IL221274A - Preparations containing prolonged-release resazilin and their use - Google Patents
Preparations containing prolonged-release resazilin and their useInfo
- Publication number
- IL221274A IL221274A IL221274A IL22127412A IL221274A IL 221274 A IL221274 A IL 221274A IL 221274 A IL221274 A IL 221274A IL 22127412 A IL22127412 A IL 22127412A IL 221274 A IL221274 A IL 221274A
- Authority
- IL
- Israel
- Prior art keywords
- rasagiline
- extended release
- release formulations
- formulations
- extended
- Prior art date
Links
- 238000013265 extended release Methods 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- RUOKEQAAGRXIBM-GFCCVEGCSA-N rasagiline Chemical compound C1=CC=C2[C@H](NCC#C)CCC2=C1 RUOKEQAAGRXIBM-GFCCVEGCSA-N 0.000 title 1
- 229960000245 rasagiline Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL221274A IL221274A (en) | 2010-02-03 | 2012-08-02 | Preparations containing prolonged-release resazilin and their use |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30101910P | 2010-02-03 | 2010-02-03 | |
| PCT/IL2011/000126 WO2011095973A1 (en) | 2010-02-03 | 2011-02-03 | Extended release formulations of rasagiline and uses thereof |
| IL221274A IL221274A (en) | 2010-02-03 | 2012-08-02 | Preparations containing prolonged-release resazilin and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL221274A0 IL221274A0 (en) | 2012-10-31 |
| IL221274A true IL221274A (en) | 2017-05-29 |
Family
ID=43896855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL221274A IL221274A (en) | 2010-02-03 | 2012-08-02 | Preparations containing prolonged-release resazilin and their use |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9943489B2 (https=) |
| EP (2) | EP2531181B1 (https=) |
| JP (3) | JP6045347B2 (https=) |
| KR (1) | KR101791715B1 (https=) |
| CN (1) | CN102791258B (https=) |
| AU (1) | AU2011212068B2 (https=) |
| BR (1) | BR112012019374B1 (https=) |
| CA (1) | CA2789006C (https=) |
| CL (1) | CL2012002175A1 (https=) |
| CY (1) | CY1121781T1 (https=) |
| DK (1) | DK2531181T3 (https=) |
| ES (1) | ES2733133T3 (https=) |
| HU (1) | HUE044221T2 (https=) |
| IL (1) | IL221274A (https=) |
| LT (1) | LT2531181T (https=) |
| MX (1) | MX354423B (https=) |
| NZ (1) | NZ602111A (https=) |
| PL (1) | PL2531181T3 (https=) |
| PT (1) | PT2531181T (https=) |
| RS (1) | RS58988B1 (https=) |
| RU (2) | RU2734632C2 (https=) |
| SG (1) | SG183150A1 (https=) |
| TR (1) | TR201909277T4 (https=) |
| WO (1) | WO2011095973A1 (https=) |
| ZA (1) | ZA201206462B (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6045347B2 (ja) * | 2010-02-03 | 2016-12-14 | ファーマ ツー ビー リミテッド | ラサギリンの持続放出性製剤およびその使用 |
| CA2758556A1 (en) * | 2011-11-17 | 2013-05-17 | Pharmascience Inc. | Pharmaceutical composition of amphetamine mixed salts |
| LT2802319T (lt) * | 2012-01-12 | 2018-04-10 | Pharma Two B Ltd. | Fiksuotos dozės derinio terapija, skirta parkinsono ligai gydyti |
| US9504657B2 (en) * | 2012-01-12 | 2016-11-29 | Pharmatwob Ltd. | Fixed dose combination therapy of Parkinson's disease |
