JP6754755B2 - 調節性眼内レンズ用の高分子材料 - Google Patents

調節性眼内レンズ用の高分子材料 Download PDF

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Publication number
JP6754755B2
JP6754755B2 JP2017515953A JP2017515953A JP6754755B2 JP 6754755 B2 JP6754755 B2 JP 6754755B2 JP 2017515953 A JP2017515953 A JP 2017515953A JP 2017515953 A JP2017515953 A JP 2017515953A JP 6754755 B2 JP6754755 B2 JP 6754755B2
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Prior art keywords
fluorosilicone
lens
fumed silica
crosslinked polymer
psi
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Japanese (ja)
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JP2017531471A (ja
JP2017531471A5 (enExample
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シルベストリーニ、トーマス
ヤクーブ、ケビン
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レンスゲン、インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • C08K3/36—Silica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/22—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C08G77/24—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/54—Silicon-containing compounds
    • C08K5/5403—Silicon-containing compounds containing no other elements than carbon or hydrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/04—Polysiloxanes
    • C08L83/08—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/12—Polysiloxanes containing silicon bound to hydrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2383/00—Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon only; Derivatives of such polymers
    • C08J2383/04—Polysiloxanes
    • C08J2383/08—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K2201/00—Specific properties of additives
    • C08K2201/002—Physical properties
    • C08K2201/006—Additives being defined by their surface area

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
JP2017515953A 2014-09-23 2015-09-22 調節性眼内レンズ用の高分子材料 Active JP6754755B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462054303P 2014-09-23 2014-09-23
US62/054,303 2014-09-23
PCT/US2015/051512 WO2016049059A1 (en) 2014-09-23 2015-09-22 Polymeric material for accommodating intraocular lenses

Publications (3)

Publication Number Publication Date
JP2017531471A JP2017531471A (ja) 2017-10-26
JP2017531471A5 JP2017531471A5 (enExample) 2018-10-25
JP6754755B2 true JP6754755B2 (ja) 2020-09-16

Family

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JP2017515953A Active JP6754755B2 (ja) 2014-09-23 2015-09-22 調節性眼内レンズ用の高分子材料

Country Status (5)

Country Link
US (2) US10647831B2 (enExample)
EP (1) EP3197462A4 (enExample)
JP (1) JP6754755B2 (enExample)
CN (1) CN106999507A (enExample)
WO (1) WO2016049059A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011137191A1 (en) 2010-04-27 2011-11-03 Ramgopal Rao Accommodating intraocular lens device
US9220590B2 (en) 2010-06-10 2015-12-29 Z Lens, Llc Accommodative intraocular lens and method of improving accommodation
US9364318B2 (en) 2012-05-10 2016-06-14 Z Lens, Llc Accommodative-disaccommodative intraocular lens
CN109806027A (zh) 2013-11-01 2019-05-28 雷恩斯根公司 双部件调节性人工晶状体设备
WO2015066502A1 (en) 2013-11-01 2015-05-07 Thomas Silvestrini Accomodating intraocular lens device
US10004596B2 (en) 2014-07-31 2018-06-26 Lensgen, Inc. Accommodating intraocular lens device
JP6900376B2 (ja) 2015-12-01 2021-07-07 レンスゲン、インコーポレイテッド 調節式眼内レンズデバイス
EP3463188B1 (en) 2016-05-27 2023-04-26 LensGen, Inc. Lens oil having a narrow molecular weight distribution for intraocular lens devices
CN109890325B (zh) 2016-08-24 2021-10-26 Z晶状体有限责任公司 双模式调节-去调节型人工晶状体
CN113811288B (zh) * 2019-04-05 2024-06-25 弗赛特影像6股份有限公司 氟硅共聚物
JP7302503B2 (ja) * 2020-02-26 2023-07-04 信越化学工業株式会社 吸湿性シリコーン樹脂組成物、有機ｅｌ素子用透明封止材、有機ｅｌ素子用透明乾燥材、およびこれらの使用方法
EP4165134A4 (en) 2020-06-15 2024-07-31 ForSight Vision6, Inc. FLUOROSILICONE POLYMERS, COMPOSITIONS AND THEIR USES
US11357620B1 (en) 2021-09-10 2022-06-14 California LASIK & Eye, Inc. Exchangeable optics and therapeutics
CN115116566B (zh) * 2022-01-18 2023-11-21 中山大学中山眼科中心 一种人工晶状体材料的筛选方法和系统
CN114712026B (zh) * 2022-05-12 2024-11-12 温州医科大学附属眼视光医院 一种构建全混浊型白内障动物模型的方法
CN121127521A (zh) * 2023-05-10 2025-12-12 美国陶氏有机硅公司 氟-硅聚合物的合成

Family Cites Families (307)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032502A (en) * 1975-10-10 1977-06-28 Dow Corning Corporation Organosiloxane compositions for liquid injection
US4373218A (en) 1980-11-17 1983-02-15 Schachar Ronald A Variable power intraocular lens and method of implanting into the posterior chamber
US4512040A (en) 1982-06-09 1985-04-23 Mcclure Hubert L Bifocal intraocular lens
US4720286A (en) 1984-07-20 1988-01-19 Bailey Kelvin E Multifocus intraocular lens
US4585457A (en) 1985-05-16 1986-04-29 Kalb Irvin M Inflatable intraocular lens
US4731078A (en) 1985-08-21 1988-03-15 Kingston Technologies Limited Partnership Intraocular lens
US5059668A (en) * 1986-01-20 1991-10-22 Shin-Etsu Chemical Co., Ltd. Fluorosilicone rubber composition
US5236970A (en) * 1987-02-05 1993-08-17 Allergan, Inc. Optically clear reinforced silicone elastomers of high optical refractive index and improved mechanical properties for use in intraocular lenses
US4842601A (en) 1987-05-18 1989-06-27 Smith S Gregory Accommodating intraocular lens and method of implanting and using same
US5074876A (en) 1987-12-04 1991-12-24 Kelman Charles D Two piece intraocular lens
US4888012A (en) 1988-01-14 1989-12-19 Gerald Horn Intraocular lens assemblies
DE68920167T2 (de) 1988-02-12 1995-06-29 Menicon Co Ltd Verfahren zu Herstellung eines Ballons für eine intraokulare Linse.
