JP6272694B2 - Ｏ−置換されたヒドロキシカルボン酸のエステルおよびその製造 - Google Patents

Ｏ−置換されたヒドロキシカルボン酸のエステルおよびその製造 Download PDF

Info

Publication number
JP6272694B2
JP6272694B2 JP2013521890A JP2013521890A JP6272694B2 JP 6272694 B2 JP6272694 B2 JP 6272694B2 JP 2013521890 A JP2013521890 A JP 2013521890A JP 2013521890 A JP2013521890 A JP 2013521890A JP 6272694 B2 JP6272694 B2 JP 6272694B2
Authority
JP
Japan
Prior art keywords
group
substituted
ester
branched
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2013521890A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013539457A5 (https=
JP2013539457A (ja
Inventor
デン リュー
デン リュー
ウォーレン ボーズ ネイル
ウォーレン ボーズ ネイル
ドゥレール ザビーヌ
ドゥレール ザビーヌ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastman Chemical Co
Original Assignee
Eastman Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Chemical Co filed Critical Eastman Chemical Co
Publication of JP2013539457A publication Critical patent/JP2013539457A/ja
Publication of JP2013539457A5 publication Critical patent/JP2013539457A5/ja
Application granted granted Critical
Publication of JP6272694B2 publication Critical patent/JP6272694B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • C07C67/11—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond being mineral ester groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/002—Aftershave preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
JP2013521890A 2010-07-29 2011-07-26 Ｏ−置換されたヒドロキシカルボン酸のエステルおよびその製造 Active JP6272694B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36885010P 2010-07-29 2010-07-29
US61/368,850 2010-07-29
US12/975,572 2010-12-22
US12/975,572 US8846723B2 (en) 2010-07-29 2010-12-22 Esters of O-substituted hydroxy carboxylic acids and preparations thereof
PCT/US2011/045303 WO2012015790A1 (en) 2010-07-29 2011-07-26 Esters of o-substituted hydroxy carboxylic acids and preparations thereof

Publications (3)

Publication Number Publication Date
JP2013539457A JP2013539457A (ja) 2013-10-24
JP2013539457A5 JP2013539457A5 (https=) 2014-08-14
JP6272694B2 true JP6272694B2 (ja) 2018-01-31

Family

ID=45527374

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013521890A Active JP6272694B2 (ja) 2010-07-29 2011-07-26 Ｏ−置換されたヒドロキシカルボン酸のエステルおよびその製造

Country Status (7)

Country Link
US (2) US8846723B2 (https=)
EP (1) EP2598471B1 (https=)
JP (1) JP6272694B2 (https=)
KR (1) KR101899606B1 (https=)
CN (2) CN105130865A (https=)
BR (1) BR112013001942B1 (https=)
WO (1) WO2012015790A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8613940B2 (en) 2010-09-03 2013-12-24 Eastman Chemical Company Carbonate derivatives as skin care
WO2012041395A1 (en) * 2010-10-01 2012-04-05 Loctite (R & D) Limited Alpha-cyanoacrylate ester synthesis
US8329938B2 (en) 2011-02-21 2012-12-11 Eastman Chemical Company Hydroxyalkanoic acid and hydroxyalkanoice acid oligomer esters of retinol
KR102634263B1 (ko) * 2015-12-01 2024-02-06 (주)아모레퍼시픽 신규 히드록시 피라논 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물
KR102463238B1 (ko) * 2015-12-01 2022-11-04 (주)아모레퍼시픽 신규 히드록시 피라논 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물
US10535506B2 (en) * 2016-01-13 2020-01-14 Mks Instruments, Inc. Method and apparatus for deposition cleaning in a pumping line
WO2018152428A1 (en) * 2017-02-17 2018-08-23 Illustris Pharmaceuticals, Inc. Compounds, compositions and use thereof
EP3801489A4 (en) 2018-06-05 2022-03-30 Flagship Pioneering Innovations V, Inc. ACYLATED DRUGS AND METHODS OF USE FOR THE TREATMENT OF AUTOIMMUNE DISEASES
EP3981397A1 (en) * 2020-10-08 2022-04-13 Global Scientific Tocotrienols derivates, methods and uses thereof

