JP6352911B2 - 抗炎症活性を有するペプチド、及びそれを含む組成物 - Google Patents

抗炎症活性を有するペプチド、及びそれを含む組成物 Download PDF

Info

Publication number
JP6352911B2
JP6352911B2 JP2015521997A JP2015521997A JP6352911B2 JP 6352911 B2 JP6352911 B2 JP 6352911B2 JP 2015521997 A JP2015521997 A JP 2015521997A JP 2015521997 A JP2015521997 A JP 2015521997A JP 6352911 B2 JP6352911 B2 JP 6352911B2
Authority
JP
Japan
Prior art keywords
seq
peptide
inflammatory
western blot
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015521997A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015525768A (ja
JP2015525768A5 (enExample
Inventor
サン チェ キム
サン チェ キム
キョン ヘ キム
キョン ヘ キム
キュ−ヨン リ
キュ−ヨン リ
ソン−ホ コ
ソン−ホ コ
ポム チュン キム
ポム チュン キム
ヒョン−ヘ パク
ヒョン−ヘ パク
ソン チン フ
ソン チン フ
ウ チン リ
ウ チン リ
ファイン チャン
ファイン チャン
チョン スン ハ
チョン スン ハ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020120079096A external-priority patent/KR20140012385A/ko
Priority claimed from KR1020120089162A external-priority patent/KR20140022698A/ko
Priority claimed from KR1020120089167A external-priority patent/KR20140022699A/ko
Application filed by Individual filed Critical Individual
Publication of JP2015525768A publication Critical patent/JP2015525768A/ja
Publication of JP2015525768A5 publication Critical patent/JP2015525768A5/ja
Application granted granted Critical
Publication of JP6352911B2 publication Critical patent/JP6352911B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
JP2015521997A 2012-07-20 2013-03-15 抗炎症活性を有するペプチド、及びそれを含む組成物 Active JP6352911B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
KR10-2012-0079096 2012-07-20
KR1020120079096A KR20140012385A (ko) 2012-07-20 2012-07-20 항염증 활성을 갖는 펩티드 및 이를 포함하는 염증질환 치료용 조성물
KR10-2012-0089167 2012-08-14
KR10-2012-0089162 2012-08-14
KR10-2012-0089161 2012-08-14
KR20120089161 2012-08-14
KR1020120089162A KR20140022698A (ko) 2012-08-14 2012-08-14 텔로머라제 펩티드를 포함하는 염증 예방 또는 억제용 조성물
KR1020120089167A KR20140022699A (ko) 2012-08-14 2012-08-14 텔로머라제 펩티드를 포함하는 염증 예방 또는 억제용 조성물
KR10-2012-0104144 2012-09-19
KR20120104207 2012-09-19
KR10-2012-0104207 2012-09-19
KR20120104144 2012-09-19
PCT/EP2013/055326 WO2014012683A1 (en) 2012-07-20 2013-03-15 Anti-inflammatory peptides and composition comprising the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017077422A Division JP6514259B2 (ja) 2012-07-20 2017-04-10 抗炎症活性を有するペプチド、及びそれを含む組成物

Publications (3)

Publication Number Publication Date
JP2015525768A JP2015525768A (ja) 2015-09-07
JP2015525768A5 JP2015525768A5 (enExample) 2016-05-12
JP6352911B2 true JP6352911B2 (ja) 2018-07-04

Family

ID=47882177

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2015521997A Active JP6352911B2 (ja) 2012-07-20 2013-03-15 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2017077422A Active JP6514259B2 (ja) 2012-07-20 2017-04-10 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2019075635A Active JP6788062B2 (ja) 2012-07-20 2019-04-11 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2020181780A Active JP7128246B2 (ja) 2012-07-20 2020-10-29 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2022130519A Active JP7440581B2 (ja) 2012-07-20 2022-08-18 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2024021407A Active JP7741218B2 (ja) 2012-07-20 2024-02-15 抗炎症活性を有するペプチド、及びそれを含む組成物

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2017077422A Active JP6514259B2 (ja) 2012-07-20 2017-04-10 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2019075635A Active JP6788062B2 (ja) 2012-07-20 2019-04-11 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2020181780A Active JP7128246B2 (ja) 2012-07-20 2020-10-29 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2022130519A Active JP7440581B2 (ja) 2012-07-20 2022-08-18 抗炎症活性を有するペプチド、及びそれを含む組成物
JP2024021407A Active JP7741218B2 (ja) 2012-07-20 2024-02-15 抗炎症活性を有するペプチド、及びそれを含む組成物

Country Status (8)

