JP6478908B2 - 熱ショックタンパク質(HSP)90−βを調節することによる代謝症候群の治療方法 - Google Patents
熱ショックタンパク質(HSP)90−βを調節することによる代謝症候群の治療方法 Download PDFInfo
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- JP6478908B2 JP6478908B2 JP2015514227A JP2015514227A JP6478908B2 JP 6478908 B2 JP6478908 B2 JP 6478908B2 JP 2015514227 A JP2015514227 A JP 2015514227A JP 2015514227 A JP2015514227 A JP 2015514227A JP 6478908 B2 JP6478908 B2 JP 6478908B2
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- metabolic syndrome
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- 0 C*C(C(C12)*1C(C1=CC=C(C)*1*)=O)C(C)(C)NC2Oc(cc1)c(C)c(O2)c1C(*=C(*C(C)=*C(C1C(O3)=C(C)C(OC(C(*)C4OC(C(C)=CC=C(C)C)=O)OC(C)(C)C4OC)=CC1)=C(C)C3=O)*1C)=C1C2=O Chemical compound C*C(C(C12)*1C(C1=CC=C(C)*1*)=O)C(C)(C)NC2Oc(cc1)c(C)c(O2)c1C(*=C(*C(C)=*C(C1C(O3)=C(C)C(OC(C(*)C4OC(C(C)=CC=C(C)C)=O)OC(C)(C)C4OC)=CC1)=C(C)C3=O)*1C)=C1C2=O 0.000 description 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261652023P | 2012-05-25 | 2012-05-25 | |
| US61/652,023 | 2012-05-25 | ||
| PCT/US2013/042692 WO2013177535A2 (en) | 2012-05-25 | 2013-05-24 | Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015520170A JP2015520170A (ja) | 2015-07-16 |
| JP2015520170A5 JP2015520170A5 (enExample) | 2016-07-14 |
| JP6478908B2 true JP6478908B2 (ja) | 2019-03-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514227A Expired - Fee Related JP6478908B2 (ja) | 2012-05-25 | 2013-05-24 | 熱ショックタンパク質(HSP)90−βを調節することによる代謝症候群の治療方法 |
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| SG (1) | SG11201407775WA (enExample) |
| WO (1) | WO2013177535A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| HK1209035A1 (en) * | 2012-05-25 | 2016-03-24 | Berg Llc | Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta |
| CN111529534A (zh) | 2012-09-27 | 2020-08-14 | 儿童医学中心公司 | 用于治疗肥胖症的化合物和其使用方法 |
| CN117357538A (zh) * | 2014-03-26 | 2024-01-09 | 儿童医学中心公司 | 用于治疗肥胖症的雷公藤红素和衍生物 |
| EP3152307A4 (en) | 2014-06-06 | 2018-05-02 | Berg LLC | Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta |
| JP6779867B2 (ja) | 2014-06-13 | 2020-11-04 | ユマ セラピューティクス,インコーポレーテッド | ピリミジン化合物およびその使用方法 |
| WO2016149575A1 (en) * | 2015-03-19 | 2016-09-22 | Old Dominion University | Synergistic regulated cell death induction with hsp90 inhibitors and nanosecond pulsed electric fields |
| JP7034078B2 (ja) * | 2015-10-23 | 2022-03-11 | イーアールエックス ファーマシューティカルズ インコーポレイテッド | セラストロールの類似体 |
| CN105920018B (zh) * | 2016-06-15 | 2019-01-11 | 上海市内分泌代谢病研究所 | 雷公藤红素联合小檗碱制备治疗肥胖药物的用途 |
| CN107543929A (zh) * | 2016-06-23 | 2018-01-05 | 中国医学科学院肿瘤医院 | 基于蛋白标志物hsp90ab1诊断肺癌患者的试剂盒 |
| CN107028953A (zh) * | 2017-03-27 | 2017-08-11 | 北京大学 | 一种交感神经活性的刺激剂 |
| CA3061185A1 (en) * | 2017-04-24 | 2018-11-01 | Samus Therapeutics, Inc. | Hsp90 inhibitor oral formulations and related methods |
| WO2018235251A1 (ja) * | 2017-06-23 | 2018-12-27 | 株式会社ニコン | 解析装置、解析プログラム及び解析方法 |
| CN112156188A (zh) * | 2020-11-10 | 2021-01-01 | 上海交通大学医学院附属瑞金医院 | Hsp90作为制备预防与治疗类固醇糖尿病药物的用途 |
| CN113332308A (zh) * | 2021-02-22 | 2021-09-03 | 广东省妇幼保健院 | 调控hsp90 b1表达量的制剂在制备预防或治疗多囊卵巢综合征药物中的应用 |
| CN113160983A (zh) * | 2021-04-09 | 2021-07-23 | 南京医科大学附属逸夫医院 | 一种代谢相关脂肪性肝病临床预测模型 |
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| WO2004033657A2 (en) | 2002-10-07 | 2004-04-22 | Antigenics, Inc. | Heat shock protein binding fragments of cd91, and uses thereof |
