JP6654046B2 - Ｄｌｌ３結合試薬を含む治療薬及び診断薬の癌標的 - Google Patents

Ｄｌｌ３結合試薬を含む治療薬及び診断薬の癌標的 Download PDF

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JP6654046B2
JP6654046B2 JP2015556574A JP2015556574A JP6654046B2 JP 6654046 B2 JP6654046 B2 JP 6654046B2 JP 2015556574 A JP2015556574 A JP 2015556574A JP 2015556574 A JP2015556574 A JP 2015556574A JP 6654046 B2 JP6654046 B2 JP 6654046B2
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dll3
antibody
cancer
protein
antibodies
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JP2016513094A (ja
JP2016513094A5 (enExample
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リンジー ジェイン ハドソン
リンジー ジェイン ハドソン
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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JP2015556574A 2013-02-12 2014-02-12 Ｄｌｌ３結合試薬を含む治療薬及び診断薬の癌標的 Active JP6654046B2 (ja)

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Application Number Priority Date Filing Date Title
GBGB1302447.6A GB201302447D0 (en) 2013-02-12 2013-02-12 Therapeutic and diagnostic target
GB1302447.6 2013-02-12
PCT/GB2014/050407 WO2014125273A1 (en) 2013-02-12 2014-02-12 Therapeutic and diagnostic target for cancer comprising dll3 binding reagents

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JP2016513094A JP2016513094A (ja) 2016-05-12
JP2016513094A5 JP2016513094A5 (enExample) 2017-03-16
JP6654046B2 true JP6654046B2 (ja) 2020-02-26

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US (3) US20160032006A1 (enExample)
EP (2) EP2956483B1 (enExample)
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KR (1) KR102167550B1 (enExample)
CN (1) CN105143266B (enExample)
AU (1) AU2014217611B2 (enExample)
CA (1) CA2900134A1 (enExample)
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EA (1) EA034182B1 (enExample)
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Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104520324A (zh) 2012-02-24 2015-04-15 施特姆森特Rx股份有限公司 Dll3调节剂及其使用方法
JP2016531915A (ja) 2013-08-28 2016-10-13 ステムセントリックス， インコーポレイテッド 部位特異的抗体コンジュゲーション方法および組成物
CA2922544A1 (en) * 2013-08-28 2015-03-05 Stemcentrx, Inc. Engineered anti-dll3 conjugates and methods of use
EP3107576A4 (en) 2014-02-21 2017-09-06 Abbvie Stemcentrx LLC Anti-dll3 antibodies and drug conjugates for use in melanoma
ES2743809T3 (es) 2014-07-31 2020-02-20 Amgen Res Munich Gmbh Constructos de anticuerpo monocatenarios biespecificos específicos de especies cruzadas optimizados
ES2980787T3 (es) * 2014-07-31 2024-10-03 Amgen Res Munich Gmbh Constructo de anticuerpo de cadena sencilla biespecífico con distribución tisular potenciada
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