JP6084571B2 - Ｃｎｓ７０５６（レミマゾラム）を用いた鎮静のための投薬レジメン - Google Patents

Ｃｎｓ７０５６（レミマゾラム）を用いた鎮静のための投薬レジメン Download PDF

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JP6084571B2
JP6084571B2 JP2013537044A JP2013537044A JP6084571B2 JP 6084571 B2 JP6084571 B2 JP 6084571B2 JP 2013537044 A JP2013537044 A JP 2013537044A JP 2013537044 A JP2013537044 A JP 2013537044A JP 6084571 B2 JP6084571 B2 JP 6084571B2
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cns7056
dose
fentanyl
sedation
additional
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JP2013541567A5 (enExample
JP2013541567A (ja
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カリン ヴィルヘルム−オグンビイ，
カリン ヴィルヘルム−オグンビイ，
キース ボルケット，
キース ボルケット，
ゲイリー スチュワート ティルブルック，
ゲイリー スチュワート ティルブルック，
ヒュー ウィルトシャイル，
ヒュー ウィルトシャイル，
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パイオン ユーケー リミテッド
パイオン ユーケー リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013537044A 2010-11-08 2011-11-07 Ｃｎｓ７０５６（レミマゾラム）を用いた鎮静のための投薬レジメン Active JP6084571B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP10014366 2010-11-08
EP10014366.8 2010-11-08
EP10014784.2 2010-11-19
EP10014784 2010-11-19
EP10014819.6 2010-11-22
EP10014819 2010-11-22
EP10014972.3 2010-11-25
EP10014972A EP2450039A1 (en) 2010-11-08 2010-11-25 Dosing regimen for sedation with CNS 7056 (Remimazolam)
PCT/EP2011/005581 WO2012062439A1 (en) 2010-11-08 2011-11-07 Dosing regimen for sedation with cns 7056 (remimazolam)

Publications (3)

Publication Number Publication Date
JP2013541567A JP2013541567A (ja) 2013-11-14
JP2013541567A5 JP2013541567A5 (enExample) 2014-11-06
JP6084571B2 true JP6084571B2 (ja) 2017-02-22

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JP2013537044A Active JP6084571B2 (ja) 2010-11-08 2011-11-07 Ｃｎｓ７０５６（レミマゾラム）を用いた鎮静のための投薬レジメン

Country Status (17)

Country Link
US (10) US9561236B2 (enExample)
EP (3) EP2450039A1 (enExample)
JP (1) JP6084571B2 (enExample)
KR (1) KR102059399B1 (enExample)
CN (1) CN103347519B (enExample)
AU (1) AU2011328497B8 (enExample)
DK (1) DK2637662T3 (enExample)
EA (1) EA024926B1 (enExample)
ES (1) ES2715179T3 (enExample)
HR (1) HRP20190447T1 (enExample)
HU (1) HUE044095T2 (enExample)
LT (1) LT2637662T (enExample)
PL (1) PL2637662T3 (enExample)
PT (1) PT2637662T (enExample)
RS (1) RS58577B1 (enExample)
SI (1) SI2637662T1 (enExample)
WO (1) WO2012062439A1 (enExample)

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