| WO2004072080A1 (en) | 2003-02-10 | 2004-08-26 | Cellular Genomics, Inc. | Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of hsp90 complex activity |
| GB0309637D0 (en) | 2003-04-28 | 2003-06-04 | Cancer Rec Tech Ltd | Pyrazole compounds |
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| WO2005115431A2 (en) | 2004-05-24 | 2005-12-08 | Adonia Papathanassiu | Methods for inhibiting proteasome and heat shock protein 90 |
| WO2006020269A2 (en) | 2004-07-19 | 2006-02-23 | University Of Rochester | Biomarkers of neurodegenerative disease |
| US20060094682A1 (en) | 2004-10-29 | 2006-05-04 | Odyssey Thera, Inc. | Kinase inhibitors for the treatment of diabetes and obesity |
| US9120774B2 (en) | 2004-11-03 | 2015-09-01 | University Of Kansas | Novobiocin analogues having modified sugar moieties |
| FR2885904B1 (fr) | 2005-05-19 | 2007-07-06 | Aventis Pharma Sa | Nouveaux derives du fluorene, compositions les contenant et utilisation |
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| US8658633B2 (en) | 2006-02-16 | 2014-02-25 | Massachusetts Eye And Ear Infirmary | Methods and compositions for treating conditions of the eye |
| US20100015126A1 (en) | 2006-03-17 | 2010-01-21 | Martijn Frans Ben Gerard Gebbink | Methods of Binding of Cross-Beta Structures By Chaperones |
| WO2007137237A2 (en) | 2006-05-19 | 2007-11-29 | The Scripps Research Institute | Treatment of protein misfolding |
| US8318790B2 (en) | 2006-05-25 | 2012-11-27 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate HSP90 activity |
| CA2661436A1 (en) | 2006-08-24 | 2008-02-28 | Serenex, Inc. | Isoquinoline, quinazoline and phthalazine derivatives |
| WO2008024974A1 (en) | 2006-08-24 | 2008-02-28 | Serenex, Inc. | Pyrimidine and pyrazine derivatives |
| US9730912B2 (en) | 2006-10-12 | 2017-08-15 | Astex Therapeutics Limited | Pharmaceutical compounds |
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- 2013-05-24 HK HK15109711.2A patent/HK1209035A1/xx unknown
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- 2013-05-24 KR KR1020147035410A patent/KR20150010793A/ko not_active Withdrawn
- 2013-05-24 MX MX2014014188A patent/MX2014014188A/es unknown
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- 2013-05-24 AU AU2013266086A patent/AU2013266086B2/en not_active Ceased
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- 2013-05-24 CN CN201380039309.5A patent/CN104812898B/zh not_active Expired - Fee Related
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| WO2013177535A8 (en) | 2014-11-13 |
| AU2013266086B2 (en) | 2018-03-01 |
| US20170166891A1 (en) | 2017-06-15 |
| MX2014014188A (es) | 2015-05-11 |
| IL235910A0 (en) | 2015-01-29 |
| EP2854865B1 (en) | 2019-02-20 |
| US20140154266A1 (en) | 2014-06-05 |
| NZ702169A (en) | 2016-10-28 |
| EP2854865A4 (en) | 2016-03-02 |
| HK1209035A1 (en) | 2016-03-24 |
| CN104812898A (zh) | 2015-07-29 |
| WO2013177535A3 (en) | 2015-03-05 |
| US9533002B2 (en) | 2017-01-03 |
| CN104812898B (zh) | 2018-01-30 |
| AU2013266086A1 (en) | 2014-12-11 |
| JP2015520170A (ja) | 2015-07-16 |
| SG11201407775WA (en) | 2014-12-30 |
| CA2874676A1 (en) | 2013-11-28 |
| WO2013177535A2 (en) | 2013-11-28 |
| EP2854865A2 (en) | 2015-04-08 |
| KR20150010793A (ko) | 2015-01-28 |
| BR112014029301A2 (pt) | 2017-07-25 |
| EA201492184A1 (ru) | 2015-07-30 |
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