| CN103316026B (zh) | 2012-03-23 | 2016-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 含芬特明和托吡酯的联合产品及其制备方法 |
| CN102579367B (zh) * | 2012-03-23 | 2014-03-12 | 中国人民解放军军事医学科学院毒物药物研究所 | 托吡酯缓释药物组合物、其制备方法及用途 |
| WO2013139292A1 (zh) | 2012-03-23 | 2013-09-26 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种含辛弗林和托吡酯的联合产品 |
| JP2015529196A (ja) * | 2012-08-17 | 2015-10-05 | テバ ファーマシューティカル インダストリーズ リミティド | ラサギリンの非経口製剤 |
| WO2014192022A1 (en) * | 2013-05-20 | 2014-12-04 | Cadila Healthcare Limited | Pharmaceutical compositions of rasagiline |
| US20150275167A1 (en) * | 2014-03-28 | 2015-10-01 | Corning Incorporated | Composition and method for cell culture sustained release |
| AU2015317447B2 (en) * | 2014-09-15 | 2021-02-25 | Zevra Denmark A/S | Arimoclomol formulation |
| MX2019013666A (es) * | 2017-05-19 | 2020-08-20 | Biscayne Neurotherapeutics Inc | Composiciones farmacéuticas de liberación modificada de huperzina y métodos para usarlas. |
| CN107049985B (zh) * | 2017-06-07 | 2020-06-19 | 广州帝奇医药技术有限公司 | 一种抗帕金森病药物的长效缓释制剂及其制备方法 |
| BR112020021812A2 (pt) * | 2018-04-25 | 2021-02-23 | Neurocentria, Inc. | forma de dosagem, método para tratar uma doença, distúrbio, síndrome e/ou afecção em um paciente com necessidade do mesmo, e método para produzir uma forma de dosagem |
| CA3119361A1 (en) | 2018-11-19 | 2020-05-28 | Supernus Pharmaceuticals, Inc. | Use of higher doses of modified release huperzine formulations |
| TWI859242B (zh) * | 2019-05-31 | 2024-10-21 | 美商戴納立製藥公司 | 嘧啶基胺基-吡唑化合物之修飾釋放調配物及治療方法 |
| KR20210014289A (ko) | 2019-07-30 | 2021-02-09 | (주)비씨월드제약 | 라사길린을 함유하는 서방출성 미립구의 제조방법 |
| AR121619A1 (es) * | 2020-03-25 | 2022-06-22 | Inibsa Ginecologia S A | Una forma de dosificación oral de múltiples unidades de liberación modificada de succinato de doxilamina y clorhidrato de piridoxina y un procedimiento para su preparación |
| CN117355296A (zh) * | 2021-05-11 | 2024-01-05 | 阿德维斯尼公司 | 用于口服施用舒噻美的延长释放药物组合物 |
| EP4337176B1 (en) * | 2021-05-11 | 2025-07-16 | Advicenne | Prolonged-release pharmaceutical composition for oral administration of sultiame |
| CN118680910B (zh) * | 2024-08-26 | 2024-12-03 | 山东齐都药业有限公司 | 用于缓释递送雷沙吉兰甲磺酸盐的药物组合物及其制备方法和应用 |
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| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4415547A (en) * | 1982-06-14 | 1983-11-15 | Sterling Drug Inc. | Sustained-release pharmaceutical tablet and process for preparation thereof |
| US4861800A (en) | 1987-08-18 | 1989-08-29 | Buyske Donald A | Method for administering the drug deprenyl so as to minimize the danger of side effects |
| HU208484B (en) | 1988-08-17 | 1993-11-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia |
| IL92952A (en) | 1990-01-03 | 1994-06-24 | Teva Pharma | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
| US5744500A (en) | 1990-01-03 | 1998-04-28 | Teva Pharmaceutical Industries, Ltd. | Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof |
| US5225446A (en) | 1990-08-31 | 1993-07-06 | Deprenyl Animal Health, Inc. | Use of 1-deprenyl for retention of specific physiological functions |
