JP6869336B2 - シクロスポリンを含む眼科用組成物 - Google Patents

シクロスポリンを含む眼科用組成物 Download PDF

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JP6869336B2
JP6869336B2 JP2019515899A JP2019515899A JP6869336B2 JP 6869336 B2 JP6869336 B2 JP 6869336B2 JP 2019515899 A JP2019515899 A JP 2019515899A JP 2019515899 A JP2019515899 A JP 2019515899A JP 6869336 B2 JP6869336 B2 JP 6869336B2
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cyclosporine
composition
water content
perfluorobutyl
pentane
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JP2019529457A5 (https=
JP2019529457A (ja
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フランク ルッシャー，
フランク ルッシャー，
グリレンベルガー，ラルフ
ヨハン エングブロム，
ヨハン エングブロム，
Original Assignee
ノバリック ゲーエムベーハー
ノバリック ゲーエムベーハー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2019515899A 2016-09-23 2017-09-22 シクロスポリンを含む眼科用組成物 Active JP6869336B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16190431.3 2016-09-23
EP16190431 2016-09-23
PCT/EP2017/074079 WO2018055101A1 (en) 2016-09-23 2017-09-22 Ophthalmic compositions comprising ciclosporin

Publications (3)

Publication Number Publication Date
JP2019529457A JP2019529457A (ja) 2019-10-17
JP2019529457A5 JP2019529457A5 (https=) 2020-11-12
JP6869336B2 true JP6869336B2 (ja) 2021-05-12

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JP2019515899A Active JP6869336B2 (ja) 2016-09-23 2017-09-22 シクロスポリンを含む眼科用組成物

Country Status (10)

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US (3) US10813976B2 (https=)
EP (1) EP3515467B1 (https=)
JP (1) JP6869336B2 (https=)
KR (1) KR20190057338A (https=)
CN (1) CN109906085B (https=)
AU (1) AU2017329983B2 (https=)
CA (1) CA3036306C (https=)
ES (1) ES2965677T3 (https=)
MX (1) MX2019003364A (https=)
WO (1) WO2018055101A1 (https=)

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KR20200059272A (ko) 2017-09-27 2020-05-28 노바리크 게엠베하 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물
CN111182893A (zh) 2017-10-04 2020-05-19 诺瓦利克有限责任公司 包含f6h8的眼用组合物
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KR102882058B1 (ko) 2018-03-28 2025-11-07 노바리크 게엠베하 티몰롤을 포함하는 약제학적 조성물
JP2021522219A (ja) 2018-04-27 2021-08-30 ノバリック ゲーエムベーハー 緑内障の治療のためのタフルプロストを含む眼科用組成物
SG11202102820VA (en) 2018-10-12 2021-04-29 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
CN113710228A (zh) 2019-02-13 2021-11-26 诺瓦利克有限责任公司 用于治疗眼部新生血管形成的组合物和方法
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EP3515467A1 (en) 2019-07-31
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US20210023166A1 (en) 2021-01-28
AU2017329983A1 (en) 2019-04-04
US10813976B2 (en) 2020-10-27
CN109906085B (zh) 2024-03-08
AU2017329983B2 (en) 2022-05-05
WO2018055101A1 (en) 2018-03-29
CA3036306A1 (en) 2018-03-29
US20200023035A1 (en) 2020-01-23
EP3515467B1 (en) 2023-11-29
KR20190057338A (ko) 2019-05-28
CN109906085A (zh) 2019-06-18
JP2019529457A (ja) 2019-10-17
US20220354926A1 (en) 2022-11-10
US11400132B2 (en) 2022-08-02
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