US4822360A (en) 1988-03-16 1989-04-18 University Of Utah Inflatable, intraocular lens and method of implanting the lens in the capsule of an eye
US4932966A (en) 1988-08-15 1990-06-12 Storz Instrument Company Accommodating intraocular lens
US4882368A (en) * 1988-09-26 1989-11-21 Dow Corning Corporation Low compression set fluorosilicone rubber
US4892543A (en) 1989-02-02 1990-01-09 Turley Dana F Intraocular lens providing accomodation
US5227447A (en) 1989-12-07 1993-07-13 Shin-Etsu Chemical Co., Ltd. Preparation of high molecular weight organopolysiloxane
US5152788A (en) 1989-12-27 1992-10-06 Minnesota Mining And Manufacturing Company Multifocal diffractive ophthalmic lens and method of manufacture
JPH03202102A (ja) 1989-12-28 1991-09-03 Toray Dow Corning Silicone Co Ltd オルガノポリシロキサン成形物中のシロキサンオリゴマー量の減少方法
US6197059B1 (en) 1990-04-27 2001-03-06 Medevec Licensing, B.V. Accomodating intraocular lens
WO1992017132A1 (de) 1991-03-25 1992-10-15 Albert Daxer Kunstlinse
FR2681524B1 (fr) 1991-09-25 1997-04-04 Mnao Implant cristallinien.
US5171773A (en) * 1991-11-13 1992-12-15 Dow Corning Corporation High strength fluorosilicone rubber
US5275623A (en) 1991-11-18 1994-01-04 Faezeh Sarfarazi Elliptical accommodative intraocular lens for small incision surgery
US5278258A (en) * 1992-05-18 1994-01-11 Allergan, Inc. Cross-linked silicone polymers, fast curing silicone precursor compositions, and injectable intraocular lenses
US5264522A (en) * 1992-09-10 1993-11-23 Shin-Etsu Chemical Co., Ltd. Heat-curable fluorosilicone rubber composition and cured product thereof
US5312860A (en) 1992-09-10 1994-05-17 Shin-Etsu Chemical Co., Ltd. Heat-curable silicone rubber composition and cured product thereof
US5443506A (en) 1992-11-18 1995-08-22 Garabet; Antoine L. Lens with variable optical properties
US5336487A (en) 1993-03-05 1994-08-09 Refojo Miguel F Method of treating eye disorders with silicon/fluorosilicone copolymer oil
US5447987A (en) * 1993-12-24 1995-09-05 Shin-Etsu Chemical Co., Ltd. Organopolysiloxane compositions
DE69511067T2 (de) 1994-01-31 1999-12-09 Bausch & Lomb Inc., Rochester Verfahren zur behandlung von kontaktlinsen mit superkritischen fluidum
US5489302A (en) 1994-05-24 1996-02-06 Skottun; Bernt C. Accommodating intraocular lens
US5583178A (en) * 1994-06-30 1996-12-10 Minnesota Mining And Manufacturing Company Cure-indicating molding and coating composition
US5607472A (en) 1995-05-09 1997-03-04 Emory University Intraocular lens for restoring accommodation and allows adjustment of optical power
US5774274A (en) 1995-05-12 1998-06-30 Schachar; Ronald A. Variable focus lens by small changes of the equatorial lens diameter
JPH09150002A (ja) 1995-11-29 1997-06-10 Shin Etsu Chem Co Ltd シリコーンオイルの精製方法
US5665794A (en) * 1996-05-20 1997-09-09 Dow Corning Corporation Method for controlling cure initiation and curing times of platinum group metal curing fluorosilicone compositions
US5902523A (en) * 1996-06-26 1999-05-11 Allergan IOLs and production methods for same
DE19654488A1 (de) 1996-12-27 1998-07-02 Sueddeutsche Kalkstickstoff Verfahren zur Fraktionierung viscoser Silicone
JPH10316860A (ja) * 1997-03-19 1998-12-02 Dow Corning Asia Ltd 光学用シリカ含有ポリシロキサン樹脂
US5854310A (en) * 1997-07-21 1998-12-29 Dow Corning Corporation Curable fluorosilicone composition having improved lubricity
US6361561B1 (en) 1998-10-13 2002-03-26 Pharmacia & Upjohn Ab Injectable intraocular lens
US6197057B1 (en) 1998-10-27 2001-03-06 Gholam A. Peyman Lens conversion system for teledioptic or difractive configurations
US6117171A (en) 1998-12-23 2000-09-12 Skottun; Bernt Christian Encapsulated accommodating intraocular lens
US7662179B2 (en) 1999-04-09 2010-02-16 Sarfarazi Faezeh M Haptics for accommodative intraocular lens system
US20030060881A1 (en) 1999-04-30 2003-03-27 Advanced Medical Optics, Inc. Intraocular lens combinations
US20060238702A1 (en) 1999-04-30 2006-10-26 Advanced Medical Optics, Inc. Ophthalmic lens combinations
US6767363B1 (en) 1999-11-05 2004-07-27 Bausch & Lomb Surgical, Inc. Accommodating positive and negative intraocular lens system
US6551354B1 (en) 2000-03-09 2003-04-22 Advanced Medical Optics, Inc. Accommodating intraocular lens
SE0001352D0 (sv) * 2000-04-12 2000-04-12 Pharmacia & Upjohn Bv Injectable intraocular accommodating lens
US6613343B2 (en) * 2000-04-12 2003-09-02 Pharmacia Groningen Bv Injectable intraocular accommodating lens
US20050251254A1 (en) 2000-06-02 2005-11-10 Brady Daniel G Method of implanting accommodating intraocular lenses
US6730123B1 (en) 2000-06-22 2004-05-04 Proteus Vision, Llc Adjustable intraocular lens
WO2002005015A2 (en) 2000-07-11 2002-01-17 The Johns Hopkins University School Of Medicine Device for inserting an injectable bag intraocular lens within a human eye
US8062361B2 (en) 2001-01-25 2011-11-22 Visiogen, Inc. Accommodating intraocular lens system with aberration-enhanced performance
