JP6630293B2 - 鉄欠乏症の治療方法 - Google Patents

鉄欠乏症の治療方法 Download PDF

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Publication number
JP6630293B2
JP6630293B2 JP2016573503A JP2016573503A JP6630293B2 JP 6630293 B2 JP6630293 B2 JP 6630293B2 JP 2016573503 A JP2016573503 A JP 2016573503A JP 2016573503 A JP2016573503 A JP 2016573503A JP 6630293 B2 JP6630293 B2 JP 6630293B2
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iron
biocompatible
iron oxide
group
rats
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Japanese (ja)
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JP2017524670A5 (OSRAM
JP2017524670A (ja
Inventor
チー−ロン チェン
チー−ロン チェン
ウェン−ユェン シェ
ウェン−ユェン シェ
チェン−シュエン リン
チェン−シュエン リン
スー−ヨウ リン
スー−ヨウ リン
シン−イー ファン
シン−イー ファン
ユェン−ホン スー
ユェン−ホン スー
シェン−ヂー ワン
シェン−ヂー ワン
シン ロン ファン
シン ロン ファン
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メガプロ バイオメディカル カンパニー リミテッド
メガプロ バイオメディカル カンパニー リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2016573503A 2014-07-11 2015-07-10 鉄欠乏症の治療方法 Active JP6630293B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462023533P 2014-07-11 2014-07-11
US62/023,533 2014-07-11
PCT/CN2015/083765 WO2016004894A1 (en) 2014-07-11 2015-07-10 Method of treating iron deficiency

Publications (3)

Publication Number Publication Date
JP2017524670A JP2017524670A (ja) 2017-08-31
JP2017524670A5 JP2017524670A5 (OSRAM) 2018-08-16
JP6630293B2 true JP6630293B2 (ja) 2020-01-15

Family

ID=53773226

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016573503A Active JP6630293B2 (ja) 2014-07-11 2015-07-10 鉄欠乏症の治療方法

Country Status (10)

Country Link
US (1) US9492399B2 (OSRAM)
EP (1) EP2965754B1 (OSRAM)
JP (1) JP6630293B2 (OSRAM)
CN (1) CN107073035B (OSRAM)
ES (1) ES2654429T3 (OSRAM)
HU (1) HUE035242T2 (OSRAM)
PL (1) PL2965754T3 (OSRAM)
PT (1) PT2965754T (OSRAM)
TW (1) TWI689310B (OSRAM)
WO (1) WO2016004894A1 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110157000B (zh) * 2018-02-12 2022-05-31 巨生生医股份有限公司 生物相容性磁性材料
JP2025537773A (ja) 2022-11-10 2025-11-20 ユニベルシテ ドゥ ロレーヌ 鉄ナノクラスター、それを得る方法及び鉄欠乏症への対処におけるその使用

