JP6262721B2 - 敗血症の予防用または治療用の組成物 - Google Patents

敗血症の予防用または治療用の組成物 Download PDF

Info

Publication number
JP6262721B2
JP6262721B2 JP2015511371A JP2015511371A JP6262721B2 JP 6262721 B2 JP6262721 B2 JP 6262721B2 JP 2015511371 A JP2015511371 A JP 2015511371A JP 2015511371 A JP2015511371 A JP 2015511371A JP 6262721 B2 JP6262721 B2 JP 6262721B2
Authority
JP
Japan
Prior art keywords
peptide
composition
sepsis
preventing
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015511371A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015518818A5 (enExample
JP2015518818A (ja
Inventor
サン チェ キム
サン チェ キム
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JP2015518818A publication Critical patent/JP2015518818A/ja
Publication of JP2015518818A5 publication Critical patent/JP2015518818A5/ja
Application granted granted Critical
Publication of JP6262721B2 publication Critical patent/JP6262721B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1276RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • C12Y207/07049RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Marine Sciences & Fisheries (AREA)
JP2015511371A 2012-05-11 2013-05-10 敗血症の予防用または治療用の組成物 Active JP6262721B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
KR10-2012-0050529 2012-05-11
KR20120050533 2012-05-11
KR20120050529 2012-05-11
KR10-2012-0050533 2012-05-11
KR20120071989 2012-07-02
KR10-2012-0071989 2012-07-02
KR20120104207 2012-09-19
KR10-2012-0104207 2012-09-19
PCT/KR2013/004145 WO2013169060A1 (ko) 2012-05-11 2013-05-10 패혈증 예방 또는 치료용 조성물

Publications (3)

Publication Number Publication Date
JP2015518818A JP2015518818A (ja) 2015-07-06
JP2015518818A5 JP2015518818A5 (enExample) 2016-06-30
JP6262721B2 true JP6262721B2 (ja) 2018-01-17

Family

ID=49551008

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015511371A Active JP6262721B2 (ja) 2012-05-11 2013-05-10 敗血症の予防用または治療用の組成物
JP2015511374A Active JP6262722B2 (ja) 2012-05-11 2013-05-10 関節リウマチの予防用または治療用組成物
JP2015511378A Active JP6267190B2 (ja) 2012-05-11 2013-05-10 悪液質の予防用または治療用組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015511374A Active JP6262722B2 (ja) 2012-05-11 2013-05-10 関節リウマチの予防用または治療用組成物
JP2015511378A Active JP6267190B2 (ja) 2012-05-11 2013-05-10 悪液質の予防用または治療用組成物

Country Status (6)

Country Link
US (3) US9907837B2 (enExample)
EP (3) EP2875824B1 (enExample)
JP (3) JP6262721B2 (enExample)
KR (3) KR101997756B1 (enExample)
CN (3) CN104507489B (enExample)
WO (3) WO2013169077A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022001591A (ja) * 2012-05-11 2022-01-06 ジェムバックス アンド カエル カンパニー,リミティド 抗炎症活性を有するペプチド、及びそれを含む組成物

