JP6431370B2 - 組換えＤｓｂＣを発現する細菌宿主系統 - Google Patents

組換えＤｓｂＣを発現する細菌宿主系統 Download PDF

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Publication number
JP6431370B2
JP6431370B2 JP2014519454A JP2014519454A JP6431370B2 JP 6431370 B2 JP6431370 B2 JP 6431370B2 JP 2014519454 A JP2014519454 A JP 2014519454A JP 2014519454 A JP2014519454 A JP 2014519454A JP 6431370 B2 JP6431370 B2 JP 6431370B2
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antibody
seq
protein
cell
gene
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JP2014521313A5 (enExample
JP2014521313A (ja
Inventor
エリス、マーク
ポール ハンフリーズ、デイビッド
ポール ハンフリーズ、デイビッド
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ユセベ ファルマ ソシエテ アノニム
ユセベ ファルマ ソシエテ アノニム
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2014519454A 2011-07-13 2012-07-13 組換えＤｓｂＣを発現する細菌宿主系統 Active JP6431370B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11173880 2011-07-13
EP11173880.3 2011-07-13
PCT/EP2012/002945 WO2013007388A1 (en) 2011-07-13 2012-07-13 Bacterial host strain expressing recombinant dsbc

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017209932A Division JP2018019719A (ja) 2011-07-13 2017-10-31 組換えＤｓｂＣを発現する細菌宿主系統

Publications (3)

Publication Number Publication Date
JP2014521313A JP2014521313A (ja) 2014-08-28
JP2014521313A5 JP2014521313A5 (enExample) 2017-03-09
JP6431370B2 true JP6431370B2 (ja) 2018-11-28

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JP2014519454A Active JP6431370B2 (ja) 2011-07-13 2012-07-13 組換えＤｓｂＣを発現する細菌宿主系統
JP2017209932A Pending JP2018019719A (ja) 2011-07-13 2017-10-31 組換えＤｓｂＣを発現する細菌宿主系統
JP2019200029A Active JP7062626B2 (ja) 2011-07-13 2019-11-01 組換えＤｓｂＣを発現する細菌宿主系統

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JP2017209932A Pending JP2018019719A (ja) 2011-07-13 2017-10-31 組換えＤｓｂＣを発現する細菌宿主系統
JP2019200029A Active JP7062626B2 (ja) 2011-07-13 2019-11-01 組換えＤｓｂＣを発現する細菌宿主系統

Country Status (27)

Country Link
US (2) US9725516B2 (enExample)
EP (2) EP3339325A1 (enExample)
JP (3) JP6431370B2 (enExample)
KR (1) KR102023786B1 (enExample)
CN (1) CN103649124B (enExample)
AU (1) AU2012283388B2 (enExample)
BR (1) BR112013032871B1 (enExample)
CA (1) CA2841824C (enExample)
CY (1) CY1119985T1 (enExample)
DK (1) DK2731973T3 (enExample)
EA (1) EA031449B1 (enExample)
ES (1) ES2659155T3 (enExample)
HR (1) HRP20180226T1 (enExample)
HU (1) HUE035674T2 (enExample)
IL (1) IL229947B (enExample)
IN (1) IN2014DN00202A (enExample)
LT (1) LT2731973T (enExample)
ME (1) ME02957B (enExample)
MX (1) MX348738B (enExample)
NO (1) NO2731973T3 (enExample)
PL (1) PL2731973T3 (enExample)
PT (1) PT2731973T (enExample)
RS (1) RS56926B1 (enExample)
SG (1) SG10201807560XA (enExample)
SI (1) SI2731973T1 (enExample)
SM (1) SMT201800068T1 (enExample)
WO (1) WO2013007388A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2020028299A (ja) * 2011-07-13 2020-02-27 ユセベ ファルマ ソシエテ アノニム 組換えＤｓｂＣを発現する細菌宿主系統

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KR101810778B1 (ko) * 2015-06-23 2017-12-20 서울대학교산학협력단 Cd154 결합 폴리펩타이드 및 그 용도
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CN109371049A (zh) * 2018-11-14 2019-02-22 天津大学 分子伴侣在促进单克隆抗体的形成和/或提高单克隆抗体的表达量中的应用
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020028299A (ja) * 2011-07-13 2020-02-27 ユセベ ファルマ ソシエテ アノニム 組換えＤｓｂＣを発現する細菌宿主系統
JP7062626B2 (ja) 2011-07-13 2022-05-17 ユセベ ファルマ ソシエテ アノニム 組換えＤｓｂＣを発現する細菌宿主系統

Also Published As

Publication number Publication date
CN103649124A (zh) 2014-03-19
JP2014521313A (ja) 2014-08-28
KR20140039240A (ko) 2014-04-01
DK2731973T3 (da) 2018-01-29
EP2731973B1 (en) 2017-11-15
PL2731973T3 (pl) 2018-04-30
BR112013032871A8 (pt) 2022-08-23
HRP20180226T1 (hr) 2018-03-09
US9957328B2 (en) 2018-05-01
EA201490274A1 (ru) 2014-05-30
BR112013032871B1 (pt) 2022-09-27
IL229947B (en) 2019-10-31
CA2841824C (en) 2021-07-13
RS56926B1 (sr) 2018-05-31
WO2013007388A1 (en) 2013-01-17
EP2731973A1 (en) 2014-05-21
MX348738B (es) 2017-06-27
CY1119985T1 (el) 2018-12-12
BR112013032871A2 (pt) 2017-01-24
AU2012283388A1 (en) 2014-01-09
JP2018019719A (ja) 2018-02-08
SG10201807560XA (en) 2018-10-30
IN2014DN00202A (enExample) 2015-06-05
KR102023786B1 (ko) 2019-09-20
CA2841824A1 (en) 2013-01-17
JP2020028299A (ja) 2020-02-27
SMT201800068T1 (it) 2018-03-08
SI2731973T1 (en) 2018-04-30
ES2659155T3 (es) 2018-03-14
US9725516B2 (en) 2017-08-08
PT2731973T (pt) 2018-02-22
MX2014000302A (es) 2014-02-17
US20140141468A1 (en) 2014-05-22
US20170335003A1 (en) 2017-11-23
EP3339325A1 (en) 2018-06-27
EA031449B1 (ru) 2019-01-31
LT2731973T (lt) 2018-02-26
ME02957B (me) 2018-07-20
NO2731973T3 (enExample) 2018-04-14
HK1194393A1 (zh) 2014-10-17
JP7062626B2 (ja) 2022-05-17
AU2012283388B2 (en) 2017-04-20
CN103649124B (zh) 2016-04-13
HUE035674T2 (en) 2018-05-28

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