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH230446A (de) 1938-07-02 1943-12-31 Chem Ind Basel Verfahren zur Darstellung eines neuen Esters der Oxy-stilbenreihe.
US2302618A (en) * 1939-08-05 1942-11-17 Du Pont Preparation of organic esters
US2518456A (en) * 1946-04-19 1950-08-15 Martin L Fein Preparation of acyloxy carboxylic acids from esters of hydroxy carboxylic acids
US3682968A (en) 1969-06-25 1972-08-08 Merck & Co Inc Anti-inflammatory salicylic acid derivatives
US3980793A (en) 1972-03-13 1976-09-14 Astra Lakemedel Aktiebolag Carbonate esters of penicillins and compositions and methods for treatment of bacterial infections
GB1426869A (en) 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
US4107290A (en) 1972-06-29 1978-08-15 L'oreal Anti-solar polymers, method of making the same and cosmetic compositions containing the same
US4216224A (en) 1978-09-22 1980-08-05 Scott Eugene J Van Methods and compositions for treating psoriasis with retinoyl compounds
JPS61126069A (ja) * 1984-11-21 1986-06-13 Res Dev Corp Of Japan プロスタグランジン誘導体
ZW7487A1 (en) 1986-05-23 1987-12-16 Hoffmann La Roche Tetrahydronaphthaline and indane derivatives
US5750568A (en) 1986-06-11 1998-05-12 Procyon Pharmaceuticals, Inc. Protein kinase C Modulators. L.
GB8811410D0 (en) 1988-05-13 1988-06-15 Unilever Plc Treatment of skin disorders
ATE191444T1 (de) * 1993-12-15 2000-04-15 Avon Prod Inc Neue retinoidkonjugate zur behandlung von alterserscheinungen der haut
DE4415204A1 (de) 1994-04-30 1995-11-02 Carl Heinrich Dr Weischer Neue Retinol (Vitamin A) -Derivate, deren Herstellung und Verwendung als Arzneimittel und Kosmetika
JPH08337523A (ja) 1995-06-14 1996-12-24 Taiho Yakuhin Kogyo Kk 血管新生阻害剤
WO1997020812A1 (en) 1995-12-04 1997-06-12 Advanced Polymer Systems, Inc. RETINYL ESTERS OF α-HYDROXY ACIDS FOR TOPICAL IMPROVEMENT OF SKIN FUNCTION AND APPEARANCE
US6306818B1 (en) 1996-06-24 2001-10-23 Givaudan Roure (International) Sa Fragrance precursors
DE19631685A1 (de) 1996-08-06 1998-02-12 Wella Ag Hydrolytisch spaltbare Wirkstoffderivate, diese enthaltene Haarbehandlungsmittel und Verfahren zum Behandeln von Haaren
TW432055B (en) * 1997-05-16 2001-05-01 Ciba Sc Holding Ag Resorcinyl-triazines, their preparation process and a cosmetic composition containing them
FR2766176B1 (fr) 1997-07-15 1999-10-29 Caudalie Compositions a base de derives de resveratrol
DE19750526A1 (de) 1997-11-14 1999-05-20 Basf Ag Ascorbinsäurederivate enthaltende kosmetische und pharmazeutische Zubereitungen
WO1999040944A2 (en) 1998-02-12 1999-08-19 De Montfort University Hydroxylation activated drug release
DE19949284A1 (de) 1999-10-12 2001-04-19 Basf Ag Chirale Verbindung und deren Verwendung als chirale Dotierstoffe zur Herstellung von cholesterisch-flüssigkristallinen Zusammensetzungen
DE10016524A1 (de) 2000-04-03 2001-10-04 Basf Ag Polymerisierbare Flüssigkristalle
JP2001294558A (ja) * 2000-04-12 2001-10-23 Honshu Chem Ind Co Ltd ノルボルネンー２−カルボン酸エステル類及びその製造方法
JP2002193752A (ja) 2000-12-25 2002-07-10 Kanebo Ltd 毛髪処理剤
CN1455780A (zh) 2001-01-11 2003-11-12 株式会社开备传 新视黄醇衍生物、其制备方法和用途
US7091186B2 (en) 2001-09-24 2006-08-15 Seattle Genetics, Inc. p-Amidobenzylethers in drug delivery agents
AU2002333155A1 (en) 2001-10-30 2003-05-12 Pentapharm Ag Dermopharmaceutically and cosmetically active oligopeptides
DE10201223A1 (de) * 2002-01-15 2003-07-24 Knut Oppenlaender Neuartige Antioxidantien für Pharma und Kosmetik auf Basis von Phenolen, Polyphenolen und natürlichen Vitaminen und Verfahren zu ihrer Herstellung
AU2003233396B2 (en) 2002-03-13 2007-05-24 Thomas Skold Water-based delivery systems
ES2193874B1 (es) 2002-04-03 2005-03-01 Puleva Biotech, S.A. Compuestos naturales y derivados de estos para la prevencion y el tratamiento de enfermedades cardiovasculares, hepaticas, renales y cosmeticas.
CA2482940A1 (en) 2002-04-17 2003-10-23 Taisho Pharmaceuticals Co., Ltd. Hair growth tonic
ES2246603B1 (es) 2002-07-03 2007-06-16 Consejo Sup. De Investig. Cientificas Procedimiento para la preparacion de esteres de hidroxitirosol, esteres obtenidos y utilizacion.
US7985422B2 (en) 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