US20030078657A1 (en) 2001-01-25 2003-04-24 Gholam-Reza Zadno-Azizi Materials for use in accommodating intraocular lens system
US7087080B2 (en) 2001-01-25 2006-08-08 Visiogen, Inc. Materials for use in intraocular lens system
US7780729B2 (en) 2004-04-16 2010-08-24 Visiogen, Inc. Intraocular lens
US20040148023A1 (en) 2001-02-15 2004-07-29 Shu Stephen K. High gain wide range accommodating intraocular lens for implant into the capsular bag
US20020120329A1 (en) 2001-02-28 2002-08-29 Allergan Sales, Inc. Moveable intraocular lenses and combinations of intraocular lenses
US20030105522A1 (en) 2001-06-11 2003-06-05 Glazier Alan N. Multi-focal intraocular lens
US7229475B2 (en) 2001-06-11 2007-06-12 Vision Solutions Technologies, Inc. Multi-focal intraocular lens, and methods for making and using same
US6855164B2 (en) 2001-06-11 2005-02-15 Vision Solutions Technologies, Llc Multi-focal intraocular lens, and methods for making and using same
IL145015A0 (en) 2001-08-21 2002-06-30 Nun Yehoshua Ben Accommodating lens
US20030060878A1 (en) 2001-08-31 2003-03-27 Shadduck John H. Intraocular lens system and method for power adjustment
US7097660B2 (en) 2001-12-10 2006-08-29 Valdemar Portney Accommodating intraocular lens
JP3985133B2 (ja) * 2001-12-21 2007-10-03 信越化学工業株式会社 チキソ性含フッ素硬化性組成物及びこれを用いた封止物
US20070100445A1 (en) 2003-02-03 2007-05-03 Shadduck John H Intraocular lenses and business methods
US20050021139A1 (en) 2003-02-03 2005-01-27 Shadduck John H. Ophthalmic devices, methods of use and methods of fabrication
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US7261737B2 (en) 2002-12-12 2007-08-28 Powervision, Inc. Accommodating intraocular lens system and method
US6860601B2 (en) 2002-02-06 2005-03-01 John H. Shadduck Adaptive optic lens system and method of use
US20030181749A1 (en) 2002-03-21 2003-09-25 Kunzler Jay F. Supercritical fluid extraction of vitreoretinal silicone tamponades
US6695881B2 (en) 2002-04-29 2004-02-24 Alcon, Inc. Accommodative intraocular lens
WO2004010904A1 (en) 2002-07-29 2004-02-05 Yosef Gross Tensioning intraocular lens assembly
AU2002950469A0 (en) * 2002-07-30 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Improved biomedical compositions
US6966649B2 (en) 2002-08-12 2005-11-22 John H Shadduck Adaptive optic lens system and method of use
FR2844703B1 (fr) 2002-09-25 2005-07-08 Alain Nicolas Gilg Dispositif intraoculaire pour restaurer l'accommodation de l'oeil atteint de presbytie
US20040082993A1 (en) 2002-10-25 2004-04-29 Randall Woods Capsular intraocular lens implant having a refractive liquid therein
US7125422B2 (en) 2002-10-25 2006-10-24 Quest Vision Technology, Inc. Accommodating intraocular lens implant
EP1563337A4 (en) 2002-11-20 2006-05-24 Powervision LENS SYSTEM AND METHOD FOR POWER ADJUSTMENT
US20040111152A1 (en) 2002-12-10 2004-06-10 Kelman Charles David Accommodating multifocal intraocular lens
US7217288B2 (en) 2002-12-12 2007-05-15 Powervision, Inc. Accommodating intraocular lens having peripherally actuated deflectable surface and method
US7247168B2 (en) 2002-12-12 2007-07-24 Powervision, Inc. Accommodating intraocular lens system and method
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US7438723B2 (en) 2002-12-12 2008-10-21 Powervision, Inc. Lens system and method for power adjustment using externally actuated micropumps
US7637947B2 (en) 2002-12-12 2009-12-29 Powervision, Inc. Accommodating intraocular lens system having spherical aberration compensation and method
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
WO2004054471A2 (en) 2002-12-12 2004-07-01 Powervision Accommodating intraocular lens system and method
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US6616691B1 (en) 2003-01-10 2003-09-09 Alcon, Inc. Accommodative intraocular lens
US7238201B2 (en) 2003-02-13 2007-07-03 Visiogen, Inc. Accommodating intraocular lens system with enhanced range of motion
AU2004219674A1 (en) 2003-03-06 2004-09-23 Powervision, Inc. Adaptive optic lens and method of making
US7223288B2 (en) 2003-05-21 2007-05-29 Alcon, Inc. Accommodative intraocular lens
US20040249455A1 (en) 2003-06-09 2004-12-09 Tran Son Trung Accommodative intraocular lens system
GB0319408D0 (en) 2003-08-19 2003-09-17 Chawdhary Satish Intraocular device
DE20316792U1 (de) 2003-08-26 2005-01-05 Schedler, Markus Ciliarmuskel-betätigtes, akkommodationsfähiges Linsenimplantat
DE10346024B4 (de) 2003-08-26 2019-01-17 Carl Zeiss Meditec Ag Ciliarmuskel-betätigtes, akkommodationsfähiges Linsenimplantat
US20050107873A1 (en) 2003-11-18 2005-05-19 Medennium, Inc. Accommodative intraocular lens and method of implantation
US20050137703A1 (en) 2003-12-05 2005-06-23 Vanderbilt University Accommodative intraocular lens
US20050131535A1 (en) 2003-12-15 2005-06-16 Randall Woods Intraocular lens implant having posterior bendable optic
NL1025622C2 (nl) 2004-03-03 2005-09-07 Accolens Internat B V Twee tezamen een lens vormende optische elementen met variabele optische sterkte voor gebruik als intra-oculaire lens.
