JP6033767B2 - 核酸を含有する細胞または別の生体材料を分析する方法 - Google Patents

核酸を含有する細胞または別の生体材料を分析する方法 Download PDF

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JP6033767B2
JP6033767B2 JP2013503178A JP2013503178A JP6033767B2 JP 6033767 B2 JP6033767 B2 JP 6033767B2 JP 2013503178 A JP2013503178 A JP 2013503178A JP 2013503178 A JP2013503178 A JP 2013503178A JP 6033767 B2 JP6033767 B2 JP 6033767B2
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cell
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cells
formula
fluorescence
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JP2013528571A (ja
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ポール・ジェームズ・スミス
レイチェル・ジェイ・エリントン
ローレンス・ヒルトン・パターソン
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バイオステータス・リミテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B1/00—Dyes with anthracene nucleus not condensed with any other ring
    • C09B1/16—Amino-anthraquinones
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B1/00—Dyes with anthracene nucleus not condensed with any other ring
    • C09B1/16—Amino-anthraquinones
    • C09B1/20—Preparation from starting materials already containing the anthracene nucleus
    • C09B1/207—Dyes with amino groups and with onium groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1003—Carbocyclic compounds
    • C09K2211/1011—Condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/302—Stain compositions

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2013503178A 2010-04-09 2011-04-08 核酸を含有する細胞または別の生体材料を分析する方法 Active JP6033767B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1005939.2 2010-04-09
GBGB1005939.2A GB201005939D0 (en) 2010-04-09 2010-04-09 Method of analysing a cell or other biological material containing nucleic acid
PCT/GB2011/050702 WO2011124927A1 (en) 2010-04-09 2011-04-08 Method of analysing a cell or other biological material containing a nucleic acid

Related Child Applications (1)

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JP2016209377A Division JP6586070B2 (ja) 2010-04-09 2016-10-26 核酸を含有する細胞または別の生体材料を分析する方法

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JP2013528571A JP2013528571A (ja) 2013-07-11
JP2013528571A5 JP2013528571A5 (enExample) 2014-05-29
JP6033767B2 true JP6033767B2 (ja) 2016-11-30

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JP2016209377A Active JP6586070B2 (ja) 2010-04-09 2016-10-26 核酸を含有する細胞または別の生体材料を分析する方法

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US (2) US9051467B2 (enExample)
EP (2) EP3366667B1 (enExample)
JP (2) JP6033767B2 (enExample)
KR (2) KR101846491B1 (enExample)
CN (1) CN102947266B (enExample)
AU (2) AU2011236610B2 (enExample)
BR (1) BR112012025820B1 (enExample)
CA (1) CA2797440C (enExample)
DK (2) DK2556047T3 (enExample)
ES (1) ES2676351T3 (enExample)
GB (1) GB201005939D0 (enExample)
HU (1) HUE038706T2 (enExample)
NO (1) NO2556047T3 (enExample)
PL (1) PL2556047T3 (enExample)
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Cited By (1)

* Cited by examiner, † Cited by third party
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JP2017112988A (ja) * 2010-04-09 2017-06-29 バイオステータス・リミテッド 核酸を含有する細胞または別の生体材料を分析する方法

