JP6347468B2 - 組換えフォンウィルブランド因子の投与による凝固疾患の治療 - Google Patents

組換えフォンウィルブランド因子の投与による凝固疾患の治療 Download PDF

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JP6347468B2
JP6347468B2 JP2014514934A JP2014514934A JP6347468B2 JP 6347468 B2 JP6347468 B2 JP 6347468B2 JP 2014514934 A JP2014514934 A JP 2014514934A JP 2014514934 A JP2014514934 A JP 2014514934A JP 6347468 B2 JP6347468 B2 JP 6347468B2
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rvwf
fviii
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JP2014516088A5 (enExample
JP2014516088A (ja
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フリードリッヒ シャイフリンガー
フリードリッヒ シャイフリンガー
ペーター タレセク
ペーター タレセク
ブルース イーウェンスタイン
ブルース イーウェンスタイン
ウィン イェン ウォン
ウィン イェン ウォン
トビアス エム． スーター
トビアス エム． スーター
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バクスアルタ ゲーエムベーハー
バクスアルタ ゲーエムベーハー
バクスアルタ インコーポレイテッド
バクスアルタ インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014514934A 2011-06-10 2012-06-11 組換えフォンウィルブランド因子の投与による凝固疾患の治療 Active JP6347468B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161495884P 2011-06-10 2011-06-10
US61/495,884 2011-06-10
US201161511901P 2011-07-26 2011-07-26
US61/511,901 2011-07-26
US201161523790P 2011-08-15 2011-08-15
US61/523,790 2011-08-15
PCT/US2012/041957 WO2012171031A1 (en) 2011-06-10 2012-06-11 Treatment of coagulation disease by administration of recombinant vwf

Related Child Applications (1)

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JP2016137381A Division JP6527114B2 (ja) 2011-06-10 2016-07-12 組換えフォンウィルブランド因子の投与による凝固疾患の治療

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JP2014516088A JP2014516088A (ja) 2014-07-07
JP2014516088A5 JP2014516088A5 (enExample) 2015-07-30
JP6347468B2 true JP6347468B2 (ja) 2018-06-27

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JP2016137381A Active JP6527114B2 (ja) 2011-06-10 2016-07-12 組換えフォンウィルブランド因子の投与による凝固疾患の治療
JP2018246475A Pending JP2019048892A (ja) 2011-06-10 2018-12-28 組換えフォンウィルブランド因子の投与による凝固疾患の治療

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JP2018246475A Pending JP2019048892A (ja) 2011-06-10 2018-12-28 組換えフォンウィルブランド因子の投与による凝固疾患の治療

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US (3) US9272021B2 (enExample)
EP (3) EP3858375B1 (enExample)
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KR (3) KR20190041032A (enExample)
CN (3) CN108210889A (enExample)
AR (1) AR086904A1 (enExample)
AU (5) AU2012267458A1 (enExample)
BR (1) BR112013031795A2 (enExample)
CA (1) CA2838845C (enExample)
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ES (3) ES2682249T3 (enExample)
FI (1) FI3858375T3 (enExample)
HK (1) HK1257436A1 (enExample)
HR (1) HRP20180962T1 (enExample)
HU (1) HUE039317T2 (enExample)
LT (1) LT2717905T (enExample)
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PL (3) PL3858375T3 (enExample)
PT (3) PT2717905T (enExample)
RU (2) RU2680402C2 (enExample)
SG (2) SG10202002591QA (enExample)
SI (1) SI2717905T1 (enExample)
TR (1) TR201808823T4 (enExample)
WO (1) WO2012171031A1 (enExample)

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PT3412305T (pt) 2021-01-29
PT3858375T (pt) 2024-04-18
DK2717905T3 (en) 2018-07-02
AU2022201518A1 (en) 2022-03-24
US20160184403A1 (en) 2016-06-30
CN103732244A (zh) 2014-04-16
HUE039317T2 (hu) 2018-12-28
AU2020200026A1 (en) 2020-01-30
NZ618790A (en) 2015-07-31
PL3412305T3 (pl) 2021-05-31
KR101969515B1 (ko) 2019-04-16
PL3858375T3 (pl) 2024-05-20
FI3858375T3 (fi) 2024-04-17
TR201808823T4 (tr) 2018-07-23
EP2717905A1 (en) 2014-04-16
CN107412743A (zh) 2017-12-01
EP3858375A1 (en) 2021-08-04
MX350582B (es) 2017-09-11
CA2838845A1 (en) 2012-12-13
RU2628537C2 (ru) 2017-08-18
ES2860450T3 (es) 2021-10-05
AU2022201518B2 (en) 2025-07-03
CN107412743B (zh) 2021-07-02
AU2016202299B2 (en) 2017-07-20
CA2838845C (en) 2019-08-06
US9272021B2 (en) 2016-03-01
AU2017206235B2 (en) 2019-10-17
AU2016202299A1 (en) 2016-05-05
RU2017102679A3 (enExample) 2018-12-19
CN108210889A (zh) 2018-06-29
AU2017206235A1 (en) 2017-08-03
RU2019103386A3 (enExample) 2022-01-24
ES2682249T3 (es) 2018-09-19
HK1257436A1 (zh) 2019-10-18
WO2012171031A1 (en) 2012-12-13
RU2014100107A (ru) 2015-07-20
RU2019103386A (ru) 2020-08-07
PT2717905T (pt) 2018-07-02
JP2019048892A (ja) 2019-03-28
BR112013031795A2 (pt) 2016-12-20
AR086904A1 (es) 2014-01-29
DK3412305T3 (da) 2021-03-01
KR102319868B1 (ko) 2021-11-01
JP6527114B2 (ja) 2019-06-05
EP3412305B1 (en) 2021-01-06
KR20140039285A (ko) 2014-04-01
DK3858375T3 (da) 2024-04-15
EP2717905B1 (en) 2018-05-23
JP2017019788A (ja) 2017-01-26
HRP20180962T1 (hr) 2018-10-19
MX2020000083A (es) 2020-08-06
JP2014516088A (ja) 2014-07-07
ES2976169T3 (es) 2024-07-24
SI2717905T1 (sl) 2018-09-28
US20120316116A1 (en) 2012-12-13
LT2717905T (lt) 2018-10-10
KR20190041032A (ko) 2019-04-19
AU2012267458A1 (en) 2014-01-09
RU2680402C2 (ru) 2019-02-21
MX2013014543A (es) 2014-06-11
KR20200091476A (ko) 2020-07-30
EP3412305A1 (en) 2018-12-12
EP3858375B1 (en) 2024-03-20
US20250387455A1 (en) 2025-12-25
SG10201604684WA (en) 2016-07-28
SG10202002591QA (en) 2020-05-28
RU2017102679A (ru) 2018-12-19

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