US7150760B2 (en) 2004-03-22 2006-12-19 Alcon, Inc. Accommodative intraocular lens system
US20110118834A1 (en) 2004-03-31 2011-05-19 Yuhwa Lo Fluidic intraocular lens systems and methods
US7453646B2 (en) 2004-03-31 2008-11-18 The Regents Of The University Of California Fluidic adaptive lens systems and methods
US8018658B2 (en) 2004-03-31 2011-09-13 The Regents Of The Univeristy Of California Fluidic adaptive lens systems and methods
CN101069106A (zh) 2004-03-31 2007-11-07 加利福尼亚大学校务委员会 流体自适应透镜
IL161706A0 (en) 2004-04-29 2004-09-27 Nulens Ltd Intraocular lens fixation device
US9713527B2 (en) 2004-04-30 2017-07-25 Rxsight, Inc. Multilens intraocular lens system with injectable accommodation material
US9005282B2 (en) 2004-04-30 2015-04-14 Calhoun Vision, Inc. Intraocular lens system with injectable accommodation material
US7063723B2 (en) 2004-07-23 2006-06-20 Sun Ran Intraocular lens with an accommodating capability
US20100057095A1 (en) 2004-08-18 2010-03-04 Leonid Orbachevsky Method of Refraction Surgery of the Eye and a Tool for Implanting Intraocular Refractive Lens
US7806929B2 (en) 2004-08-27 2010-10-05 Brown David C Intracapsular pseudophakic device
US20060069178A1 (en) 2004-09-24 2006-03-30 Bausch & Lomb Incorporated Method for polymerizing ophthalmic devices
WO2006040759A1 (en) 2004-10-13 2006-04-20 Nulens Ltd Accommodating intraocular lens (aiol), and aiol assemblies including same
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
SE0403093D0 (sv) 2004-12-20 2004-12-20 Amo Groningen Bv New polysiloxanes; synthesis and use thereof
SE0403091D0 (sv) 2004-12-20 2004-12-20 Amo Groningen Bv New composition for injectable ophtalmic lenses
US20120071972A1 (en) 2004-12-29 2012-03-22 Iris Ginron Zhao Multiphase eyecare
US8216306B2 (en) 2005-01-13 2012-07-10 Minas Theodore Coroneo Ocular auto-focusing lenses
NL1029041C1 (nl) 2005-03-09 2006-09-12 Akkolens Int Bv Verbeterde constructie van een intra-oculaire kunstlens.
EP1890650A2 (en) 2005-03-30 2008-02-27 Nulens Ltd Accommodating intraocular lens (aiol) assemblies, and discrete components therfor
US20060241752A1 (en) 2005-04-20 2006-10-26 Israel Henry M Accommodating multiple lens assembly
WO2007027091A2 (en) 2005-05-13 2007-03-08 Akkolens International B.V. Intra-ocular artificial lens for iris-driven accommodation
EP1726272B1 (de) 2005-05-27 2009-07-08 Wavelight Laser Technologie AG Intraokularlinse
GB2427484A (en) 2005-06-21 2006-12-27 Global Bionic Optics Pty Ltd Variable power fluid lens with flexible wall
US7591849B2 (en) 2005-07-01 2009-09-22 Bausch & Lomb Incorpoted Multi-component accommodative intraocular lens with compressible haptic
US20070016293A1 (en) 2005-07-18 2007-01-18 Alcon, Inc. Accommodative intraocular lens system
US8038711B2 (en) 2005-07-19 2011-10-18 Clarke Gerald P Accommodating intraocular lens and methods of use
US20070032868A1 (en) 2005-08-08 2007-02-08 Randall Woods Capsular shape-restoring device
US7316713B2 (en) 2005-08-29 2008-01-08 Alcon, Inc. Accommodative intraocular lens system
US8034107B2 (en) 2005-09-01 2011-10-11 Stenger Donald C Accommodating intraocular lens
US9629712B2 (en) 2005-09-01 2017-04-25 Donald C. Stenger Accommodating intraocular lens
JP4927371B2 (ja) 2005-09-28 2012-05-09 興和株式会社 眼内レンズ
US9636213B2 (en) 2005-09-30 2017-05-02 Abbott Medical Optics Inc. Deformable intraocular lenses and lens systems
US20070088433A1 (en) 2005-10-17 2007-04-19 Powervision Accommodating intraocular lens system utilizing direct force transfer from zonules and method of use
US8603164B2 (en) 2005-10-27 2013-12-10 Gholam A. Peyman Adjustable fluidic telescope
US20070118216A1 (en) 2005-11-21 2007-05-24 Joel Pynson Accommodative intraocular lens
US7985253B2 (en) 2005-12-07 2011-07-26 C&C Vision International Limited Hydrolic accommodating intraocular lens
US7981155B2 (en) 2005-12-07 2011-07-19 C&C Vision International Limited Hydrolic accommodating intraocular lens
US20070129800A1 (en) 2005-12-07 2007-06-07 C&C Vision International Limited Hydrolic accommodating intraocular lens
EP1969397B1 (en) 2005-12-14 2017-11-08 Novartis AG Method for preparing silicone hydrogels
US20070260308A1 (en) 2006-05-02 2007-11-08 Alcon, Inc. Accommodative intraocular lens system
WO2007134019A2 (en) 2006-05-08 2007-11-22 Bausch & Lomb Incorporated Accommodative intraocular lens having defined axial compression characteristics
US20100004742A1 (en) 2006-08-15 2010-01-07 C7C Vision International Limited Multiocular Intraocular Lens System
