JP6921750B2 - ペプチドミニ遺伝子発現系を含むリステリアベースの組成物およびその使用方法 - Google Patents

ペプチドミニ遺伝子発現系を含むリステリアベースの組成物およびその使用方法 Download PDF

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JP6921750B2
JP6921750B2 JP2017545631A JP2017545631A JP6921750B2 JP 6921750 B2 JP6921750 B2 JP 6921750B2 JP 2017545631 A JP2017545631 A JP 2017545631A JP 2017545631 A JP2017545631 A JP 2017545631A JP 6921750 B2 JP6921750 B2 JP 6921750B2
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gene
listeria
protein
acta
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JP2018508212A5 (cg-RX-API-DMAC7.html
JP2018508212A (ja
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ロバート プティ，
ロバート プティ，
マイケル エフ． プリンシオッタ，
マイケル エフ． プリンシオッタ，
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アドバクシス， インコーポレイテッド
アドバクシス， インコーポレイテッド
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N9/90—Isomerases (5.)
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    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
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    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20071—Demonstrated in vivo effect

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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JP2017545631A 2015-03-03 2016-03-03 ペプチドミニ遺伝子発現系を含むリステリアベースの組成物およびその使用方法 Expired - Fee Related JP6921750B2 (ja)

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US201562127614P 2015-03-03 2015-03-03
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PCT/US2016/020571 WO2016141121A1 (en) 2015-03-03 2016-03-03 Listeria-based compositions comprising a peptide minigene expression system and methods of use thereof

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US (3) US10900044B2 (cg-RX-API-DMAC7.html)
EP (1) EP3265553A4 (cg-RX-API-DMAC7.html)
JP (2) JP6921750B2 (cg-RX-API-DMAC7.html)
KR (1) KR20170120119A (cg-RX-API-DMAC7.html)
CN (1) CN107406822A (cg-RX-API-DMAC7.html)
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