US7253212B2 (en) 2002-12-18 2007-08-07 Coreana Cosmetics Co., Ltd. Retinol derivative and cosmetic composition comprising the same
GB0306908D0 (en) 2003-03-26 2003-04-30 Angiogene Pharm Ltd Bioreductively activated stilbene prodrugs
US20040248762A1 (en) 2003-06-09 2004-12-09 Mcgee Thomas Malodor counteractant compositions
JP2005041871A (ja) 2003-07-10 2005-02-17 Taisho Pharmaceut Co Ltd ４置換ベンゼン化合物
US7357783B2 (en) 2003-07-17 2008-04-15 Medpro Safety Products, Inc. Safety system for a blood collection device
GB0319401D0 (en) 2003-08-19 2003-09-17 Univ Hull Materials
SI1506781T1 (https=) 2003-11-03 2005-08-31 Volkmann Peter Hansen
ES2233208B1 (es) 2003-11-27 2006-10-01 Puleva Biotech, S.A. Metodo para la preparacion enzimatica de compuestos antioxidantes.
GB0403115D0 (en) 2004-02-12 2004-03-17 Givauden Sa Organic compounds
GB0410134D0 (en) 2004-05-07 2004-06-09 Givaudan Sa Organic compounds
US7772352B2 (en) * 2005-01-28 2010-08-10 Bezwada Biomedical Llc Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices
EP1951260A4 (en) 2005-10-21 2009-11-11 Bezwada Biomedical Llc FUNCTIONALIZED PHENOLIC COMPOUNDS AND POURABLE ARTICLES THEREOF
WO2007054556A1 (de) 2005-11-11 2007-05-18 Æterna Zentaris Gmbh Neue pyridopyrazine und deren verwendung als modulatoren von kinasen
WO2007072503A2 (en) 2005-12-21 2007-06-28 Panacea Biotec Ltd. Combinations for managing inflammation and associated disorders
US7566795B2 (en) * 2006-10-06 2009-07-28 Eastman Chemical Company Preparation of retinyl esters
EP2109617A1 (en) 2007-02-05 2009-10-21 Nicox S.A. Nitric oxide releasing steroids
KR100829890B1 (ko) * 2007-02-08 2008-05-16 주식회사 바이오폴리메드 신규한 레티놀 유도체, 이의 제조방법 및 이를 포함하는주름 개선용 화장료 조성물
DE102007023869A1 (de) 2007-05-21 2008-12-18 Momentive Performance Materials Gmbh & Co. Kg Neue Polycarbonat- und/oder Polyurethan-Polyorganosiloxan-Verbindungen
DK2176208T3 (en) 2007-07-30 2015-04-27 Zynerba Pharmaceuticals Inc Prodrugs of cannabidiol, compositions containing prodrugs of cannabidiol and methods of use thereof
US20090035240A1 (en) 2007-07-31 2009-02-05 Maes Daniel H Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent
US20090035236A1 (en) 2007-07-31 2009-02-05 Maes Daniel H Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent
US8344024B2 (en) 2007-07-31 2013-01-01 Elc Management Llc Anhydrous cosmetic compositions containing resveratrol derivatives
US9295621B2 (en) 2007-07-31 2016-03-29 Elc Management Llc Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant
US8080583B2 (en) 2007-07-31 2011-12-20 Elc Management Llc Emulsion cosmetic compositions containing resveratrol derivatives and linear or branched silicone
FR2919800B1 (fr) 2007-08-06 2010-08-27 Biochimie Appliquee Solabia So Compositions cosmetiques et/ou dermatologiques contenant un ester de tyrosol ou d'hydroxytyrosol et d'acide gras insature, et leurs utilisations
US7927855B2 (en) 2007-08-08 2011-04-19 Eastman Chemical Company Esters of long-chain alcohols and preparation thereof
CN102617348B (zh) 2007-09-08 2016-05-18 Elc管理有限责任公司 阿魏酸白藜芦醇酯化合物、包含该化合物的组合物及其使用方法
JP2009079021A (ja) 2007-09-27 2009-04-16 Eiweiss Kk 新規化合物、光電子供与化合物およびこれらを含む光酸発生剤
EP2072494B1 (en) 2007-12-21 2010-12-01 Johnson & Johnson Consumer France SAS Cosmetic and pharmaceutical compositions
WO2009102418A1 (en) 2008-02-11 2009-08-20 University Of Washington Methods for the treatment and prevention of age-related retinal dysfunction
JP5597925B2 (ja) 2008-03-12 2014-10-01 Ｊｎｃ株式会社 重合性液晶組成物およびその用途
US20100316954A1 (en) * 2008-03-12 2010-12-16 Hiroshi Koyama Monomer having lactone skeleton, polymer compound and photoresist composition
US9707417B2 (en) 2008-06-25 2017-07-18 Basf Se Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions
CA2731477A1 (en) 2008-08-05 2010-02-11 Nicox S.A. New no releasing steroids derivatives
KR101039750B1 (ko) 2008-12-01 2011-06-09 한국생명공학연구원 신규 쿠마린계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 다약제내성 억제용 약학적 조성물
JP5398272B2 (ja) * 2009-01-09 2014-01-29 東京応化工業株式会社 レジスト組成物およびレジストパターン形成方法
WO2011041487A1 (en) 2009-09-30 2011-04-07 Innovotech, Llc Biocompatible and biodegradable polymers from renewable natural polyphenols
ES2444633T3 (es) 2010-04-21 2014-02-26 Firmenich Sa Carbonatos orgánicos con olor a vainilla