US20080046077A1 (en) 2006-08-15 2008-02-21 C&C Vision International Limited Multiocular Intraocular Lens Systems
US20080051886A1 (en) 2006-08-24 2008-02-28 Lin J T Method and device for vision correction via dual-optics accommodating intraocular lens
GB0618262D0 (en) 2006-09-16 2006-10-25 Khoury Elie Accommodative intra-ocular lens
EP1932492B1 (en) 2006-12-13 2011-09-14 Akkolens International B.V. Accommodating intraocular lens with variable correction
WO2008079671A1 (en) 2006-12-22 2008-07-03 Bausch & Lomb Incorporated Multi-element accommodative intraocular lens
AU2007338100B2 (en) 2006-12-22 2014-01-30 Amo Groningen Bv Accommodating intraocular lens, lens system and frame therefor
JP5207626B2 (ja) * 2006-12-26 2013-06-12 東レ・ダウコーニング株式会社 シリコーンゴム層と異種ゴム層からなるゴム積層体用加熱硬化性シリコーンゴム組成物、ゴム積層体およびその製造方法
US7713299B2 (en) 2006-12-29 2010-05-11 Abbott Medical Optics Inc. Haptic for accommodating intraocular lens
CA2674018C (en) 2006-12-29 2015-05-26 Advanced Medical Optics, Inc. Multifocal accommodating intraocular lens
US8608799B2 (en) 2007-01-24 2013-12-17 Tekia, Inc. Umbrella-shaped accommodating artificial ocular lens (AAOL) device
WO2008097915A1 (en) 2007-02-02 2008-08-14 Key Medical Technologies, Inc. Interfacial refraction accommodating lens (iral)
US8034106B2 (en) 2007-02-02 2011-10-11 Adoptics Ag Interfacial refraction accommodating lens (IRAL)
CN101678149B (zh) 2007-02-21 2013-07-17 力景公司 适用于眼用装置的聚合材料及其制造方法
US20080306587A1 (en) 2007-02-21 2008-12-11 Jingjong Your Lens Material and Methods of Curing with UV Light
US7986465B1 (en) 2007-03-01 2011-07-26 Rhevision Technology, Inc. Systems and methods for effecting zoom and focus using fluidic adaptive lenses
WO2008107882A2 (en) 2007-03-05 2008-09-12 Nulens Ltd Unitary accommodating intraocular lenses (aiols) and discrete base members for use therewith
US7753953B1 (en) 2007-03-30 2010-07-13 Kingman Yee Accommodating intraocular lens system
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
WO2009015161A2 (en) 2007-07-23 2009-01-29 Powervision, Inc. Lens material with uv initiator and uv absorber and methods of curing with uv light
JP5346022B2 (ja) 2007-07-23 2013-11-20 パワーヴィジョン・インコーポレーテッド 調節眼内レンズおよび使用方法
EP2178462B1 (en) 2007-07-23 2014-04-02 PowerVision, Inc. Post-implant lens power modification
CN101754728B (zh) 2007-07-23 2013-09-18 力景公司 晶状体递送系统
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
CA2852714C (en) 2007-08-13 2016-10-04 Garth T. Webb Inflatable intra ocular lens/lens retainer
US8377124B2 (en) 2007-10-02 2013-02-19 Novartis Ag Two-element system to provide an ease of accommodation with variable-spherical aberration control
WO2009051477A2 (en) 2007-10-15 2009-04-23 Akkolens International B.V. Adjustable accommodating intraocular lens and positioning means
CA2701510C (en) 2007-11-14 2016-05-10 Alcon Inc. Accommodative intraocular lens system
US9156949B2 (en) 2007-12-21 2015-10-13 Abbott Medical Optics Inc. Silicone containing polymeric materials
US8414646B2 (en) 2007-12-27 2013-04-09 Forsight Labs, Llc Intraocular, accommodating lens and methods of use
US8167941B2 (en) 2008-01-03 2012-05-01 Forsight Labs, Llc Intraocular, accommodating lens and methods of use
US20090198326A1 (en) 2008-01-31 2009-08-06 Medennium Inc. Accommodative intraocular lens system
US7998198B2 (en) 2008-02-07 2011-08-16 Novartis Ag Accommodative IOL with dynamic spherical aberration
US8254034B1 (en) 2008-03-31 2012-08-28 Rhevision Technology, Inc. Fluidic adaptive lens with a lens membrane having suppressed fluid permeability
EP2315559B1 (en) 2008-07-24 2012-01-25 Nulens Ltd Accommodating intraocular lens (aiol) capsules
US20100094412A1 (en) 2008-10-15 2010-04-15 Doug Wensrich Accommodating intraocular lens
US20120232649A1 (en) 2008-11-20 2012-09-13 Insight Innovations, Llc Intraocular Lens Cell Migration Inhibition System
EP2384167A4 (en) 2009-01-09 2016-02-17 Powervision Inc INTRAOCULAR LENSES AND METHODS FOR ASSIGNING THE CAPSULE VARIABILITY AND EYE CHANGES AFTER IMPLANTING
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
WO2010093548A1 (en) * 2009-02-10 2010-08-19 Alcon, Inc. Accommodative intraocular lens system
US8222360B2 (en) 2009-02-13 2012-07-17 Visiogen, Inc. Copolymers for intraocular lens systems
US8657878B2 (en) 2009-02-18 2014-02-25 Hoya Corporation Interfacial refraction accommodating lens (IRAL)
US20100211169A1 (en) 2009-02-19 2010-08-19 Daniel Walter Stanley Intraocular lens configured to offset optical effects caused by optic deformation