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554386A (en) 1986-07-03 1996-09-10 Advanced Magnetics, Inc. Delivery of therapeutic agents to receptors using polysaccharides
US5248492A (en) 1986-07-03 1993-09-28 Advanced Magnetics, Inc. Low molecular weight carbohydrates as additives to stabilize metal oxide compositions
US6099852A (en) * 1998-09-23 2000-08-08 Johnson & Johnson Vision Products, Inc. Wettable silicone-based lenses
US6599498B1 (en) 1999-04-09 2003-07-29 Advanced Magnetics, Inc. Heat stable colloidal iron oxides coated with reduced carbohydrates and carbohdrate derivatives
US7871597B2 (en) 1999-04-09 2011-01-18 Amag Pharmaceuticals, Inc. Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents
US6997863B2 (en) * 2001-07-25 2006-02-14 Triton Biosystems, Inc. Thermotherapy via targeted delivery of nanoscale magnetic particles
US20030190355A1 (en) 2002-04-05 2003-10-09 Hermelin Marc S. Modified release minerals
MXPA05000799A (es) * 2002-07-24 2005-04-19 Hoffmann La Roche Derivados de aldehidos de polietilenglicol.
US7462446B2 (en) 2005-03-18 2008-12-09 University Of Washington Magnetic nanoparticle compositions and methods
MX2007016039A (es) 2005-06-17 2008-10-27 Univ North Carolina Metodos, sistemas y materiales de fabricacion de nanoparticulas.
DE102005059751A1 (de) 2005-12-09 2007-06-14 Ferropharm Gmbh Forschungslabor Wässrige Dispersion von superparamagnetischen Eindomänenteilchen, deren Herstellung und Verwendung zur Diagnose und Therapie
TWI293113B (en) 2005-12-23 2008-02-01 Ind Tech Res Inst Magnetic nanoparticles with fluorescent and specific targeting functions
EP3081219A1 (en) 2006-01-06 2016-10-19 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
TWI321133B (en) 2006-08-01 2010-03-01 Univ Kaohsiung Medical Folate-receptor-targeting iron oxide nanoparticles coated with poly(ethylene glycol)
ES2308901B1 (es) 2006-09-22 2009-10-30 Consejo Superior De Investigaciones Cientificas Sistemas que contienen nanoparticulas magneticas y polimeros, como nanocomposites y ferrofluidos, y sus aplicaciones.
US20110104073A1 (en) 2007-01-18 2011-05-05 Qi Zeng Iron/Iron Oxide Nanoparticle and Use Thereof
US20120003160A1 (en) 2007-06-29 2012-01-05 Amag Pharmaceuticals, Inc. Macrophage-Enhanced MRI (MEMRI) in a Single Imaging Session
TWI361082B (en) 2008-01-15 2012-04-01 Ind Tech Res Inst Biocompatible polymer and magnetic nanoparticle with biocompatibilities
WO2009120702A2 (en) 2008-03-25 2009-10-01 Emory University Elemental iron nanoparticles
EP2285423B1 (en) 2008-04-22 2020-03-18 MegaPro Biomedical Co., Ltd. Biocompatible polymer and magnetic nanoparticle with biocompatibility
US20090280063A1 (en) 2008-05-09 2009-11-12 General Electric Company Novel pei-peg graft copolymer coating of iron oxide nanoparticles for inflammation imaging
US8179999B2 (en) * 2008-08-08 2012-05-15 Nokia Corporation Decoding of blocks in radio communications
WO2010034319A1 (en) 2008-09-29 2010-04-01 Innovative Research And Development Co. (Inrad) Magnetite nanoparticles as a single dose treatment for iron deficiency anemia
BRPI0923859B8 (pt) 2008-12-29 2022-10-25 Gen Electric composição de agente de diagnóstico, e, método para a produção das nanopartículas
US8840868B2 (en) 2009-02-04 2014-09-23 The Regents Of The University Of Colorado, A Body Corporate Non-invasive detection of complement-mediated inflammation using CR2-targeted nanoparticles
EP2275137A1 (en) 2009-07-10 2011-01-19 Nanobiotix Metallic nanoparticles, preparation and uses thereof
GB2472446A (en) 2009-08-07 2011-02-09 Ct Fuer Angewandte Nanotechnologie Metal oxide particles coated with polyethylene glycol and their synthesis
US9327024B2 (en) 2009-10-30 2016-05-03 Tokyo Institute Of Technology Polymer coated ferrite fine particles and method for preparing polymer coated ferrite fine particles
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
WO2012092305A2 (en) 2010-12-27 2012-07-05 Incube Labs, Llc Nanonized iron compositions and methods of use thereof
EP2526927A1 (de) * 2011-05-25 2012-11-28 Justus-Liebig-Universität Gießen Biokompatible Nano- und Mikropartikel beschichtet mit Stabilisatoren für die pulmonale Applikation
CN102349930B (zh) 2011-11-01 2013-07-10 东南大学 具有抗氧化活性的氧化铁纳米粒水凝胶剂
US9474810B2 (en) 2012-03-02 2016-10-25 General Electric Company Superparamagnetic nanoparticles with PEG substituted α-hydroxy phosphonate shells
US9196405B2 (en) 2012-04-03 2015-11-24 Florida State University Research Foundation, Inc. Stable iron oxide nanoparticles and method of production
EP2647389A1 (en) * 2012-04-04 2013-10-09 Charité - Universitätsmedizin Berlin Magnetic nanoparticle dispersion, its preparation and diagnostic and therapeutic use
WO2013185032A1 (en) 2012-06-07 2013-12-12 President And Fellows Of Harvard College Nanotherapeutics for drug targeting
US20130336897A1 (en) 2012-06-18 2013-12-19 Gerald L. Wolf Theranosis of macrophage-associated diseases with ultrasmall superparamagnetic iron oxide nanoparticles (uspio)
CN103251648B (zh) 2013-05-15 2015-08-05 乔敏 治疗血磷酸盐过多症及缺铁性贫血症的铁基蒙脱石药物及其制备方法
CN103341165B (zh) 2013-05-31 2015-04-01 上海师范大学 一种具有光热功能的Fe@Fe3O4纳米粒子及其制备方法和应用
CN103303981B (zh) 2013-07-04 2015-04-01 厦门大学 一种四氧化三铁纳米粒子及其制备方法和用途
CN103405790B (zh) 2013-07-15 2015-05-20 中国科学院过程工程研究所 一种高分子原位修饰的超顺磁性颗粒、制备方法及其用途
CN103469290B (zh) 2013-09-02 2016-01-13 南阳师范学院 一种合成超顺磁性Fe3O4纳米晶的方法
CN103601900A (zh) 2013-11-15 2014-02-26 无锡中科光远生物材料有限公司 一种具有靶向效应的纳米颗粒的制备方法

Also Published As

Publication number Publication date
TW201625278A (zh) 2016-07-16
CN107073035B (zh) 2020-08-28
PL2965754T3 (pl) 2018-04-30
EP2965754B1 (en) 2017-10-04
US20160008292A1 (en) 2016-01-14
WO2016004894A1 (en) 2016-01-14
HUE035242T2 (en) 2018-05-02
PT2965754T (pt) 2018-01-08
JP2017524670A (ja) 2017-08-31
CN107073035A (zh) 2017-08-18
TWI689310B (zh) 2020-04-01
EP2965754A1 (en) 2016-01-13
US9492399B2 (en) 2016-11-15
ES2654429T3 (es) 2018-02-13

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