| US5151449A (en) | 1990-08-31 | 1992-09-29 | Deprenyl Animal Health, Inc. | Use of L-deprenyl for retention of specific physiological functions |
| CA2039194C (en) | 1990-08-31 | 1997-01-28 | Norton W. Milgram | Uses of l-deprenyl and compositions for same |
| US5192808A (en) | 1990-08-31 | 1993-03-09 | Deprenyl Animal Health, Inc. | Therapeutic effect of L-deprenyl in the management of pituitary-dependent hyperadrenocorticism (cushing's disease) |
| US5169868A (en) | 1991-03-01 | 1992-12-08 | University Of Saskatchewan | Aliphatic propargylamines as specific mao-b inhibitors |
| CA2107552C (en) | 1991-04-04 | 2001-08-28 | William G. Tatton | Use of deprenyl to maintain, prevent loss, or recover nerve cell function |
| WO1992021333A2 (en) | 1991-05-24 | 1992-12-10 | Pharmavene, Inc. | Treatment of drug withdrawal symptoms and drug craving with type b monoamine oxidase inhibitors |
| IL99759A (en) | 1991-10-16 | 1997-06-10 | Teva Pharma | Mono-fluorinated derivatives of n-propargyl-1-aminoindan, their preparation and pharmaceutical compositions containing them |
| US5242950A (en) | 1992-04-23 | 1993-09-07 | Somerset Pharmaceuticals, Inc. | Treatment of macular degeneration |
| JP2916978B2 (ja) * | 1993-08-25 | 1999-07-05 | エスエス製薬株式会社 | 放出開始制御型製剤 |
| IL111240A (en) * | 1993-10-18 | 2001-10-31 | Teva Pharma | Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them |
| US6348208B1 (en) | 1995-01-13 | 2002-02-19 | Somerset Pharmaceuticals, Inc. | Methods and pharmaceutical compositions employing desmethylselegiline |
| PE57198A1 (es) * | 1996-03-25 | 1998-10-10 | American Home Prod | Formula de liberacion prolongada |
| IL118836A (en) | 1996-07-11 | 2001-01-11 | Teva Pharma | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan |
| US6251938B1 (en) | 1996-12-18 | 2001-06-26 | Teva Pharmaceutical Industries, Ltd., | Phenylethylamine derivatives |
| ES2241064T3 (es) | 1996-12-18 | 2005-10-16 | Teva Pharmaceutical Industries, Ltd. | Derivados de aminoindano. |
| US5840979A (en) | 1997-07-14 | 1998-11-24 | University Of Saskatchewan | Aliphatic propargylamines as cellular rescue agents |
| WO2000066110A1 (en) | 1999-04-29 | 2000-11-09 | Merck Patent Gmbh | Glycine cleavage system inhibitors as potential antipsychotics |
| MXPA03012041A (es) * | 2001-07-04 | 2004-03-26 | Sun Pharmaceutical Ind Ltd | Sistema de administracion controlada de farmacos de retencion gastrica. |
| US20040076668A1 (en) | 2002-07-03 | 2004-04-22 | Pfizer Inc. | Controlled-release pharmaceutical formulations |
| ES2432117T3 (es) * | 2002-11-15 | 2013-11-29 | Teva Pharmaceutical Industries Limited | Uso de rasagilina con riluzol para tratar la esclerosis lateral amiotrófica |
| WO2005072705A1 (en) * | 2004-01-29 | 2005-08-11 | Neuromolecular, Inc. | Combination of a nmda receptor antagonist and a mao-inhibitor or a gadpf-inhibitor for the treatment of central nervous system-related conditions |
| WO2006014973A2 (en) * | 2004-07-26 | 2006-02-09 | Teva Pharmaceutical Industries, Ltd. | Pharmaceutical dosage forms including rasagiline |
| WO2007000779A2 (en) * | 2005-06-29 | 2007-01-04 | Panacea Biotec Ltd. | Pharmaceutical sustained release compositions and processes thereof |
