JP6012473B2 - 抗ｃｄ２００抗体を用いたヒトの処置における免疫調節効果のバイオマーカー - Google Patents

抗ｃｄ２００抗体を用いたヒトの処置における免疫調節効果のバイオマーカー Download PDF

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JP6012473B2
JP6012473B2 JP2012548220A JP2012548220A JP6012473B2 JP 6012473 B2 JP6012473 B2 JP 6012473B2 JP 2012548220 A JP2012548220 A JP 2012548220A JP 2012548220 A JP2012548220 A JP 2012548220A JP 6012473 B2 JP6012473 B2 JP 6012473B2
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antibody
cells
human
concentration
patient
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JP2013516494A (ja
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マクナイト， スーザン ファーズ
マクナイト， スーザン ファーズ
ロクザーン コフィール，
ロクザーン コフィール，
ヤン ヤン，
ヤン ヤン，
アンジリー クックレジャ，
アンジリー クックレジャ，
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アレクシオン ファーマシューティカルズ， インコーポレイテッド
アレクシオン ファーマシューティカルズ， インコーポレイテッド
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JP2012548220A 2010-01-11 2011-01-11 抗ｃｄ２００抗体を用いたヒトの処置における免疫調節効果のバイオマーカー Expired - Fee Related JP6012473B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US29406610P 2010-01-11 2010-01-11
US61/294,066 2010-01-11
US33799710P 2010-02-11 2010-02-11
US61/337,997 2010-02-11
US40144210P 2010-08-12 2010-08-12
US61/401,442 2010-08-12
US41697410P 2010-11-24 2010-11-24
US61/416,974 2010-11-24
PCT/US2011/020750 WO2011085343A1 (en) 2010-01-11 2011-01-11 Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies

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JP2015106061A Division JP2015155465A (ja) 2010-01-11 2015-05-26 抗ｃｄ２００抗体を用いたヒトの処置における免疫調節効果のバイオマーカー

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JP2013516494A JP2013516494A (ja) 2013-05-13
JP6012473B2 true JP6012473B2 (ja) 2016-10-25

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JP2015106061A Withdrawn JP2015155465A (ja) 2010-01-11 2015-05-26 抗ｃｄ２００抗体を用いたヒトの処置における免疫調節効果のバイオマーカー

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US (2) US9180186B2 (enExample)
EP (1) EP2523976B1 (enExample)
JP (2) JP6012473B2 (enExample)
KR (1) KR20130005264A (enExample)
CN (1) CN102906115A (enExample)
AU (1) AU2011203879A1 (enExample)
CA (1) CA2786692A1 (enExample)
IN (1) IN2012DN06309A (enExample)
MX (1) MX2012008108A (enExample)
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RU (1) RU2012134369A (enExample)
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JP6150734B2 (ja) 2011-02-03 2017-06-21 アレクシオン ファーマシューティカルズ， インコーポレイテッド 同種移植片の生存を長期化するための抗ｃｄ２００抗体の使用
CN102698266A (zh) * 2012-05-15 2012-10-03 中国医学科学院北京协和医院 Cd200在制备系统性红斑狼疮治疗药物中的应用
AU2013285355A1 (en) 2012-07-06 2015-01-29 Genmab B.V. Dimeric protein with triple mutations
EP2956772B1 (en) * 2013-02-14 2018-05-30 Faron Pharmaceuticals OY A method for determining acute respiratory distress syndrome (ards) related biomarkers, a method to monitor the development and treatment of ards in a patient
JP7022067B2 (ja) * 2016-01-14 2022-02-17 メモリアル スローン ケタリング キャンサー センター Ｆｏｘｐ３由来のペプチドに特異的なｔ細胞受容体様抗体
GB201608197D0 (en) * 2016-05-10 2016-06-22 Ducentis Biotherapeutics Ltd Novel proteins
WO2018075408A1 (en) 2016-10-17 2018-04-26 Alexion Pharmaceuticals, Inc. Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin
WO2018102594A1 (en) 2016-12-01 2018-06-07 Alexion Pharmaceuticals, Inc. Methods of treating solid tumors with anti-cd200 antibodies
CN118184781A (zh) * 2017-05-08 2024-06-14 阿迪马布有限责任公司 抗cd3结合结构域和包含它们的抗体以及它们的产生及使用方法
WO2019067499A1 (en) 2017-09-27 2019-04-04 Alexion Pharmaceuticals, Inc. BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY
US11802154B2 (en) 2017-12-20 2023-10-31 Alexion Pharmaceuticals, Inc. Humanized anti-CD200 antibodies and uses thereof
US12139533B2 (en) 2017-12-20 2024-11-12 Alexion Pharmaceuticals, Inc. Liquid formulations of anti-CD200 antibodies
TWI749367B (zh) * 2018-09-14 2021-12-11 美商美國禮來大藥廠 Cd200r促效劑抗體及其用途
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EP2523976A1 (en) 2012-11-21
US20130202602A1 (en) 2013-08-08
US9180186B2 (en) 2015-11-10
MX2012008108A (es) 2012-10-03
WO2011085343A1 (en) 2011-07-14
SG182408A1 (en) 2012-08-30
EP2523976A4 (en) 2013-10-30
US20160033514A1 (en) 2016-02-04
KR20130005264A (ko) 2013-01-15
RU2012134369A (ru) 2014-02-20
JP2015155465A (ja) 2015-08-27
JP2013516494A (ja) 2013-05-13
NZ601111A (en) 2014-07-25
AU2011203879A1 (en) 2012-08-02
CA2786692A1 (en) 2011-07-14
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CN102906115A (zh) 2013-01-30

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