JP6403289B2 - 誘導体化３−スチリル−セファロスポリン - Google Patents
誘導体化３−スチリル−セファロスポリン Download PDFInfo
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- JP6403289B2 JP6403289B2 JP2016501556A JP2016501556A JP6403289B2 JP 6403289 B2 JP6403289 B2 JP 6403289B2 JP 2016501556 A JP2016501556 A JP 2016501556A JP 2016501556 A JP2016501556 A JP 2016501556A JP 6403289 B2 JP6403289 B2 JP 6403289B2
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- OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 description 1
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- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 229940001584 sodium metabisulfite Drugs 0.000 description 1
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- 235000011006 sodium potassium tartrate Nutrition 0.000 description 1
- MMUZXOWPDRLGBD-UXQCFNEQSA-M sodium;[(2s,5r)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl] sulfate Chemical compound [Na+].O=C([C@H]1N2C[C@@H](CC1)N(C2=O)OS(=O)(=O)[O-])NC1CCNCC1 MMUZXOWPDRLGBD-UXQCFNEQSA-M 0.000 description 1
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- 125000000547 substituted alkyl group Chemical group 0.000 description 1
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- 229910052717 sulfur Inorganic materials 0.000 description 1
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- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 description 1
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- JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical compound CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 description 1
- LBLYYCQCTBFVLH-UHFFFAOYSA-M toluenesulfonate group Chemical class C=1(C(=CC=CC1)S(=O)(=O)[O-])C LBLYYCQCTBFVLH-UHFFFAOYSA-M 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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| PCT/US2014/024503 WO2014165126A2 (en) | 2013-03-12 | 2014-03-12 | Derivatized 3-styryl-cephalosporins |
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| WO2009049086A1 (en) | 2007-10-09 | 2009-04-16 | Larry Sutton | Broad spectrum beta-lactamase inhibitors |
| ES2700575T3 (es) * | 2013-03-12 | 2019-02-18 | Gladius Pharmaceuticals Corp | 3-Estiril-cefalosporinas derivadas |
| EP3131497B1 (en) | 2014-04-16 | 2023-08-16 | ViaCyte, Inc. | Instruments for use with implantable encapsulation devices |
| WO2019070973A1 (en) * | 2017-10-04 | 2019-04-11 | Gladius Pharmaceuticals Corporation | CEPHAM COMPOUNDS HAVING LATENT REACTIVE GROUPS |
| EP3521269A1 (en) | 2018-02-06 | 2019-08-07 | Clariant Plastics & Coatings Ltd | Process for preparation of 1-nitrobenzene-2-alkyloxycarbonyl-5-carboxylic acid |
| WO2020071314A1 (ja) | 2018-10-03 | 2020-04-09 | 住友重機械工業株式会社 | ショベル |
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2014
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- 2014-03-12 EP EP14778768.3A patent/EP2968352B1/en not_active Not-in-force
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| US9975905B2 (en) | 2018-05-22 |
| WO2014165126A2 (en) | 2014-10-09 |
| US20160031906A1 (en) | 2016-02-04 |
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| WO2014165126A3 (en) | 2015-11-05 |
| EP3441071A1 (en) | 2019-02-13 |
| US20180319817A1 (en) | 2018-11-08 |
| EP2968352A2 (en) | 2016-01-20 |
| DK2968352T3 (da) | 2019-01-02 |
| CA2905240A1 (en) | 2014-10-09 |
| EP2968352A4 (en) | 2016-09-07 |
| ES2700575T3 (es) | 2019-02-18 |
| JP2018188454A (ja) | 2018-11-29 |
| JP2016512541A (ja) | 2016-04-28 |
| US11028103B2 (en) | 2021-06-08 |
| HK1220377A1 (en) | 2017-05-05 |
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