HK1194393A1 - 表達重組 的細菌宿主菌株 - Google Patents

表達重組 的細菌宿主菌株

Info

Publication number
HK1194393A1
HK1194393A1 HK14107814.3A HK14107814A HK1194393A1 HK 1194393 A1 HK1194393 A1 HK 1194393A1 HK 14107814 A HK14107814 A HK 14107814A HK 1194393 A1 HK1194393 A1 HK 1194393A1
Authority
HK
Hong Kong
Prior art keywords
dsbc
bacterial host
host strain
expressing recombinant
strain expressing
Prior art date
Application number
HK14107814.3A
Other languages
English (en)
Inventor
．愛麗絲
．漢弗萊斯
Original Assignee
醫藥有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 醫藥有限公司 filed Critical 醫藥有限公司
Publication of HK1194393A1 publication Critical patent/HK1194393A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
HK14107814.3A 2011-07-13 2014-07-30 表達重組 的細菌宿主菌株 HK1194393A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11173880 2011-07-13
PCT/EP2012/002945 WO2013007388A1 (en) 2011-07-13 2012-07-13 Bacterial host strain expressing recombinant dsbc

Publications (1)

Publication Number Publication Date
HK1194393A1 true HK1194393A1 (zh) 2014-10-17

Family

ID=46545736

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14107814.3A HK1194393A1 (zh) 2011-07-13 2014-07-30 表達重組 的細菌宿主菌株

Country Status (27)

Country Link
US (2) US9725516B2 (zh)
EP (2) EP2731973B1 (zh)
JP (3) JP6431370B2 (zh)
KR (1) KR102023786B1 (zh)
CN (1) CN103649124B (zh)
AU (1) AU2012283388B2 (zh)
BR (1) BR112013032871B1 (zh)
CA (1) CA2841824C (zh)
CY (1) CY1119985T1 (zh)
DK (1) DK2731973T3 (zh)
EA (1) EA031449B1 (zh)
ES (1) ES2659155T3 (zh)
HK (1) HK1194393A1 (zh)
HR (1) HRP20180226T1 (zh)
HU (1) HUE035674T2 (zh)
IL (1) IL229947B (zh)
IN (1) IN2014DN00202A (zh)
LT (1) LT2731973T (zh)
ME (1) ME02957B (zh)
MX (1) MX348738B (zh)
NO (1) NO2731973T3 (zh)
PL (1) PL2731973T3 (zh)
PT (1) PT2731973T (zh)
RS (1) RS56926B1 (zh)
SG (1) SG10201807560XA (zh)
SI (1) SI2731973T1 (zh)
WO (1) WO2013007388A1 (zh)

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GB201000591D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201012599D0 (en) 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
JP6431370B2 (ja) * 2011-07-13 2018-11-28 ユセベ ファルマ ソシエテ アノニム 組換えＤｓｂＣを発現する細菌宿主系統
GB201208367D0 (en) 2012-05-14 2012-06-27 Ucb Pharma Sa Biological product
GB201223276D0 (en) * 2012-12-21 2013-02-06 Ucb Pharma Sa Antibodies and methods of producing same
BR112017013394B1 (pt) 2014-12-22 2024-02-06 Ucb Biopharma Sprl Método para fabricar proteína de interesse
KR101810778B1 (ko) * 2015-06-23 2017-12-20 서울대학교산학협력단 Cd154 결합 폴리펩타이드 및 그 용도
WO2017132298A1 (en) 2016-01-27 2017-08-03 Medimmune, Llc Methods for preparing antibodies with a defined glycosylation pattern
KR20210090645A (ko) * 2018-11-05 2021-07-20 제넨테크, 인크. 원핵 숙주 세포에서 2개의 사슬 단백질을 생산하는 방법
CN109371049A (zh) * 2018-11-14 2019-02-22 天津大学 分子伴侣在促进单克隆抗体的形成和/或提高单克隆抗体的表达量中的应用
WO2020188350A1 (en) 2019-03-18 2020-09-24 Bio-Rad Abd Serotec Gmbh Protection of spytag-containing periplasmic fusion proteins from protease tsp and ompt degradation
EP4010500A1 (de) * 2019-08-05 2022-06-15 Wacker Chemie AG Bakterienstamm zur freisetzung eines rekombinanten proteins in einem fermentationsverfahren

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Also Published As

Publication number Publication date
EP2731973A1 (en) 2014-05-21
ME02957B (me) 2018-07-20
AU2012283388B2 (en) 2017-04-20
DK2731973T3 (da) 2018-01-29
KR102023786B1 (ko) 2019-09-20
LT2731973T (lt) 2018-02-26
PL2731973T3 (pl) 2018-04-30
HUE035674T2 (en) 2018-05-28
US9725516B2 (en) 2017-08-08
EP3339325A1 (en) 2018-06-27
US20170335003A1 (en) 2017-11-23
CA2841824C (en) 2021-07-13
PT2731973T (pt) 2018-02-22
JP6431370B2 (ja) 2018-11-28
EA031449B1 (ru) 2019-01-31
ES2659155T3 (es) 2018-03-14
SG10201807560XA (en) 2018-10-30
BR112013032871A8 (pt) 2022-08-23
MX2014000302A (es) 2014-02-17
NO2731973T3 (zh) 2018-04-14
EA201490274A1 (ru) 2014-05-30
JP2018019719A (ja) 2018-02-08
KR20140039240A (ko) 2014-04-01
WO2013007388A1 (en) 2013-01-17
JP7062626B2 (ja) 2022-05-17
CN103649124B (zh) 2016-04-13
HRP20180226T1 (hr) 2018-03-09
IL229947B (en) 2019-10-31
MX348738B (es) 2017-06-27
IN2014DN00202A (zh) 2015-06-05
RS56926B1 (sr) 2018-05-31
CA2841824A1 (en) 2013-01-17
JP2020028299A (ja) 2020-02-27
JP2014521313A (ja) 2014-08-28
CY1119985T1 (el) 2018-12-12
SI2731973T1 (en) 2018-04-30
AU2012283388A1 (en) 2014-01-09
US9957328B2 (en) 2018-05-01
US20140141468A1 (en) 2014-05-22
CN103649124A (zh) 2014-03-19
BR112013032871A2 (pt) 2017-01-24
BR112013032871B1 (pt) 2022-09-27
EP2731973B1 (en) 2017-11-15

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