JP6041823B2 - トファシチニブの経口持続放出剤形 - Google Patents

トファシチニブの経口持続放出剤形 Download PDF

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JP6041823B2
JP6041823B2 JP2014045951A JP2014045951A JP6041823B2 JP 6041823 B2 JP6041823 B2 JP 6041823B2 JP 2014045951 A JP2014045951 A JP 2014045951A JP 2014045951 A JP2014045951 A JP 2014045951A JP 6041823 B2 JP6041823 B2 JP 6041823B2
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tofacitinib
dosage form
coating
pharmaceutical dosage
acid
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Japanese (ja)
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JP2014181234A (ja
JP2014181234A5 (OSRAM
Inventor
スコット　マックス　ハービッグ
マックス ハービッグ スコット
クリシュナスワミ スリラム
クリシュナスワミ スリラム
クシュナー フォー ジョセフ
クシュナー フォー ジョセフ
ラムバ マニシャ
ラムバ マニシャ
シー． ストック トーマス
シー． ストック トーマス
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ファイザー・インク
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K9/2022—Organic macromolecular compounds
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
JP2014045951A 2013-03-16 2014-03-10 トファシチニブの経口持続放出剤形 Active JP6041823B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361802479P 2013-03-16 2013-03-16
US61/802,479 2013-03-16
US201361864059P 2013-08-09 2013-08-09
US61/864,059 2013-08-09
US201461934428P 2014-01-31 2014-01-31
US61/934,428 2014-01-31

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016174293A Division JP6314188B2 (ja) 2013-03-16 2016-09-07 トファシチニブの経口持続放出剤形

Publications (3)

Publication Number Publication Date
JP2014181234A JP2014181234A (ja) 2014-09-29
JP2014181234A5 JP2014181234A5 (OSRAM) 2015-09-17
JP6041823B2 true JP6041823B2 (ja) 2016-12-14

Family

ID=50819757

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014045951A Active JP6041823B2 (ja) 2013-03-16 2014-03-10 トファシチニブの経口持続放出剤形
JP2016174293A Active JP6314188B2 (ja) 2013-03-16 2016-09-07 トファシチニブの経口持続放出剤形
JP2018058176A Pending JP2018100300A (ja) 2013-03-16 2018-03-26 トファシチニブの経口持続放出剤形

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016174293A Active JP6314188B2 (ja) 2013-03-16 2016-09-07 トファシチニブの経口持続放出剤形
JP2018058176A Pending JP2018100300A (ja) 2013-03-16 2018-03-26 トファシチニブの経口持続放出剤形

Country Status (22)

Country Link
US (4) US9937181B2 (OSRAM)
EP (3) EP3854400A1 (OSRAM)
JP (3) JP6041823B2 (OSRAM)
KR (5) KR20150131238A (OSRAM)
CN (2) CN105101952B (OSRAM)
AU (2) AU2014233850B2 (OSRAM)
BR (1) BR112015020453B1 (OSRAM)
CA (2) CA2905604C (OSRAM)
CY (1) CY1124007T1 (OSRAM)
DK (1) DK2968155T3 (OSRAM)
ES (1) ES2865134T3 (OSRAM)
HU (1) HUE053911T2 (OSRAM)
IL (3) IL241400B (OSRAM)
MX (1) MX2021000550A (OSRAM)
NZ (2) NZ710792A (OSRAM)
PL (1) PL2968155T3 (OSRAM)
PT (1) PT2968155T (OSRAM)
SG (2) SG10201810985XA (OSRAM)
SI (1) SI2968155T1 (OSRAM)
TW (1) TWI619516B (OSRAM)
WO (1) WO2014147526A1 (OSRAM)
ZA (2) ZA201505468B (OSRAM)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2759924B2 (ja) 1995-08-11 1998-05-28 株式会社ゼクセル 燃料噴射装置の噴射時期検出装置
JP6041823B2 (ja) 2013-03-16 2016-12-14 ファイザー・インク トファシチニブの経口持続放出剤形
GB201402070D0 (en) * 2014-02-07 2014-03-26 Galapagos Nv Pharmaceutical compositions for the treatment of inflammatory disorders
US20170151244A1 (en) * 2014-06-23 2017-06-01 Sun Pharmaceutical Industries Limited Oral pharmaceutical composition of tofacitinib
AR101476A1 (es) 2014-08-07 2016-12-21 Acerta Pharma Bv Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk)
CN104622827A (zh) * 2015-03-05 2015-05-20 重庆华邦制药有限公司 托法替布片剂及其制备方法
KR20180014778A (ko) * 2015-06-03 2018-02-09 트리아스텍 인코포레이티드 제형 및 이의 용도
US12133911B2 (en) * 2015-06-09 2024-11-05 Capsugel Belgium Nv Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules
US20180214383A1 (en) * 2015-07-16 2018-08-02 National University Of Singapore Printing drug tablets with fully customizable release profiles for personalized medicine
JP6507272B2 (ja) * 2015-07-27 2019-04-24 ユニケム ラボラトリーズ リミテッド トファシチニブ口腔内崩壊錠
US20170049774A1 (en) * 2015-08-19 2017-02-23 Sun Pharmaceutical Industries Limited Sustained release oral pharmaceutical compositions of tofacitinib
US20180311247A1 (en) * 2015-10-02 2018-11-01 Gilead Sciences, Inc. Combination therapies for treating cancers
US10550126B2 (en) 2015-10-16 2020-02-04 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
US12365689B2 (en) 2015-10-16 2025-07-22 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
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