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101997756B1 (ko) 2012-05-11 2019-07-08 주식회사 젬백스앤카엘 패혈증 예방 또는 치료용 조성물
KR101799904B1 (ko) 2012-07-11 2017-11-22 주식회사 젬백스앤카엘 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물
ES2716870T3 (es) 2013-04-19 2019-06-17 Gemvax & Kael Co Ltd Composición para el tratamiento y prevención de lesión isquémica
EP4063863A1 (en) 2013-06-07 2022-09-28 Gemvax & Kael Co., Ltd. Gv1001, gemcitabine and capecitabine for use in the treatment of pancreatic cancer in high eotaxin baseline level patients
TWI539960B (zh) * 2013-06-21 2016-07-01 凱爾傑姆維克斯有限公司 激素分泌調節劑、包括其的組成物以及其用途
CN105899224B (zh) 2013-10-23 2019-12-13 珍白斯凯尔有限公司 用于治疗和预防良性前列腺增生的组合物
KR102359396B1 (ko) 2013-11-22 2022-02-08 주식회사 젬백스앤카엘 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물
WO2015093854A1 (ko) 2013-12-17 2015-06-25 주식회사 카엘젬백스 전립선 암 치료용 조성물
KR102373603B1 (ko) 2014-04-11 2022-03-14 주식회사 젬백스앤카엘 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물
WO2015167067A1 (ko) 2014-04-30 2015-11-05 주식회사 카엘젬백스 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법
FI3177313T3 (fi) 2014-08-08 2023-02-28 Telomeraasi-käänteistranskriptaasipohjaisia hoitoja sydäninfarktiin liittyvien tilojen hoitamiseksi
KR102413243B1 (ko) 2014-12-23 2022-06-27 주식회사 젬백스앤카엘 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물
ES2799511T3 (es) 2015-02-27 2020-12-18 Gemvax & Kael Co Ltd Péptido para prevenir la pérdida de audición, y composición que lo comprende
US11015179B2 (en) 2015-07-02 2021-05-25 Gemvax & Kael Co., Ltd. Peptide having anti-viral effect and composition containing same
CN108431021B (zh) * 2015-11-03 2021-09-07 珍白斯凯尔有限公司 具有神经元损失预防和再生效果的肽以及包含该肽的组合物
KR101897121B1 (ko) * 2016-03-09 2018-09-10 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
US10898540B2 (en) 2016-04-07 2021-01-26 Gem Vax & KAEL Co., Ltd. Peptide having effects of increasing telomerase activity and extending telomere, and composition containing same
KR20200001730A (ko) * 2018-06-28 2020-01-07 차의과학대학교 산학협력단 김치를 포함하는 악액질 예방, 개선 또는 치료용 조성물
KR102276941B1 (ko) * 2018-07-03 2021-07-14 서울대학교산학협력단 류마티스 관절염 치료용 펩티드 및 그의 용도
EP4125863A1 (en) * 2020-04-03 2023-02-08 Medsenic Use of an arsenic compound for treating a short or long cytokine storm in various autoimmune/inflammatory diseases in humans or animals
KR102486196B1 (ko) * 2020-04-09 2023-01-06 대진대학교 산학협력단 무당벌레 유충 유래 펩타이드를 유효성분으로 포함하는 패혈증의 예방 또는 치료용 약제학적 조성물
KR20250025783A (ko) * 2023-08-14 2025-02-25 건국대학교 산학협력단 양배추은무늬밤나방 유충으로부터 분리된 세크로핀 펩타이드 및 그의 패혈증, 박테리아 감염증, 또는 염증성 질환의 치료 용도
KR20250145172A (ko) 2024-03-28 2025-10-13 한림대학교 산학협력단 암 악액질의 예방 또는 치료를 위한 약학 조성물