WO2010126591A1 (en) 2009-04-29 2010-11-04 Gobi Ramakrishnan Padmanabhan Configurations and methods to manufacture solar cell device with larger capture cross section and higher optical utilization efficiency
US8320049B2 (en) 2009-07-15 2012-11-27 The Penn State Research Foundation Tunable liquid gradient refractive index lens device
US20110029074A1 (en) 2009-08-03 2011-02-03 Abbott Medical Optics Inc. Fixation of ophthalmic implants
EP2473138A4 (en) 2009-08-31 2017-08-16 PowerVision, Inc. Lens capsule size estimation
US20110071628A1 (en) 2009-09-24 2011-03-24 Rainbow Medical Ltd. Accommodative intraocular lens
DE112010004191B4 (de) 2009-10-30 2024-10-10 Akkolens International B.V. Intraokulare Linsen für einen variablen Brennpunkt
US8647384B2 (en) 2009-11-17 2014-02-11 Kenneth L. Lu Accommodating intraocular lens
US9114005B2 (en) 2009-11-17 2015-08-25 Akkolens International B.V. Accommodative intraocular lens driven by ciliary mass
US8357196B2 (en) 2009-11-18 2013-01-22 Abbott Medical Optics Inc. Mark for intraocular lenses
EP2506803A1 (en) 2009-12-04 2012-10-10 AcuFocus, Inc. Corneal implant for refractive correction
GB2476480B (en) 2009-12-22 2013-04-03 Marwan Ghabra Intraocular implant with a fixed and a pivoting lens
WO2011094139A1 (en) 2010-01-26 2011-08-04 Klein, David Accommodating intraocular lens
WO2011106435A2 (en) 2010-02-23 2011-09-01 Powervision, Inc. Fluid for accommodating intraocular lenses
US9034035B2 (en) 2010-03-16 2015-05-19 Mor Research Applications Ltd. Accommodating intraocular lens assembly
WO2011137191A1 (en) 2010-04-27 2011-11-03 Ramgopal Rao Accommodating intraocular lens device
US10736732B2 (en) 2010-06-21 2020-08-11 James Stuart Cumming Intraocular lens with longitudinally rigid plate haptic
WO2012006186A2 (en) 2010-06-29 2012-01-12 The Arizona Board Of Regents On Behalf Of The University Of Arizona Accommodating intraocular lens with deformable material
WO2012006616A2 (en) 2010-07-09 2012-01-12 Powervision, Inc. Intraocular lens delivery devices and methods of use
WO2012023133A1 (en) 2010-08-15 2012-02-23 Nulens Ltd Discrete pre-assembled monolithic aiol assemblages and aiol assemblies including same
ES2935571T3 (es) 2011-02-03 2023-03-08 Akkolens Int B V Combinaciones hápticas para lentes intraoculares acomodativas
EP3685801B1 (en) 2011-02-04 2025-01-22 ForSight Vision6, Inc. Intraocular accommodating lens
US8867141B2 (en) 2011-03-18 2014-10-21 Johnson & Johnson Vision Care, Inc. Lens with multi-concave meniscus wall
JP6071995B2 (ja) 2011-03-24 2017-02-01 パワーヴィジョン・インコーポレーテッド 眼内レンズ装填システムおよび使用方法
WO2012158773A2 (en) 2011-05-16 2012-11-22 Ico, Inc. Filling and implanting accommodative intraocular lenses
US20140227437A1 (en) * 2011-05-23 2014-08-14 California Institute Of Technology Accommodating intraocular lens
US8771347B2 (en) 2011-05-23 2014-07-08 California Institute Of Technology Accommodating intraocular lens
US8715345B2 (en) 2011-05-23 2014-05-06 California Institute Of Technology Accommodating intraocular lens
US9186243B2 (en) 2011-05-31 2015-11-17 Novartis Ag Accommodative intraocular lens and method of implantation
US8257827B1 (en) * 2011-06-02 2012-09-04 The Regents Of The University Of California Silicone composition and devices incorporating same
US8608800B2 (en) 2011-08-02 2013-12-17 Valdemar Portney Switchable diffractive accommodating lens
WO2013016804A1 (en) 2011-08-03 2013-02-07 Webb Garth T Negatively pressurized deformable lens
KR101866873B1 (ko) 2011-08-09 2018-06-14 삼성전자주식회사 곡률 조절 소자 및 방법
JP5594262B2 (ja) 2011-08-29 2014-09-24 信越化学工業株式会社 液状付加硬化型フロロシリコーンゴム組成物及びその成形品
US20130110234A1 (en) 2011-10-28 2013-05-02 Lauren DeVita Dual optic accommodating iol with low refractive index gap material
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
PL2775961T3 (pl) 2011-11-08 2019-06-28 Powervision, Inc. Akomodujące soczewki wewnątrzgałkowe
US9364319B2 (en) 2012-09-25 2016-06-14 Valdemar Portney Refractive-diffractive switchable optical element
JP6270739B2 (ja) 2012-01-24 2018-01-31 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド, ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate モジュール式眼内レンズの設計および方法
US9364316B1 (en) 2012-01-24 2016-06-14 Clarvista Medical, Inc. Modular intraocular lens designs, tools and methods
US10028824B2 (en) 2012-01-24 2018-07-24 Clarvista Medical, Inc. Modular intraocular lens designs, tools and methods
US10080648B2 (en) 2012-01-24 2018-09-25 Clarvista Medical, Inc. Modular intraocular lens designs, tools and methods
