JP6606557B2 - Ｃ９ｏｒｆ７２発現を調節するための組成物 - Google Patents

Ｃ９ｏｒｆ７２発現を調節するための組成物 Download PDF

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JP6606557B2
JP6606557B2 JP2017546618A JP2017546618A JP6606557B2 JP 6606557 B2 JP6606557 B2 JP 6606557B2 JP 2017546618 A JP2017546618 A JP 2017546618A JP 2017546618 A JP2017546618 A JP 2017546618A JP 6606557 B2 JP6606557 B2 JP 6606557B2
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c9orf72
certain embodiments
antisense
compound
modified
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JP2018512127A (ja
JP2018512127A5 (enExample
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リゴ，フランク
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Ionis Pharmaceuticals Inc
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Ionis Pharmaceuticals Inc
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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JP2017546618A 2015-04-16 2016-04-15 Ｃ９ｏｒｆ７２発現を調節するための組成物 Expired - Fee Related JP6606557B2 (ja)

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US201562148691P 2015-04-16 2015-04-16
US62/148,691 2015-04-16
US201562232941P 2015-09-25 2015-09-25
US62/232,941 2015-09-25
US201562239400P 2015-10-09 2015-10-09
US62/239,400 2015-10-09
PCT/US2016/027747 WO2016168592A2 (en) 2015-04-16 2016-04-15 Compositions for modulating c9orf72 expression

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JP2019190648A Expired - Fee Related JP6924242B2 (ja) 2015-04-16 2019-10-18 Ｃ９ｏｒｆ７２発現を調節するための組成物
JP2021124953A Ceased JP2021184720A (ja) 2015-04-16 2021-07-30 Ｃ９ｏｒｆ７２発現を調節するための組成物

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CN (2) CN113265404A (enExample)
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JP7455831B2 (ja) * 2018-11-21 2024-03-26 アイオーニス ファーマシューティカルズ， インコーポレーテッド プリオン発現を低減するための化合物及び方法
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CN114072501A (zh) 2019-05-06 2022-02-18 马萨诸塞大学 抗c9orf72寡核苷酸及相关方法
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