Country Link
US (6) US20150125438A1 (enExample)
EP (3) EP3428182B1 (enExample)
JP (6) JP6352911B2 (enExample)
KR (2) KR102302392B1 (enExample)
CN (3) CN117551631A (enExample)
ES (2) ES2693321T3 (enExample)
TW (6) TWI700290B (enExample)
WO (1) WO2014012683A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3512417B2 (ja) 1993-09-29 2004-03-29 ザ ジレット カンパニー 安全カミソリ

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3046661T3 (en) 2012-05-11 2025-12-02 Gemvax & Kael Co Ltd Anti-inflammatory peptides and composition comprising the same
KR101799904B1 (ko) 2012-07-11 2017-11-22 주식회사 젬백스앤카엘 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물
US20150125438A1 (en) 2012-07-20 2015-05-07 Sang Jae Kim Anti-Inflammatory Peptides and Composition Comprising the Same
EP2899201B1 (en) 2012-09-19 2019-09-11 Gemvax & Kael Co., Ltd. Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate
WO2014046478A1 (ko) 2012-09-19 2014-03-27 주식회사 카엘젬백스 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물
WO2014151736A1 (en) * 2013-03-15 2014-09-25 Promega Corporation Activation of bioluminescence by structural complementation
EP4063863A1 (en) 2013-06-07 2022-09-28 Gemvax & Kael Co., Ltd. Gv1001, gemcitabine and capecitabine for use in the treatment of pancreatic cancer in high eotaxin baseline level patients
TWI539960B (zh) 2013-06-21 2016-07-01 凱爾傑姆維克斯有限公司 激素分泌調節劑、包括其的組成物以及其用途
EP3020724A4 (en) * 2013-07-12 2017-01-18 Gemvax & Kael Co., Ltd. Cell-penetrating peptide and conjugate comprising same
KR102359396B1 (ko) 2013-11-22 2022-02-08 주식회사 젬백스앤카엘 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물
WO2015093854A1 (ko) 2013-12-17 2015-06-25 주식회사 카엘젬백스 전립선 암 치료용 조성물
KR102373603B1 (ko) * 2014-04-11 2022-03-14 주식회사 젬백스앤카엘 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물
WO2015167067A1 (ko) * 2014-04-30 2015-11-05 주식회사 카엘젬백스 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법
EP3193906B1 (en) * 2014-09-18 2020-11-11 The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of Holy and Undiv. Trinity of Queen Elizabeth near Dublin Use of peptide inhibitors of il-36 proteolytic processing for the treatment and/or reduction of inflammation
KR102413243B1 (ko) 2014-12-23 2022-06-27 주식회사 젬백스앤카엘 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물
ES2799511T3 (es) 2015-02-27 2020-12-18 Gemvax & Kael Co Ltd Péptido para prevenir la pérdida de audición, y composición que lo comprende
KR101662438B1 (ko) * 2015-04-07 2016-10-04 가톨릭대학교 산학협력단 X형 구조의 dna를 유효성분으로 포함하는 아토피 피부염 예방 또는 치료용 조성물
KR101734529B1 (ko) 2015-05-08 2017-05-11 건국대학교 산학협력단 패혈증 치료제의 스크리닝 방법 및 패혈증 치료용 약학 조성물
WO2016190660A1 (ko) 2015-05-26 2016-12-01 주식회사 젬백스앤카엘 신규 펩티드 및 이를 포함한 조성물
US11015179B2 (en) 2015-07-02 2021-05-25 Gemvax & Kael Co., Ltd. Peptide having anti-viral effect and composition containing same
AU2016316774A1 (en) 2015-08-28 2018-03-22 The Medical College Of Wisconsin, Inc. Peptide inhibitors of telomerase translocation and therapeutic uses thereof
AU2016321333A1 (en) * 2015-09-09 2018-04-26 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with cerebro-craniofacial health
US10898540B2 (en) 2016-04-07 2021-01-26 Gem Vax & KAEL Co., Ltd. Peptide having effects of increasing telomerase activity and extending telomere, and composition containing same
KR101831888B1 (ko) * 2016-04-15 2018-04-16 (주)케어젠 항염증 활성을 갖는 펩타이드 및 이의 용도
KR101887577B1 (ko) * 2016-10-19 2018-09-10 (주)케어젠 항비만 및 항당뇨 효능을 갖는 펩타이드 및 이의 용도
AU2017382037B2 (en) * 2016-12-22 2022-03-10 Centre Hospitalier Universitaire De Montpellier New stapled-peptides and uses thereof
JP6601849B2 (ja) * 2017-08-21 2019-11-06 株式会社大一商会 遊技機
JP6601848B2 (ja) * 2017-08-21 2019-11-06 株式会社大一商会 遊技機
KR102092843B1 (ko) * 2018-08-30 2020-03-24 충남대학교 산학협력단 암 예방 또는 치료용 펩타이드 및 이의 용도
KR102274658B1 (ko) * 2018-11-16 2021-07-09 주식회사 카인사이언스 염증성 피부질환 치료용 펩타이드 및 이의 용도
KR102032945B1 (ko) * 2018-12-03 2019-10-16 순천대학교 산학협력단 항염증 활성을 나타내는 펩타이드 및 이를 유효성분으로 포함하는 항염증용 조성물
KR102146937B1 (ko) * 2018-12-11 2020-08-21 대한민국 왕사마귀로부터 유래된 테노데라신-1 펩타이드, 이를 유효성분으로 포함하는 항균, 항진균 또는 항염증용 조성물
KR102266613B1 (ko) * 2020-09-21 2021-06-18 자안바이오 주식회사 항염증 활성을 갖는 신규한 펩티드 및 이의 용도
EP4288149A1 (en) * 2021-02-08 2023-12-13 Bacoba AG Treatment of skin disorders
WO2023214802A1 (ko) * 2022-05-03 2023-11-09 한국생명공학연구원 신규 펩타이드 및 이의 항염 및 재생 용도
KR102827929B1 (ko) * 2023-01-26 2025-07-09 ㈜에빅스젠 신규한 뇌 질환 치료제 및 이의 용도