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998003180A2 (en) 1996-07-22 1998-01-29 The Victoria University Of Manchester Use of sex steroids function modulators to treat wounds and fibrotic disorders
CN102021153B (zh) * 1996-10-01 2016-05-25 杰龙公司 人类的端粒酶催化亚单位
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
TR199902800T2 (xx) 1997-05-15 2000-04-21 Chugai Seiyaku Kabushiki Kaisha Ka�eksiyi tedavi edici madde.
KR100581990B1 (ko) 1997-07-01 2006-05-23 캄비아 바이오시스템즈 엘엘씨 척추 동물 텔로머라제 유전자 및 단백질과 이의 용도
US7030211B1 (en) * 1998-07-08 2006-04-18 Gemvax As Antigenic peptides derived from telomerase
IL132406A0 (en) 1998-10-21 2001-03-19 Pfizer Prod Inc Treatment of bph with cgmp elevators
US6815426B2 (en) 2001-02-16 2004-11-09 E. I. Du Pont De Nemours And Company Angiogenesis-inhibitory tripeptides, compositions and their methods of use
US6622663B2 (en) 2001-03-27 2003-09-23 Exxonmobil Research And Engineering Company Fuel composition supply means for driving cycle conditions in spark ignition engines
CN1237969C (zh) 2001-04-10 2006-01-25 日本新药株式会社 慢性关节风湿病的治疗剂
WO2002092008A2 (en) 2001-05-16 2002-11-21 Yeda Research And Development Co., Ltd. Use of il-18 inhibitors for the treatement or prevention of sepsis
US20030143228A1 (en) 2001-10-29 2003-07-31 Baylor College Of Medicine Human telomerase reverse transcriptase as a class-II restricted tumor-associated antigen
WO2003084560A2 (en) 2002-04-10 2003-10-16 Applied Research Systems Ars Holding N.V. Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis
KR20050020987A (ko) 2002-06-12 2005-03-04 바이오겐 아이덱 엠에이 인코포레이티드 아데노신 수용체 길항제를 사용하여 허혈 재관류 손상을치료하는 방법
KR20050040517A (ko) 2003-10-29 2005-05-03 주식회사 오리엔트 허혈성 질환에 대한 저항성을 나타내는 형질전환 생쥐
PT1530965E (pt) 2003-11-11 2006-05-31 Udo Mattern Sistema de administracao de libertacao controlada de hormonas sexuais para aplicacao nasal
GB0426146D0 (en) 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
CA2646131C (en) * 2005-03-21 2018-09-04 Vicus Therapeutics Spe 1, Llc Compositions and methods for ameliorating cachexia
KR20080084818A (ko) 2005-11-25 2008-09-19 각고호우징 게이오기주크 전립선암 치료제
JP2009519033A (ja) 2005-12-16 2009-05-14 ディアト 核酸を細胞に送達するための細胞貫通ペプチド結合体
US20100168034A1 (en) 2006-02-20 2010-07-01 Ewha University-Industry Collaboration Foundation Peptide having cell membrane penetrating activity
EP2044108A4 (en) 2006-07-24 2010-06-30 Forhumantech Co Ltd PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND TREATMENT OF ISCHEMIC SUDIDS AND METHOD FOR THEIR ADMINISTRATION
EP2129682A4 (en) 2007-01-29 2011-07-20 Procell Therapeutics Inc NOVEL DOMAINS OF MACROMOLECULE TRANSDUCTION AND METHODS OF IDENTIFICATION AND USES THEREOF
BRPI0813002A2 (pt) 2007-06-29 2017-05-02 Correlogic Systems Inc marcadores preditivos para o câncer ovariano
US8933197B2 (en) 2007-08-15 2015-01-13 Amunix Operating Inc. Compositions comprising modified biologically active polypeptides
US20090136917A1 (en) 2007-10-25 2009-05-28 Szalay Aladar A Systems and methods for viral therapy
GB2455539B (en) 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
WO2010003520A2 (en) 2008-06-16 2010-01-14 Genovax S.R.L. Anti-tumor immunotherapy
KR101414854B1 (ko) 2008-07-08 2014-07-03 엘지전자 주식회사 디지털 텔레비전 및 디지털 텔레비전 시스템
ES2334315B1 (es) 2008-07-29 2011-02-28 Universitat Pompeu Fabra Peptidos con capacidad de penetracion celular y sus usos.
WO2010032322A1 (ja) 2008-09-22 2010-03-25 日清ファルマ株式会社 抗炎症性ペプチド
KR101169030B1 (ko) 2009-01-21 2012-07-26 애니젠 주식회사 신규한 세포막 투과 도메인 및 이를 포함하는 세포내 전달 시스템
