CL2012002175A1 - Composicion farmaceutica oral de liberacion prolongada que comprende un agente activo de fracciones de propargilamina y aminoindano; metodo de preparacion; uso en el tratamiento de enfermedades neurodegenerativas o lesiones en el sistema nervioso tales como parkinson o alzheimer, un accidente cerebrovascular o lesion traumatica cerebral. - Google Patents
Composicion farmaceutica oral de liberacion prolongada que comprende un agente activo de fracciones de propargilamina y aminoindano; metodo de preparacion; uso en el tratamiento de enfermedades neurodegenerativas o lesiones en el sistema nervioso tales como parkinson o alzheimer, un accidente cerebrovascular o lesion traumatica cerebral.Info
- Publication number
- CL2012002175A1 CL2012002175A1 CL2012002175A CL2012002175A CL2012002175A1 CL 2012002175 A1 CL2012002175 A1 CL 2012002175A1 CL 2012002175 A CL2012002175 A CL 2012002175A CL 2012002175 A CL2012002175 A CL 2012002175A CL 2012002175 A1 CL2012002175 A1 CL 2012002175A1
- Authority
- CL
- Chile
- Prior art keywords
- propargilamine
- aminoindane
- parkinson
- lesions
- alzheimer
- Prior art date
Links
- XJEVHMGJSYVQBQ-UHFFFAOYSA-N 2,3-dihydro-1h-inden-1-amine Chemical compound C1=CC=C2C(N)CCC2=C1 XJEVHMGJSYVQBQ-UHFFFAOYSA-N 0.000 title abstract 2
- 208000030886 Traumatic Brain injury Diseases 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title abstract 2
- 230000003902 lesion Effects 0.000 title abstract 2
- 210000000653 nervous system Anatomy 0.000 title abstract 2
- 230000004770 neurodegeneration Effects 0.000 title abstract 2
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000002035 prolonged effect Effects 0.000 title abstract 2
- 230000009529 traumatic brain injury Effects 0.000 title abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30101910P | 2010-02-03 | 2010-02-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012002175A1 true CL2012002175A1 (es) | 2013-01-11 |
Family
ID=43896855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012002175A CL2012002175A1 (es) | 2010-02-03 | 2012-08-03 | Composicion farmaceutica oral de liberacion prolongada que comprende un agente activo de fracciones de propargilamina y aminoindano; metodo de preparacion; uso en el tratamiento de enfermedades neurodegenerativas o lesiones en el sistema nervioso tales como parkinson o alzheimer, un accidente cerebrovascular o lesion traumatica cerebral. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9943489B2 (https=) |
| EP (2) | EP2531181B1 (https=) |
| JP (3) | JP6045347B2 (https=) |
| KR (1) | KR101791715B1 (https=) |
| CN (1) | CN102791258B (https=) |
| AU (1) | AU2011212068B2 (https=) |
| BR (1) | BR112012019374B1 (https=) |
| CA (1) | CA2789006C (https=) |
| CL (1) | CL2012002175A1 (https=) |
| CY (1) | CY1121781T1 (https=) |
| DK (1) | DK2531181T3 (https=) |
| ES (1) | ES2733133T3 (https=) |
| HU (1) | HUE044221T2 (https=) |
| IL (1) | IL221274A (https=) |
| LT (1) | LT2531181T (https=) |
| MX (1) | MX354423B (https=) |
| NZ (1) | NZ602111A (https=) |
| PL (1) | PL2531181T3 (https=) |
| PT (1) | PT2531181T (https=) |
| RS (1) | RS58988B1 (https=) |
| RU (2) | RU2734632C2 (https=) |
| SG (1) | SG183150A1 (https=) |
| TR (1) | TR201909277T4 (https=) |
| WO (1) | WO2011095973A1 (https=) |
| ZA (1) | ZA201206462B (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP6045347B2 (ja) * | 2010-02-03 | 2016-12-14 | ファーマ ツー ビー リミテッド | ラサギリンの持続放出性製剤およびその使用 |
| CA2758556A1 (en) * | 2011-11-17 | 2013-05-17 | Pharmascience Inc. | Pharmaceutical composition of amphetamine mixed salts |
| LT2802319T (lt) * | 2012-01-12 | 2018-04-10 | Pharma Two B Ltd. | Fiksuotos dozės derinio terapija, skirta parkinsono ligai gydyti |
| US9504657B2 (en) * | 2012-01-12 | 2016-11-29 | Pharmatwob Ltd. | Fixed dose combination therapy of Parkinson's disease |
| CN103316026B (zh) | 2012-03-23 | 2016-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 含芬特明和托吡酯的联合产品及其制备方法 |
| CN102579367B (zh) * | 2012-03-23 | 2014-03-12 | 中国人民解放军军事医学科学院毒物药物研究所 | 托吡酯缓释药物组合物、其制备方法及用途 |
| WO2013139292A1 (zh) | 2012-03-23 | 2013-09-26 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种含辛弗林和托吡酯的联合产品 |