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
DE4330664A1 (de) * 1993-09-10 1995-03-16 Beiersdorf Ag Verwendungen von Pflanzenölen
ATE308554T1 (de) * 1994-07-07 2005-11-15 Geron Corp Säugetier-telomerase
SK176598A3 (en) * 1996-06-25 2000-06-12 Pfizer Indazole derivatives, pharmaceutical composition on their base and methods of treatment
CN102021153B (zh) * 1996-10-01 2016-05-25 杰龙公司 人类的端粒酶催化亚单位
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
KR100581990B1 (ko) * 1997-07-01 2006-05-23 캄비아 바이오시스템즈 엘엘씨 척추 동물 텔로머라제 유전자 및 단백질과 이의 용도
US7030211B1 (en) 1998-07-08 2006-04-18 Gemvax As Antigenic peptides derived from telomerase
US20030171280A1 (en) * 2001-07-31 2003-09-11 Soderstrom Karl Petter Compositions and methods for modulation of immune responses
JP2005502335A (ja) * 2001-08-08 2005-01-27 インサイト・ゲノミックス・インコーポレイテッド 細胞成長、分化および細胞死関連タンパク質
US8492438B2 (en) * 2002-04-26 2013-07-23 Asan Laboratories Company (Cayman), Limited Treatment skin disorders
AU2004236708A1 (en) * 2003-05-01 2004-11-18 Musc Foundation For Research Development An autologous upregulation mechanism allowing optimized cell type-specific and regulated gene expression cells
CN101011571A (zh) * 2006-03-13 2007-08-08 上海交通大学医学院 GADD45 β 蛋白及其抑制剂在类风湿关节炎中的应用
CA2665816C (en) * 2006-09-21 2016-07-12 Vaxil Biotherapeutics Ltd. Antigen specific multi epitope vaccines
MX2009003873A (es) * 2006-10-12 2009-04-22 Angeletti P Ist Richerche Bio Proteina de fusion de transcriptasa inversa de telomerasa, nucleotidos que la codifican y usos de la misma.
WO2008142376A1 (en) 2007-05-18 2008-11-27 Inhibox Ltd. Bicyclosulfonyl acid (bcsa) compounds and their use as therapeutic agents
WO2009025871A1 (en) * 2007-08-23 2009-02-26 University Of Medicine And Dentistry Of Nj Telomerase reverse transcriptase variant
GB2455539B (en) 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
WO2010003520A2 (en) 2008-06-16 2010-01-14 Genovax S.R.L. Anti-tumor immunotherapy
US8252282B2 (en) * 2008-06-19 2012-08-28 University Of Medicine & Dentistry Of New Jersey Nuclear telomerase reverse transcriptase variant
WO2010032322A1 (ja) 2008-09-22 2010-03-25 日清ファルマ株式会社 抗炎症性ペプチド
US20110318380A1 (en) 2008-10-01 2011-12-29 Dako Denmark A/S MHC Multimers in Cancer Vaccines and Immune Monitoring
ES2751092T3 (es) * 2010-02-16 2020-03-30 Ultimovacs Asa Polipéptidos
KR101284772B1 (ko) 2011-05-24 2013-07-17 정종문 항염증, 진통효과를 가지는 기능성 식품 조성물
KR20120133661A (ko) 2011-05-31 2012-12-11 주식회사 바이오포트코리아 아스타잔틴을 포함하는 항염증제
ES3046661T3 (en) 2012-05-11 2025-12-02 Gemvax & Kael Co Ltd Anti-inflammatory peptides and composition comprising the same
US20150125438A1 (en) 2012-07-20 2015-05-07 Sang Jae Kim Anti-Inflammatory Peptides and Composition Comprising the Same
EP2899201B1 (en) 2012-09-19 2019-09-11 Gemvax & Kael Co., Ltd. Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate
ES2743919T3 (es) 2012-09-19 2020-02-21 Gemvax & Kael Co Ltd Péptido de penetración celular, conjugado que comprende el mismo y composición que comprende el conjugado
WO2014046478A1 (ko) 2012-09-19 2014-03-27 주식회사 카엘젬백스 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물
EP4063863A1 (en) * 2013-06-07 2022-09-28 Gemvax & Kael Co., Ltd. Gv1001, gemcitabine and capecitabine for use in the treatment of pancreatic cancer in high eotaxin baseline level patients
EP3020724A4 (en) 2013-07-12 2017-01-18 Gemvax & Kael Co., Ltd. Cell-penetrating peptide and conjugate comprising same
WO2016190660A1 (ko) 2015-05-26 2016-12-01 주식회사 젬백스앤카엘 신규 펩티드 및 이를 포함한 조성물
TW201718028A (zh) 2015-10-13 2017-06-01 賽米克Ｉｐ有限責任公司 Ve-鈣黏蛋白結合性生物結合物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3512417B2 (ja) 1993-09-29 2004-03-29 ザ ジレット カンパニー 安全カミソリ

