CN113265404A - 用于调节c9orf72表达的组合物 - Google Patents

用于调节c9orf72表达的组合物 Download PDF

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CN113265404A
CN113265404A CN202110535254.3A CN202110535254A CN113265404A CN 113265404 A CN113265404 A CN 113265404A CN 202110535254 A CN202110535254 A CN 202110535254A CN 113265404 A CN113265404 A CN 113265404A
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certain embodiments
antisense
compound
c9orf72
nucleic acid
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Chinese (zh)
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F·里戈
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Ionis Pharmaceuticals Inc
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Ionis Pharmaceuticals Inc
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    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/35Nature of the modification
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    • C12N2310/3525MOE, methoxyethoxy
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CN202110535254.3A 2015-04-16 2016-04-15 用于调节c9orf72表达的组合物 Pending CN113265404A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562148691P 2015-04-16 2015-04-16
US62/148,691 2015-04-16
US201562232941P 2015-09-25 2015-09-25
US62/232,941 2015-09-25
US201562239400P 2015-10-09 2015-10-09
US62/239,400 2015-10-09
CN201680016814.1A CN107427532B (zh) 2015-04-16 2016-04-15 用于调节c9orf72表达的组合物

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