JP6154809B2 - アルツハイマー病を示すマイクロｒｎａバイオマーカー - Google Patents

アルツハイマー病を示すマイクロｒｎａバイオマーカー Download PDF

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JP6154809B2
JP6154809B2 JP2014518915A JP2014518915A JP6154809B2 JP 6154809 B2 JP6154809 B2 JP 6154809B2 JP 2014518915 A JP2014518915 A JP 2014518915A JP 2014518915 A JP2014518915 A JP 2014518915A JP 6154809 B2 JP6154809 B2 JP 6154809B2
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ゾルタン デズソ，
ゾルタン デズソ，
パバン クマール，
パバン クマール，
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Eisai R&D Management Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2014518915A 2011-06-27 2012-06-26 アルツハイマー病を示すマイクロｒｎａバイオマーカー Active JP6154809B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161501720P 2011-06-27 2011-06-27
US61/501,720 2011-06-27
PCT/US2012/044202 WO2013003350A2 (en) 2011-06-27 2012-06-26 Microrna biomarkers indicative of alzheimer's disease

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JP2016150989A Division JP2016214256A (ja) 2011-06-27 2016-08-01 アルツハイマー病を示すマイクロｒｎａバイオマーカー

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JP2014520529A JP2014520529A (ja) 2014-08-25
JP2014520529A5 JP2014520529A5 (https=) 2015-08-13
JP6154809B2 true JP6154809B2 (ja) 2017-06-28

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JP2014518915A Active JP6154809B2 (ja) 2011-06-27 2012-06-26 アルツハイマー病を示すマイクロｒｎａバイオマーカー
JP2016150989A Pending JP2016214256A (ja) 2011-06-27 2016-08-01 アルツハイマー病を示すマイクロｒｎａバイオマーカー

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US (1) US9771617B2 (https=)
EP (1) EP2723894B1 (https=)
JP (2) JP6154809B2 (https=)
KR (1) KR102082016B1 (https=)
CN (1) CN103781919B9 (https=)
AU (1) AU2012275556B2 (https=)
BR (1) BR112013033488B8 (https=)
CA (1) CA2840196C (https=)
ES (1) ES2580379T3 (https=)
IL (1) IL230034B (https=)
MX (1) MX341840B (https=)
RU (1) RU2639509C2 (https=)
WO (1) WO2013003350A2 (https=)

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EP2723894A2 (en) 2014-04-30
WO2013003350A2 (en) 2013-01-03
KR102082016B1 (ko) 2020-02-26
AU2012275556A1 (en) 2013-05-02
MX341840B (es) 2016-09-05
AU2012275556B2 (en) 2016-02-04
CN103781919B9 (zh) 2017-09-15
ES2580379T3 (es) 2016-08-23
KR20140044375A (ko) 2014-04-14
BR112013033488B1 (pt) 2022-03-03
JP2014520529A (ja) 2014-08-25
CN103781919B (zh) 2017-07-04
IL230034B (en) 2021-02-28
CA2840196A1 (en) 2013-01-03
BR112013033488A2 (pt) 2017-03-01
WO2013003350A3 (en) 2013-04-11
US9771617B2 (en) 2017-09-26
MX2013015392A (es) 2014-07-14
JP2016214256A (ja) 2016-12-22
CN103781919A (zh) 2014-05-07
US20140378439A1 (en) 2014-12-25
EP2723894B1 (en) 2016-05-11
BR112013033488B8 (pt) 2022-11-22
RU2014102357A (ru) 2015-08-10
RU2639509C2 (ru) 2017-12-21
CA2840196C (en) 2022-09-20

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