Also Published As

Publication number Publication date
US20210388328A1 (en) 2021-12-16
JP2015525768A (ja) 2015-09-07
US20170275603A1 (en) 2017-09-28
JP7128246B2 (ja) 2022-08-30
TW201938579A (zh) 2019-10-01
TWI658141B (zh) 2019-05-01
KR20150031413A (ko) 2015-03-24
US20240158768A1 (en) 2024-05-16
JP2017158561A (ja) 2017-09-14
TW201406957A (zh) 2014-02-16
JP2022166225A (ja) 2022-11-01
ES2871899T3 (es) 2021-11-02
JP2024056904A (ja) 2024-04-23
EP3896078A1 (en) 2021-10-20
EP3428182A3 (en) 2019-02-27
JP6788062B2 (ja) 2020-11-18
CN104470947B (zh) 2019-03-08
CN109777791B (zh) 2023-12-01
KR20200085927A (ko) 2020-07-15
EP3896078B1 (en) 2025-11-19
JP7440581B2 (ja) 2024-02-28
KR102302392B1 (ko) 2021-09-16
US11098294B2 (en) 2021-08-24
JP2021011502A (ja) 2021-02-04
US20200140832A1 (en) 2020-05-07
JP7741218B2 (ja) 2025-09-17
CN117551631A (zh) 2024-02-13
JP6514259B2 (ja) 2019-05-15
TWI700290B (zh) 2020-08-01
EP2875042A1 (en) 2015-05-27
EP2875042B1 (en) 2018-08-08
CN104470947A (zh) 2015-03-25
TWI779287B (zh) 2022-10-01
TW202237629A (zh) 2022-10-01
TWI836435B (zh) 2024-03-21
TW202417473A (zh) 2024-05-01
EP3428182B1 (en) 2021-04-21
EP3428182A2 (en) 2019-01-16
ES2693321T3 (es) 2018-12-11
TWI647311B (zh) 2019-01-11
CN109777791A (zh) 2019-05-21
US11905536B2 (en) 2024-02-20
TW201742921A (zh) 2017-12-16
TW202033540A (zh) 2020-09-16
JP2019151638A (ja) 2019-09-12
US20200208127A1 (en) 2020-07-02
EP3896078C0 (en) 2025-11-19
WO2014012683A1 (en) 2014-01-23
US20150125438A1 (en) 2015-05-07

Similar Documents

Publication Publication Date Title
JP7741218B2 (ja) 抗炎症活性を有するペプチド、及びそれを含む組成物
JP7007333B2 (ja) 抗炎症活性を有するペプチド、及びそれを含む組成物
KR20160086864A (ko) 항염증 활성을 갖는 펩티드 및 이를 포함하는 조성물

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160315

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20160315

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170110

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170410

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170912

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171212

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180508

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180607

R150 Certificate of patent or registration of utility model

Ref document number: 6352911

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250