| WO2007016350A2 (en) * | 2005-07-28 | 2007-02-08 | Supernus Pharmaceuticals, Inc. | Modified release tablet formulations with enhanced mechanical properties |
| US20070048371A1 (en) * | 2005-07-28 | 2007-03-01 | Shojaei Amir H | Pharmaceutical formulations/composition of guanfacine suitable for single dose form administration daily |
| CN101032474B (zh) * | 2006-03-06 | 2011-02-16 | 重庆医药工业研究院有限责任公司 | 一种治疗或预防神经系统疾病的雷沙吉兰透皮贴片及其制备方法 |
| CN101486655A (zh) * | 2008-01-17 | 2009-07-22 | 美德(江西)生物科技有限公司 | 甲磺酸雷沙吉兰晶形及其制备方法 |
| CN102105169B (zh) | 2008-06-06 | 2014-09-10 | 图必制药公司 | 用于治疗帕金森病的药物组合物 |
| WO2009151594A1 (en) * | 2008-06-10 | 2009-12-17 | Teva Pharmaceutical Industries, Ltd. | Rasagiline soft gelatin capsules |
| US20100041920A1 (en) * | 2008-07-18 | 2010-02-18 | Stephen Benedict David Winter | New salt forms of an aminoindan derivative |
| EP2218444A3 (en) * | 2009-01-23 | 2010-08-25 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline formulation |
| JP6045347B2 (ja) * | 2010-02-03 | 2016-12-14 | ファーマ ツー ビー リミテッド | ラサギリンの持続放出性製剤およびその使用 |
-
2011
- 2011-02-03 JP JP2012551732A patent/JP6045347B2/ja active Active
- 2011-02-03 EP EP11707489.8A patent/EP2531181B1/en active Active
- 2011-02-03 BR BR112012019374-0A patent/BR112012019374B1/pt active IP Right Grant
- 2011-02-03 HU HUE11707489 patent/HUE044221T2/hu unknown
- 2011-02-03 EP EP19159171.8A patent/EP3517103A1/en not_active Withdrawn
- 2011-02-03 PL PL11707489T patent/PL2531181T3/pl unknown
- 2011-02-03 MX MX2012009079A patent/MX354423B/es active IP Right Grant
- 2011-02-03 US US13/577,099 patent/US9943489B2/en active Active
- 2011-02-03 CA CA2789006A patent/CA2789006C/en active Active
- 2011-02-03 KR KR1020127023006A patent/KR101791715B1/ko active Active
- 2011-02-03 RU RU2016141314A patent/RU2734632C2/ru active
- 2011-02-03 ES ES11707489T patent/ES2733133T3/es active Active
- 2011-02-03 DK DK11707489.8T patent/DK2531181T3/da active
- 2011-02-03 CN CN201180012590.4A patent/CN102791258B/zh active Active
- 2011-02-03 AU AU2011212068A patent/AU2011212068B2/en active Active
- 2011-02-03 RU RU2012136723A patent/RU2607595C2/ru active
- 2011-02-03 RS RS20190810A patent/RS58988B1/sr unknown
- 2011-02-03 WO PCT/IL2011/000126 patent/WO2011095973A1/en not_active Ceased
- 2011-02-03 SG SG2012057493A patent/SG183150A1/en unknown
- 2011-02-03 LT LTEP11707489.8T patent/LT2531181T/lt unknown
- 2011-02-03 NZ NZ602111A patent/NZ602111A/en not_active IP Right Cessation
- 2011-02-03 TR TR2019/09277T patent/TR201909277T4/tr unknown
- 2011-02-03 PT PT11707489T patent/PT2531181T/pt unknown
-
2012
- 2012-08-02 IL IL221274A patent/IL221274A/en active IP Right Grant
- 2012-08-03 CL CL2012002175A patent/CL2012002175A1/es unknown
- 2012-08-28 ZA ZA2012/06462A patent/ZA201206462B/en unknown
-
2016
- 2016-09-26 JP JP2016186945A patent/JP6440662B2/ja active Active
-
2018
- 2018-11-20 JP JP2018216973A patent/JP6770564B2/ja active Active
-
2019
- 2019-07-03 CY CY20191100699T patent/CY1121781T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |