JP6045347B2 - ラサギリンの持続放出性製剤およびその使用 - Google Patents

ラサギリンの持続放出性製剤およびその使用 Download PDF

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Publication number
JP6045347B2
JP6045347B2 JP2012551732A JP2012551732A JP6045347B2 JP 6045347 B2 JP6045347 B2 JP 6045347B2 JP 2012551732 A JP2012551732 A JP 2012551732A JP 2012551732 A JP2012551732 A JP 2012551732A JP 6045347 B2 JP6045347 B2 JP 6045347B2
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pharmaceutical composition
rasagiline
total weight
pellets
active agent
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JP2013518870A (ja
JP2013518870A5 (https=
Inventor
ヨラム セラ
ヨラム セラ
ヌリット リヴナア
ヌリット リヴナア
イチャック ラメンスドルフ
イチャック ラメンスドルフ
トメール マドモン
トメール マドモン
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ファーマ ツー ビー リミテッド
ファーマ ツー ビー リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2012551732A 2010-02-03 2011-02-03 ラサギリンの持続放出性製剤およびその使用 Active JP6045347B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30101910P 2010-02-03 2010-02-03
US61/301,019 2010-02-03
PCT/IL2011/000126 WO2011095973A1 (en) 2010-02-03 2011-02-03 Extended release formulations of rasagiline and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016186945A Division JP6440662B2 (ja) 2010-02-03 2016-09-26 ラサギリンの持続放出性製剤およびその使用

Publications (3)

Publication Number Publication Date
JP2013518870A JP2013518870A (ja) 2013-05-23
JP2013518870A5 JP2013518870A5 (https=) 2014-03-20
JP6045347B2 true JP6045347B2 (ja) 2016-12-14

Family

ID=43896855

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012551732A Active JP6045347B2 (ja) 2010-02-03 2011-02-03 ラサギリンの持続放出性製剤およびその使用
JP2016186945A Active JP6440662B2 (ja) 2010-02-03 2016-09-26 ラサギリンの持続放出性製剤およびその使用
JP2018216973A Active JP6770564B2 (ja) 2010-02-03 2018-11-20 ラサギリンの持続放出性製剤およびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016186945A Active JP6440662B2 (ja) 2010-02-03 2016-09-26 ラサギリンの持続放出性製剤およびその使用
JP2018216973A Active JP6770564B2 (ja) 2010-02-03 2018-11-20 ラサギリンの持続放出性製剤およびその使用

Country Status (25)

Country Link
US (1) US9943489B2 (https=)
EP (2) EP2531181B1 (https=)
JP (3) JP6045347B2 (https=)
KR (1) KR101791715B1 (https=)
CN (1) CN102791258B (https=)
AU (1) AU2011212068B2 (https=)
BR (1) BR112012019374B1 (https=)
CA (1) CA2789006C (https=)
CL (1) CL2012002175A1 (https=)
CY (1) CY1121781T1 (https=)
DK (1) DK2531181T3 (https=)
ES (1) ES2733133T3 (https=)
HU (1) HUE044221T2 (https=)
IL (1) IL221274A (https=)
LT (1) LT2531181T (https=)
MX (1) MX354423B (https=)
NZ (1) NZ602111A (https=)
PL (1) PL2531181T3 (https=)
PT (1) PT2531181T (https=)
RS (1) RS58988B1 (https=)
RU (2) RU2734632C2 (https=)
SG (1) SG183150A1 (https=)
TR (1) TR201909277T4 (https=)
WO (1) WO2011095973A1 (https=)
ZA (1) ZA201206462B (https=)

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JP2017031189A (ja) * 2010-02-03 2017-02-09 ファーマ ツー ビー リミテッド ラサギリンの持続放出性製剤およびその使用

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CN102579367B (zh) * 2012-03-23 2014-03-12 中国人民解放军军事医学科学院毒物药物研究所 托吡酯缓释药物组合物、其制备方法及用途
WO2013139292A1 (zh) 2012-03-23 2013-09-26 中国人民解放军军事医学科学院毒物药物研究所 一种含辛弗林和托吡酯的联合产品
JP2015529196A (ja) * 2012-08-17 2015-10-05 テバ ファーマシューティカル インダストリーズ リミティド ラサギリンの非経口製剤
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017031189A (ja) * 2010-02-03 2017-02-09 ファーマ ツー ビー リミテッド ラサギリンの持続放出性製剤およびその使用

Also Published As

Publication number Publication date
AU2011212068A1 (en) 2012-09-20
CA2789006A1 (en) 2011-08-11
US20120301542A1 (en) 2012-11-29
US9943489B2 (en) 2018-04-17
RU2607595C2 (ru) 2017-01-10
SG183150A1 (en) 2012-09-27
CN102791258A (zh) 2012-11-21
IL221274A (en) 2017-05-29
JP2013518870A (ja) 2013-05-23
NZ602111A (en) 2014-10-31
CY1121781T1 (el) 2020-07-31
TR201909277T4 (tr) 2019-07-22
MX2012009079A (es) 2012-12-17
EP2531181A1 (en) 2012-12-12
RU2016141314A3 (https=) 2019-12-20
JP2019048855A (ja) 2019-03-28
PT2531181T (pt) 2019-07-17
WO2011095973A1 (en) 2011-08-11
IL221274A0 (en) 2012-10-31
EP3517103A1 (en) 2019-07-31
LT2531181T (lt) 2019-07-10
HUE044221T2 (hu) 2019-10-28
RU2016141314A (ru) 2018-12-14
PL2531181T3 (pl) 2019-09-30
RU2734632C2 (ru) 2020-10-21
KR20120130292A (ko) 2012-11-30
ES2733133T3 (es) 2019-11-27
RU2012136723A (ru) 2014-03-10
CA2789006C (en) 2018-11-27
MX354423B (es) 2018-03-02
AU2011212068B2 (en) 2016-08-18
KR101791715B1 (ko) 2017-10-30
EP2531181B1 (en) 2019-04-10
JP2017031189A (ja) 2017-02-09
JP6440662B2 (ja) 2018-12-19
ZA201206462B (en) 2014-02-26
CL2012002175A1 (es) 2013-01-11
RS58988B1 (sr) 2019-08-30
BR112012019374B1 (pt) 2022-01-11
BR112012019374A2 (pt) 2016-05-03
DK2531181T3 (da) 2019-07-15
JP6770564B2 (ja) 2020-10-14
CN102791258B (zh) 2018-05-08

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