US7928067B2 (en) 2009-05-14 2011-04-19 Ischemix Llc Compositions and methods for treating ischemia and ischemia-reperfusion injury
AU2010250452B2 (en) 2009-05-20 2014-06-05 Toray Industries, Inc. Cell membrane-permeable peptides
KR20110057049A (ko) 2009-11-23 2011-05-31 박의신 기능성 전립선염 치료제
KR20110062943A (ko) 2009-12-04 2011-06-10 주식회사종근당 퀴나졸린 유도체를 유효성분으로 하는 전립선 비대증 예방 또는 치료제
RU2611191C2 (ru) 2010-01-11 2017-02-21 Курна, Инк. Лечение заболеваний, связанных со связывающим половые гормоны глобулином (гспг), путем ингибирования природного антисмыслового транскрипта к гспг
ES2751092T3 (es) 2010-02-16 2020-03-30 Ultimovacs Asa Polipéptidos
FR2960542B1 (fr) 2010-05-27 2012-08-17 Esther Suzy Arlette Fellous Peptide en tant que medicament, en particulier pour le traitement du cancer
KR101263212B1 (ko) 2010-05-28 2013-05-10 성신여자대학교 산학협력단 신규한 세포막 투과성 펩타이드 및 그의 용도
WO2011150493A1 (en) 2010-05-30 2011-12-08 The Governing Council Of The University Of Toronto Mitochondrial penetrating peptides as carriers for antimicrobials
KR101348284B1 (ko) 2010-09-09 2014-01-03 주식회사 나이벡 인간 유래 세포 투과성 펩타이드와 생리활성 펩타이드 결합체 및 그 용도
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
KR20120121196A (ko) 2011-04-26 2012-11-05 주식회사 글루칸 관절염 치료제
KR101284772B1 (ko) 2011-05-24 2013-07-17 정종문 항염증, 진통효과를 가지는 기능성 식품 조성물
KR20120133661A (ko) 2011-05-31 2012-12-11 주식회사 바이오포트코리아 아스타잔틴을 포함하는 항염증제
KR101361445B1 (ko) 2011-12-26 2014-02-12 성균관대학교산학협력단 펩타이드, 5-플루오로우라실, 및 성숙수지상세포를 포함하는 암 치료용 약학적 조성물
JP5577472B2 (ja) 2012-02-10 2014-08-20 医療法人社団博心厚生会 単球増殖剤、単球増殖用培地、単球の製造方法、樹状細胞の製造方法、及び樹状細胞ワクチンの製造方法
WO2013135266A1 (en) 2012-03-12 2013-09-19 Gemvax As Treatment of non-small cell lung carcinoma by active immunotherapy
ES3046661T3 (en) * 2012-05-11 2025-12-02 Gemvax & Kael Co Ltd Anti-inflammatory peptides and composition comprising the same
KR101997756B1 (ko) 2012-05-11 2019-07-08 주식회사 젬백스앤카엘 패혈증 예방 또는 치료용 조성물
KR101799904B1 (ko) 2012-07-11 2017-11-22 주식회사 젬백스앤카엘 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물
ES2743919T3 (es) 2012-09-19 2020-02-21 Gemvax & Kael Co Ltd Péptido de penetración celular, conjugado que comprende el mismo y composición que comprende el conjugado
WO2014046478A1 (ko) 2012-09-19 2014-03-27 주식회사 카엘젬백스 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물
EP2899201B1 (en) 2012-09-19 2019-09-11 Gemvax & Kael Co., Ltd. Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate
ES2716870T3 (es) 2013-04-19 2019-06-17 Gemvax & Kael Co Ltd Composición para el tratamiento y prevención de lesión isquémica
EP4063863A1 (en) 2013-06-07 2022-09-28 Gemvax & Kael Co., Ltd. Gv1001, gemcitabine and capecitabine for use in the treatment of pancreatic cancer in high eotaxin baseline level patients
TWI539960B (zh) 2013-06-21 2016-07-01 凱爾傑姆維克斯有限公司 激素分泌調節劑、包括其的組成物以及其用途
CN105899224B (zh) 2013-10-23 2019-12-13 珍白斯凯尔有限公司 用于治疗和预防良性前列腺增生的组合物
KR102359396B1 (ko) 2013-11-22 2022-02-08 주식회사 젬백스앤카엘 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물
WO2015093854A1 (ko) 2013-12-17 2015-06-25 주식회사 카엘젬백스 전립선 암 치료용 조성물
KR102373603B1 (ko) 2014-04-11 2022-03-14 주식회사 젬백스앤카엘 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물
WO2015167067A1 (ko) 2014-04-30 2015-11-05 주식회사 카엘젬백스 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022001591A (ja) * 2012-05-11 2022-01-06 ジェムバックス アンド カエル カンパニー,リミティド 抗炎症活性を有するペプチド、及びそれを含む組成物
JP7449909B2 (ja) 2012-05-11 2024-03-14 ジェムバックス アンド カエル カンパニー,リミティド 抗炎症活性を有するペプチド、及びそれを含む組成物