Also Published As

Publication number Publication date
BR112013001942B1 (pt) 2017-12-19
KR20130090409A (ko) 2013-08-13
BR112013001942A2 (pt) 2016-05-24
US20150025247A1 (en) 2015-01-22
CN103249709B (zh) 2016-01-06
CN103249709A (zh) 2013-08-14
US9532938B2 (en) 2017-01-03
WO2012015790A1 (en) 2012-02-02
EP2598471B1 (en) 2020-11-25
CN105130865A (zh) 2015-12-09
KR101899606B1 (ko) 2018-09-17
US20120029198A1 (en) 2012-02-02
EP2598471A1 (en) 2013-06-05
JP2013539457A (ja) 2013-10-24
US8846723B2 (en) 2014-09-30

Similar Documents

Publication Publication Date Title
JP6272694B2 (ja) Ｏ−置換されたヒドロキシカルボン酸のエステルおよびその製造
JP5474556B2 (ja) 有機溶媒中でリパーゼを用いる短鎖レチニルエステル及び長鎖酸又は長鎖エステルからの長鎖レチニルエステルの製造方法
JP2014524734A (ja) ベタインエステル並びにその製造及び使用方法
JP5443357B2 (ja) 長鎖アルコールのエステルとその製造方法
CN103228320B (zh) 用作护肤的碳酸酯衍生物
JP5960730B2 (ja) レチノールのヒドロキシアルカン酸及びヒドロキシアルカン酸オリゴマーエステル
WO2007126258A1 (en) The method of making optically active 2-halo-2-(n-substituted phenyl)acetic acid esters and 2-halo-2-(n-substituted phenyl)acetic acids by enzymatic method
US20110124064A1 (en) Esterification process of prostaglandins and analogues thereof
WO2007078176A1 (en) The method of making optically active 2-chloromandelic acid esters and 2-chloromandelic acids by enzymatic method
Matsumoto et al. Enzyme-mediated enantioselective hydrolysis of cyclic carbonates bearing an unsaturated substituent
JPH08275796A (ja) 光学活性シクロプロパン誘導体の製造法
JP2012503601A (ja) ４，５−二置換−オキシ−２−メチル−３，６−ジオキソ−シクロヘキサ−１，４−ジエニルアルキル酸のエステル及びその製造方法
JP2001275691A (ja) 光学活性β−イミノアルコール類、β−アミノアルコール類、製造中間体およびそれらの製造方法
JP2001278871A (ja) オキサゾリジン化合物およびその製造方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140630

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140630

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20150521

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150609

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150907

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20160216

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160517

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20160518

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20160609

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20160902

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170802

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180104

R150 Certificate of patent or registration of utility model

Ref document number: 6272694

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250