JP6827415B2 - 疾患の処置のための併用療法 - Google Patents

疾患の処置のための併用療法 Download PDF

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JP6827415B2
JP6827415B2 JP2017523286A JP2017523286A JP6827415B2 JP 6827415 B2 JP6827415 B2 JP 6827415B2 JP 2017523286 A JP2017523286 A JP 2017523286A JP 2017523286 A JP2017523286 A JP 2017523286A JP 6827415 B2 JP6827415 B2 JP 6827415B2
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antibody
agent
pathway inhibitor
dll4
notch
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JP2017537892A (ja
JP2017537892A5 (enExample
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クリストファー ラモンド マリエル
クリストファー ラモンド マリエル
ティモシー チャールズ ヘイ
ティモシー チャールズ ヘイ
オースティン エル． ガーニー
オースティン エル． ガーニー
ジュリー ミシェル ローダ
ジュリー ミシェル ローダ
ミヌ ケイ． シュリーヴァスタヴァ
ミヌ ケイ． シュリーヴァスタヴァ
インキョン パク
インキョン パク
ヤコブ デュポン
ヤコブ デュポン
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メレオ バイオファーマ ５ インコーポレイテッド
メレオ バイオファーマ ５ インコーポレイテッド
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A—HUMAN NECESSITIES
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    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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JP2017523286A 2014-10-31 2015-10-30 疾患の処置のための併用療法 Active JP6827415B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201462073634P 2014-10-31 2014-10-31
US62/073,634 2014-10-31
US201562127172P 2015-03-02 2015-03-02
US62/127,172 2015-03-02
US201562192133P 2015-07-14 2015-07-14
US62/192,133 2015-07-14
US201562242567P 2015-10-16 2015-10-16
US62/242,567 2015-10-16
PCT/US2015/058327 WO2016070051A2 (en) 2014-10-31 2015-10-30 Combination therapy for treatment of disease

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JP2017537892A JP2017537892A (ja) 2017-12-21
JP2017537892A5 JP2017537892A5 (enExample) 2018-12-06
JP6827415B2 true JP6827415B2 (ja) 2021-02-10

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US (4) US20160176962A1 (enExample)
EP (1) EP3212233B1 (enExample)
JP (1) JP6827415B2 (enExample)
CN (1) CN107530419B (enExample)
AU (1) AU2015338974B2 (enExample)
CA (1) CA2966042A1 (enExample)
DK (1) DK3212233T3 (enExample)
ES (1) ES2808153T3 (enExample)
MX (1) MX382902B (enExample)
PT (1) PT3212233T (enExample)
WO (1) WO2016070051A2 (enExample)

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