US8500806B1 (en) 2012-01-31 2013-08-06 Andrew F. Phillips Accommodating intraocular lens
US8900300B1 (en) 2012-02-22 2014-12-02 Omega Ophthalmics Llc Prosthetic capsular bag and method of inserting the same
EP4338710A3 (en) 2012-03-21 2024-05-22 Alcon Inc. Intraocular lens delivery systems and methods of use
WO2013166068A1 (en) 2012-04-30 2013-11-07 Lensgen, Inc. Method and system for adjusting the refractive power of an implanted intraocular lens
US9084674B2 (en) 2012-05-02 2015-07-21 Abbott Medical Optics Inc. Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity
US9427312B2 (en) 2012-05-25 2016-08-30 California Institute Of Technology Accommodating intraocular composite lens and related methods
JP5872964B2 (ja) * 2012-05-29 2016-03-01 東レ・ダウコーニング株式会社 導電性室温硬化型フルオロシリコーンゴム組成物
FR2992215B1 (fr) 2012-06-21 2014-10-31 Oreal Composition cosmetique anhydre comprenant une huile, des particules d'aerogel de silice hydrophobe, un actif hydrophile et au moins un agent tensioactif
JP5803845B2 (ja) * 2012-08-22 2015-11-04 信越化学工業株式会社 付加硬化型フロロシリコーンゴム組成物
DE102012016892A1 (de) 2012-08-24 2014-02-27 Be Innovative Gmbh Intraokularlinse, insbesondere Ziliarintraokularlinse
DE102012016893A1 (de) 2012-08-24 2014-05-15 Be Innovative Gmbh Intraokularlinse, insbesondere Kapselsackintraokularlinse
US9622855B2 (en) 2012-10-08 2017-04-18 Valdemar Portney Remote multifocal to monofocal optic conversion
US20140107459A1 (en) 2012-10-11 2014-04-17 Alcon Research, Ltd. Devices, systems, and methods for intraocular measurements
US9433497B2 (en) 2012-10-19 2016-09-06 1Co, Inc. Systems and methods for customizing adjustable intraocular lenses
US20140121768A1 (en) 2012-10-31 2014-05-01 Novartis Ag Accommodating intraocular lens with ciliary body activation
US20140135917A1 (en) 2012-11-13 2014-05-15 Vision Solutions Technologies, Inc. Multi-focus intraocular prosthesis
WO2014099345A1 (en) 2012-12-18 2014-06-26 Novartis Ag Presbyopia-correcting iol using curvature change of an air chamber
US9186244B2 (en) 2012-12-21 2015-11-17 Lensgen, Inc. Accommodating intraocular lens
WO2014099759A1 (en) 2012-12-21 2014-06-26 Novartis Ag Intraocular lens system for monofocal vision at multiple pre-defined focal points
CN104902848B (zh) 2012-12-21 2017-05-17 诺华股份有限公司 曲率变化调节性眼内镜片
US20140180406A1 (en) 2012-12-21 2014-06-26 Novartis Ag Accommodating intraocular lens
KR20150100646A (ko) 2012-12-21 2015-09-02 노바르티스 아게 곡률 변화 조절성 안구내 렌즈
US9925039B2 (en) 2012-12-26 2018-03-27 Rainbow Medical Ltd. Accommodative intraocular lens
US20140180407A1 (en) 2012-12-26 2014-06-26 Rainbow Medical Ltd. Accommodative intraocular lens
US20140309734A1 (en) 2012-12-26 2014-10-16 Rainbow Medical Ltd. Accommodative intraocular lens
US9486311B2 (en) 2013-02-14 2016-11-08 Shifamed Holdings, Llc Hydrophilic AIOL with bonding
US10327889B2 (en) 2013-02-28 2019-06-25 Richard F. Honigsbaum Tensioning rings for anterior capsules and accommodative intraocular lenses for use therewith
US20140257478A1 (en) 2013-03-07 2014-09-11 Sean J. McCafferty Accommodating fluidic intraocular lens with flexible interior membrane
US20140257479A1 (en) 2013-03-11 2014-09-11 Sean J. McCafferty Refocusable intraocular lens with flexible aspherical surface
EP3785668A1 (en) 2013-03-15 2021-03-03 Alcon Inc. Intraocular lens storage and loading devices and methods of use
US10195018B2 (en) 2013-03-21 2019-02-05 Shifamed Holdings, Llc Accommodating intraocular lens
CA3193600A1 (en) 2013-03-21 2014-09-25 Shifamed Holdings, Llc Accommodating intraocular lens
US9861469B2 (en) 2013-05-07 2018-01-09 Akkolens International B.V. Accommodating intraocular lens with haptics for sulcus fixation
WO2014197170A1 (en) 2013-06-03 2014-12-11 Clarvista Medical, Inc. Modular intraocular lens designs and methods
US10336913B2 (en) * 2013-08-28 2019-07-02 Dow Corning Toray Co., Ltd. Curable silicone composition, cured product thereof, and optical semiconductor device
EP2851038A1 (en) 2013-09-24 2015-03-25 Consejo Superior De Investigaciones Cientificas Intraocular lens with accomodation capacity
WO2015066502A1 (en) 2013-11-01 2015-05-07 Thomas Silvestrini Accomodating intraocular lens device
CN109806027A (zh) 2013-11-01 2019-05-28 雷恩斯根公司 双部件调节性人工晶状体设备
EP3071678A1 (en) * 2013-11-20 2016-09-28 Dow Corning Corporation Organosiloxane compositions
US9326846B2 (en) 2013-12-20 2016-05-03 Novartis Ag Accommodating intraocular lens
US20150173892A1 (en) 2013-12-23 2015-06-25 Novartis Ag Accommodating intraocular lens