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US8790892B2 (en) 2011-04-04 2014-07-29 Biotium, Inc. Substituted anthraquinone dyes for cellular stains and enzyme detection
JP2013094135A (ja) * 2011-11-02 2013-05-20 Waseda Univ 人工ナノ材料の安全性を評価する方法
US9933341B2 (en) 2012-04-05 2018-04-03 Becton, Dickinson And Company Sample preparation for flow cytometry
CN104379760B (zh) * 2012-04-05 2018-03-16 Bd公司 用于流式细胞术的样品制备
US9709500B2 (en) 2012-05-02 2017-07-18 Charles River Laboratories, Inc. Optical method for detecting viable microorganisms in a cell sample
EP2769204B1 (en) 2012-05-02 2016-02-17 Charles River Laboratories, Inc. Cell capture system and use thereof
US8993260B2 (en) 2012-05-02 2015-03-31 Charles River Laboratories, Inc. Fluorescence-based viability staining method using a membrane permeable flourescent dye and membrane impermeable fluorescence quencher
GB201214169D0 (en) 2012-08-08 2012-09-19 Biostatus Ltd New compounds and uses thereof
WO2015095152A1 (en) * 2013-12-17 2015-06-25 The Penn State Research Foundation Manipulation of light spectral quality to reduce parasitism by cuscuta and other plant parasites
GB201610971D0 (en) 2016-06-23 2016-08-10 Biostatus Ltd Compounds
CN113667323B (zh) * 2019-11-21 2023-07-14 苏州优逸兰迪生物科技有限公司 一种染料化合物的制备方法
CN112679543B (zh) * 2020-12-29 2022-07-22 天津全和诚科技有限责任公司 一种亲脂性荧光素探针及其制备方法
CN113072937B (zh) * 2021-04-12 2022-06-07 郑州大学 一种脂滴靶向碳点、制备方法及应用

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FR1379649A (fr) * 1963-06-20 1964-11-27 Oreal Nouveaux colorants anthraquinoniques et leur utilisation pour la teinture des cheveux
GB1053536A (enExample) * 1962-10-29
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US3646072A (en) * 1970-07-27 1972-02-29 Du Pont Turquoise biscationic anthraquinone dyes
JPS503337A (enExample) 1973-05-11 1975-01-14
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FR2431128A1 (fr) * 1978-07-13 1980-02-08 Oreal Procede d'evaluation de l'etat ionique des cheveux
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US5057413A (en) 1988-06-13 1991-10-15 Becton, Dickinson And Company Method for discriminating between intact and damaged cells in a sample
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JPH04136802A (ja) * 1990-09-28 1992-05-11 Nippon Kayaku Co Ltd 着色フィルター
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EP1147147A1 (en) * 1998-12-07 2001-10-24 Eastman Chemical Company A colorant composition, a polymer nanocomposite comprising the colorant composition and articles produced therefrom
US6562785B1 (en) * 1999-03-23 2003-05-13 Howard M. Shapiro Method for overcoming bacterial antibiotic resistance
KR20030010585A (ko) * 2000-02-28 2003-02-05 다이이치 가가쿠 야쿠힝 가부시키가이샤 아연 형광탐침
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JP2017112988A (ja) * 2010-04-09 2017-06-29 バイオステータス・リミテッド 核酸を含有する細胞または別の生体材料を分析する方法

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KR101957288B1 (ko) 2019-03-12
BR112012025820B1 (pt) 2020-05-12
HUE038706T2 (hu) 2018-11-28
CN102947266A (zh) 2013-02-27
DK3366667T3 (da) 2021-05-10
WO2011124927A1 (en) 2011-10-13
US11255761B2 (en) 2022-02-22
EP3366667A1 (en) 2018-08-29
US20130101994A1 (en) 2013-04-25
CA2797440A1 (en) 2011-10-13
GB201005939D0 (en) 2010-05-26
KR20130083836A (ko) 2013-07-23
JP2013528571A (ja) 2013-07-11
ES2676351T3 (es) 2018-07-18
PL2556047T3 (pl) 2018-10-31
BR112012025820A2 (pt) 2016-06-28
CA2797440C (en) 2020-01-28
EP2556047B1 (en) 2018-06-06
DK2556047T3 (en) 2018-07-16
AU2016250384B2 (en) 2018-05-10
US20150268142A1 (en) 2015-09-24
AU2011236610B2 (en) 2016-07-28
AU2016250384A1 (en) 2016-11-17
PT2556047T (pt) 2018-07-11
EP3366667B1 (en) 2021-02-17
JP6586070B2 (ja) 2019-10-02
EP2556047A1 (en) 2013-02-13
KR20180037318A (ko) 2018-04-11
JP2017112988A (ja) 2017-06-29
CN102947266B (zh) 2016-02-03
US9051467B2 (en) 2015-06-09
NO2556047T3 (enExample) 2018-11-03
KR101846491B1 (ko) 2018-04-06

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