WA (https=)
WO (1) WO2017139428A1 (https=)

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HRP20200410T1 (hr) 2015-07-09 2020-08-21 Janssen Pharmaceutica Nv Supstituirani 4-azaindoli i njihova upotreba kao modulatora glun2b receptora
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KR20180108822A (ko) 2018-10-04
JP2019504854A (ja) 2019-02-21
MA44008A (fr) 2018-12-19
WO2017139428A1 (en) 2017-08-17
EP3414233A1 (en) 2018-12-19
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