JP6186277B2 - 抗her3抗体および組成物 - Google Patents

抗her3抗体および組成物 Download PDF

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Publication number
JP6186277B2
JP6186277B2 JP2013535578A JP2013535578A JP6186277B2 JP 6186277 B2 JP6186277 B2 JP 6186277B2 JP 2013535578 A JP2013535578 A JP 2013535578A JP 2013535578 A JP2013535578 A JP 2013535578A JP 6186277 B2 JP6186277 B2 JP 6186277B2
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antibody
her3
antibodies
light chain
composition
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Expired - Fee Related
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JP2013535578A
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JP2014503189A (ja
JP2014503189A5 (cg-RX-API-DMAC7.html
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ミッケル・ワンダール・ペダーセン
ヘレ・ヤコブセン
クラウス・ケーフェーズ
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Symphogen AS
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Symphogen AS
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013535578A 2010-11-01 2011-10-31 抗her3抗体および組成物 Expired - Fee Related JP6186277B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US40878210P 2010-11-01 2010-11-01
DKPA201000988 2010-11-01
DKPA201000988 2010-11-01
US61/408,782 2010-11-01
DKPA201100672 2011-09-05
DKPA201100672 2011-09-05
US201161531407P 2011-09-06 2011-09-06
US61/531,407 2011-09-06
PCT/IB2011/054835 WO2012059858A1 (en) 2010-11-01 2011-10-31 Anti-her3 antibodies and compositions

Publications (3)

Publication Number Publication Date
JP2014503189A JP2014503189A (ja) 2014-02-13
JP2014503189A5 JP2014503189A5 (cg-RX-API-DMAC7.html) 2014-12-18
JP6186277B2 true JP6186277B2 (ja) 2017-08-23

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Family Applications (2)

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JP2013535578A Expired - Fee Related JP6186277B2 (ja) 2010-11-01 2011-10-31 抗her3抗体および組成物
JP2013535577A Expired - Fee Related JP6033783B2 (ja) 2010-11-01 2011-10-31 Pan−her抗体組成物

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JP2013535577A Expired - Fee Related JP6033783B2 (ja) 2010-11-01 2011-10-31 Pan−her抗体組成物

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US (1) US9217039B2 (cg-RX-API-DMAC7.html)
EP (3) EP2635604B1 (cg-RX-API-DMAC7.html)
JP (2) JP6186277B2 (cg-RX-API-DMAC7.html)
KR (2) KR101862832B1 (cg-RX-API-DMAC7.html)
AU (2) AU2011324870B2 (cg-RX-API-DMAC7.html)
CA (2) CA2816520C (cg-RX-API-DMAC7.html)
DK (1) DK2635604T3 (cg-RX-API-DMAC7.html)
ES (2) ES2692379T3 (cg-RX-API-DMAC7.html)
IL (2) IL225953A0 (cg-RX-API-DMAC7.html)
MX (2) MX347981B (cg-RX-API-DMAC7.html)
PL (1) PL2635604T3 (cg-RX-API-DMAC7.html)
TW (1) TW201231066A (cg-RX-API-DMAC7.html)
WO (2) WO2012059858A1 (cg-RX-API-DMAC7.html)

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US9155802B2 (en) 2010-11-01 2015-10-13 Symphogen A/S Pan-HER antibody composition
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JP7654539B2 (ja) * 2018-09-07 2025-04-01 ファイザー・インク 抗αvβ8抗体、組成物及びその使用
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Also Published As

Publication number Publication date
AU2011324870A1 (en) 2013-01-31
MX2013004897A (es) 2013-07-15
US9217039B2 (en) 2015-12-22
MX348637B (es) 2017-06-22
CA2816520A1 (en) 2012-05-10
JP6033783B2 (ja) 2016-11-30
KR101862832B1 (ko) 2018-05-30
KR20140026336A (ko) 2014-03-05
AU2011324870B2 (en) 2015-01-29
AU2011324871A1 (en) 2013-05-09
US20130287684A1 (en) 2013-10-31
EP2635604B1 (en) 2016-11-30
JP2014503189A (ja) 2014-02-13
KR101773120B1 (ko) 2017-08-30
CA2816520C (en) 2017-11-21
EP2635605B1 (en) 2018-07-25
PL2635604T3 (pl) 2017-09-29
ES2616961T3 (es) 2017-06-14
EP2635604A2 (en) 2013-09-11
KR20140026337A (ko) 2014-03-05
CA2816519A1 (en) 2012-05-10
EP3156421A1 (en) 2017-04-19
IL225954A0 (en) 2013-07-31
IL225953A0 (en) 2013-07-31
MX2013004899A (es) 2013-07-15
WO2012059858A1 (en) 2012-05-10
CA2816519C (en) 2019-01-15
EP2635605A1 (en) 2013-09-11
JP2014503188A (ja) 2014-02-13
EP3156421B1 (en) 2018-06-06
DK2635604T3 (en) 2017-02-27
TW201231066A (en) 2012-08-01
ES2692379T3 (es) 2018-12-03
WO2012059857A2 (en) 2012-05-10
AU2011324871B2 (en) 2016-05-19
EP2635605A4 (en) 2014-10-22
WO2012059857A3 (en) 2012-07-19
MX347981B (es) 2017-05-22
IL225954B (en) 2018-05-31

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