AU2015219461B2 (en) 2014-02-18 2019-10-31 Alcon Inc. Modular intraocular lens designs, tools and methods
JP6410850B2 (ja) 2014-03-07 2018-10-24 コネクサス レンズ インコーポレイテッド 相互圧平性内面を有する再合焦可能なレンズシステム
US9333072B2 (en) 2014-04-29 2016-05-10 Chukyo Medical Co., Inc. Intraocular lens
US10004594B2 (en) 2014-06-19 2018-06-26 Omega Ophthalmics Llc Prosthetic capsular devices, systems, and methods
US10004596B2 (en) 2014-07-31 2018-06-26 Lensgen, Inc. Accommodating intraocular lens device
US20160051361A1 (en) 2014-08-21 2016-02-25 Emmetrope Incorporated Accommodating Intraocular Lens
AU2015306613B2 (en) 2014-08-26 2018-01-25 Shifamed Holdings, Llc Accommodating intraocular lens
US10265163B2 (en) 2014-12-27 2019-04-23 Jitander Dudee Accommodating intraocular lens assembly
ES3023708T3 (en) 2015-01-30 2025-06-03 Alcon Inc Inserter for inserting a base and a lens of a modular intraocular lens into an eye
US9358103B1 (en) 2015-02-10 2016-06-07 Omega Ophthalmics Llc Prosthetic capsular devices, systems, and methods
EP3217923B1 (en) 2015-02-16 2020-09-02 Alcon Inc. Curvature-changing, accommodative intraocular lenses with expandable peripheral reservoirs
US10478285B2 (en) 2015-03-03 2019-11-19 Novartis Ag Dual optic, curvature changing accommodative IOL
WO2016160952A1 (en) 2015-03-30 2016-10-06 Wendian Shi Fluid-filled implantable structures with internal surface-modifying components and related methods
ES2962463T3 (es) 2015-06-10 2024-03-19 Alcon Inc Materiales y componentes de lentes intraoculares
CA3002085A1 (en) 2015-11-04 2017-05-11 The Regents Of The University Of Colorado, A Body Corporate Modular intraocular lens designs, tools and methods
CN111407464B (zh) 2015-11-06 2022-12-13 爱尔康公司 可调节人工晶状体和制造方法
ES2617579B1 (es) 2015-11-16 2018-04-10 Lens Undergone Zonula Global, S.L. Lente intraocular acomodativa mejorada
CN108472129B (zh) 2015-11-18 2021-09-24 施菲姆德控股有限责任公司 组合的调节性人工晶状体
JP6900376B2 (ja) 2015-12-01 2021-07-07 レンスゲン、インコーポレイテッド 調節式眼内レンズデバイス
US9931202B2 (en) 2016-03-08 2018-04-03 Novartis Ag Dual optic, curvature changing accommodative IOL having a fixed disaccommodated refractive state
US11045309B2 (en) 2016-05-05 2021-06-29 The Regents Of The University Of Colorado Intraocular lens designs for improved stability
EP3463188B1 (en) 2016-05-27 2023-04-26 LensGen, Inc. Lens oil having a narrow molecular weight distribution for intraocular lens devices
JP2019520886A (ja) 2016-06-06 2019-07-25 オメガ・オフサルミックス・エルエルシーＯｍｅｇａ Ｏｐｈｔｈａｌｍｉｃｓ ＬＬＣ 人工水晶体嚢装置、システムおよび方法
US10159566B2 (en) 2016-09-26 2018-12-25 Novartis Ag Heat tunable intraocular lens
CA3109979C (en) 2016-10-21 2023-10-17 Omega Ophthalmics Llc Prosthetic capsular devices
CN110121313B (zh) 2016-10-28 2021-02-23 弗赛特影像6股份有限公司 可调节人工晶状体和植入方法
US10350056B2 (en) 2016-12-23 2019-07-16 Shifamed Holdings, Llc Multi-piece accommodating intraocular lenses and methods for making and using same
CN120000379A (zh) 2016-12-23 2025-05-16 施菲姆德控股有限责任公司 多片式调节性人工晶状体及其制造和使用方法
AU2018233971A1 (en) 2017-03-13 2019-10-03 Kejako Sa Accommodative lens device
US10918476B2 (en) 2017-03-30 2021-02-16 Verily Life Sciences Llc Electrowetting intraocular lens with isotonic aqueous phase
US11409134B2 (en) 2017-04-19 2022-08-09 Amo Groningen B.V. Electrowetting and photo curing for manufacturing of ophthalmic lenses
US11197752B2 (en) 2017-05-05 2021-12-14 Verily Life Sciences Llc Situ filling and sealing of electrowetting intraocular lenses
AU2018277037B2 (en) 2017-05-30 2024-04-18 Shifamed Holdings, Llc Surface treatments for accommodating intraocular lenses and associated methods and devices
AU2018279101B2 (en) 2017-06-07 2023-07-13 Shifamed Holdings, Llc Adjustable optical power intraocular lenses
US11382736B2 (en) 2017-06-27 2022-07-12 Alcon Inc. Injector, intraocular lens system, and related methods
US10716661B2 (en) 2017-07-17 2020-07-21 Verily Life Sciences Llc Accommodating intraocular lens with meniscus
WO2019027845A1 (en) 2017-07-31 2019-02-07 Douglas Michael Ackermann INTRAOCULAR LENS FOR PUPILARY ACCOMMODATION
US20190069989A1 (en) 2017-09-06 2019-03-07 Verily Life Sciences Llc Multipart electrowetting intraocular lens for in-situ assembly

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US10647831B2 (en) 2020-05-12
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WO2016049059A1 (en) 2016-03-31
US20200369853A1 (en) 2020-11-26
JP2017531471A (ja) 2017-10-26
EP3197462A4 (en) 2018-05-30

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