Also Published As

Publication number Publication date
JP6262722B2 (ja) 2018-01-17
EP2875824A1 (en) 2015-05-27
WO2013169067A1 (ko) 2013-11-14
CN104487081B (zh) 2017-12-12
KR20150022798A (ko) 2015-03-04
CN104487081A (zh) 2015-04-01
CN104661672A (zh) 2015-05-27
JP2015517489A (ja) 2015-06-22
EP2875826A1 (en) 2015-05-27
KR20150022799A (ko) 2015-03-04
US20150175978A1 (en) 2015-06-25
KR101873773B1 (ko) 2018-08-02
EP2875826A4 (en) 2016-03-23
US9907837B2 (en) 2018-03-06
EP2875825A1 (en) 2015-05-27
KR20150022800A (ko) 2015-03-04
EP2875825A4 (en) 2016-03-23
WO2013169077A1 (ko) 2013-11-14
US9844584B2 (en) 2017-12-19
KR101997756B1 (ko) 2019-07-08
JP6267190B2 (ja) 2018-01-24
EP2875826B1 (en) 2017-08-23
EP2875824B1 (en) 2018-01-03
US20160008438A1 (en) 2016-01-14
EP2875824A4 (en) 2016-03-23
US20150353903A1 (en) 2015-12-10
US9730984B2 (en) 2017-08-15
EP2875825B1 (en) 2017-12-13
CN104661672B (zh) 2017-03-08
CN104507489B (zh) 2016-07-13
CN104507489A (zh) 2015-04-08
WO2013169060A1 (ko) 2013-11-14
JP2015518818A (ja) 2015-07-06
KR101997757B1 (ko) 2019-07-08
JP2015517488A (ja) 2015-06-22

Similar Documents

Publication Publication Date Title
JP6262721B2 (ja) 敗血症の予防用または治療用の組成物
KR102436084B1 (ko) 신규 펩티드 및 이를 포함한 조성물
US9937240B2 (en) Peptide having fibrosis inhibitory activity and composition containing same
JP6367950B2 (ja) 前立腺癌治療用組成物
JP6382972B2 (ja) 前立腺肥大治療用及びその予防用の組成物
AU2009309477B2 (en) Leukolectins and uses thereof
RS51704B (sr) Smeše i metodi za lečenje fibroznih poremećaja
TWI589594B (zh) 用以治療和/或預防自體免疫疾病和發炎疾病的短合成胜肽
DK2563806T3 (en) Human leukolectiner and uses thereof
WO2007085057A1 (en) A medical protocol
EP4218787A2 (en) Peptides for treating muscle atrophy
CA3059094A1 (en) C4bp-based compounds for treating immunological diseases
CA2328134A1 (en) The induction of antibiotic proteins and peptides by lait/scd14-protein
JP2014525236A (ja) 代謝障害、心障害及び免疫関連障害を治療するための方法における新規なペプチド、それを含む組成物及びそれらの使用
KR20190017868A (ko) Gm-csf 변이체 및 사용 방법
KR20220013612A (ko) Ps 펩타이드 유도체를 유효성분으로 포함하는 내독소혈증 또는 패혈증의 예방 또는 치료용 조성물
KR102232319B1 (ko) 텔로머라제 펩티드를 유효성분으로 포함하는 뇌혈관 질환 예방 또는 치료용 조성물
KR20160076556A (ko) 난소 기능 보존용 펩티드 및 이를 포함하는 조성물
JP2008519032A (ja) Fgf−20の調合物、生成方法および使用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160510

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20160510

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20170323

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A132

Effective date: 20170404

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20170703

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171003

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20171114

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20171214

R150 Certificate of patent or registration of utility model

Ref document number: 6262721

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250