| JP2015529196A (ja) * | 2012-08-17 | 2015-10-05 | テバ ファーマシューティカル インダストリーズ リミティド | ラサギリンの非経口製剤 |
| WO2014192022A1 (en) * | 2013-05-20 | 2014-12-04 | Cadila Healthcare Limited | Pharmaceutical compositions of rasagiline |
| US20150275167A1 (en) * | 2014-03-28 | 2015-10-01 | Corning Incorporated | Composition and method for cell culture sustained release |
| AU2015317447B2 (en) * | 2014-09-15 | 2021-02-25 | Zevra Denmark A/S | Arimoclomol formulation |
| MX2019013666A (es) * | 2017-05-19 | 2020-08-20 | Biscayne Neurotherapeutics Inc | Composiciones farmacéuticas de liberación modificada de huperzina y métodos para usarlas. |
| CN107049985B (zh) * | 2017-06-07 | 2020-06-19 | 广州帝奇医药技术有限公司 | 一种抗帕金森病药物的长效缓释制剂及其制备方法 |
| BR112020021812A2 (pt) * | 2018-04-25 | 2021-02-23 | Neurocentria, Inc. | forma de dosagem, método para tratar uma doença, distúrbio, síndrome e/ou afecção em um paciente com necessidade do mesmo, e método para produzir uma forma de dosagem |
| CA3119361A1 (en) | 2018-11-19 | 2020-05-28 | Supernus Pharmaceuticals, Inc. | Use of higher doses of modified release huperzine formulations |
| TWI859242B (zh) * | 2019-05-31 | 2024-10-21 | 美商戴納立製藥公司 | 嘧啶基胺基-吡唑化合物之修飾釋放調配物及治療方法 |
| KR20210014289A (ko) | 2019-07-30 | 2021-02-09 | (주)비씨월드제약 | 라사길린을 함유하는 서방출성 미립구의 제조방법 |
| AR121619A1 (es) * | 2020-03-25 | 2022-06-22 | Inibsa Ginecologia S A | Una forma de dosificación oral de múltiples unidades de liberación modificada de succinato de doxilamina y clorhidrato de piridoxina y un procedimiento para su preparación |
| CN117355296A (zh) * | 2021-05-11 | 2024-01-05 | 阿德维斯尼公司 | 用于口服施用舒噻美的延长释放药物组合物 |
| EP4337176B1 (en) * | 2021-05-11 | 2025-07-16 | Advicenne | Prolonged-release pharmaceutical composition for oral administration of sultiame |
| CN118680910B (zh) * | 2024-08-26 | 2024-12-03 | 山东齐都药业有限公司 | 用于缓释递送雷沙吉兰甲磺酸盐的药物组合物及其制备方法和应用 |
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| EP2218444A3 (en) * | 2009-01-23 | 2010-08-25 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline formulation |
| JP6045347B2 (ja) * | 2010-02-03 | 2016-12-14 | ファーマ ツー ビー リミテッド | ラサギリンの持続放出性製剤およびその使用 |
-
2011
- 2011-02-03 JP JP2012551732A patent/JP6045347B2/ja active Active
- 2011-02-03 EP EP11707489.8A patent/EP2531181B1/en active Active
- 2011-02-03 BR BR112012019374-0A patent/BR112012019374B1/pt active IP Right Grant
- 2011-02-03 HU HUE11707489 patent/HUE044221T2/hu unknown
- 2011-02-03 EP EP19159171.8A patent/EP3517103A1/en not_active Withdrawn
- 2011-02-03 PL PL11707489T patent/PL2531181T3/pl unknown
- 2011-02-03 MX MX2012009079A patent/MX354423B/es active IP Right Grant
- 2011-02-03 US US13/577,099 patent/US9943489B2/en active Active
- 2011-02-03 CA CA2789006A patent/CA2789006C/en active Active
- 2011-02-03 KR KR1020127023006A patent/KR101791715B1/ko active Active
- 2011-02-03 RU RU2016141314A patent/RU2734632C2/ru active
- 2011-02-03 ES ES11707489T patent/ES2733133T3/es active Active
- 2011-02-03 DK DK11707489.8T patent/DK2531181T3/da active
- 2011-02-03 CN CN201180012590.4A patent/CN102791258B/zh active Active
- 2011-02-03 AU AU2011212068A patent/AU2011212068B2/en active Active
- 2011-02-03 RU RU2012136723A patent/RU2607595C2/ru active
- 2011-02-03 RS RS20190810A patent/RS58988B1/sr unknown
- 2011-02-03 WO PCT/IL2011/000126 patent/WO2011095973A1/en not_active Ceased
- 2011-02-03 SG SG2012057493A patent/SG183150A1/en unknown
- 2011-02-03 LT LTEP11707489.8T patent/LT2531181T/lt unknown
- 2011-02-03 NZ NZ602111A patent/NZ602111A/en not_active IP Right Cessation
- 2011-02-03 TR TR2019/09277T patent/TR201909277T4/tr unknown
- 2011-02-03 PT PT11707489T patent/PT2531181T/pt unknown
-
2012
- 2012-08-02 IL IL221274A patent/IL221274A/en active IP Right Grant
- 2012-08-03 CL CL2012002175A patent/CL2012002175A1/es unknown
- 2012-08-28 ZA ZA2012/06462A patent/ZA201206462B/en unknown
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2016
- 2016-09-26 JP JP2016186945A patent/JP6440662B2/ja active Active
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2018
- 2018-11-20 JP JP2018216973A patent/JP6770564B2/ja active Active
-
2019
- 2019-07-03 CY CY20191100699T patent/CY1121781T1/el unknown
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